University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Kord Kober, PhD

Kord Kober, PhD

Assistant Professor, Physiological Nursing, UCSF

Cancer Center Program Memberships

Breast Oncology

Research Summary

Dr. Kober is highly qualified to serve as a co-investigator, geneticist and bioinformatician for the proposed project. Dr. Kober has worked in this capacity both in the Academic (e.g., UC Santa Cruz Genome Browser) and non-Academic (e.g., Navigenics, Inc) environments. He has in-depth experience in computer science, biochemistry, and molecular evolution, the later which requires considered expertise in bioinformatics (i.e., scripting languages, data management and visualization, interrogation and deposition of data into public databases with strict formatting requirements). He has experience in molecular analysis of cancer related symptoms. He has worked both at the wet bench (i.e., molecular biologist) and in the dry laboratory (i.e., Bioinformatician) for over 10 years. He is experienced with the molecular and data analytic procedures described in the current application. Of note, Dr. Kober plays a key role in an NIH-funded Biostatistics and Bioinformatics Group as part of the NIH NIAID-funded Women’s Interagency HIV Study (WIHS), which currently focused primarily on genome wide association studies and large-scale molecular data analyses. He will bring these experiences to the proposed project.

Education

University of California, Los Angeles, BS, 06/96, Biochemistry
University of California, Santa Cruz, MA, 06/09, Molecular Evolutionary Biology
University of California, Santa Cruz, PhD, 06/12, Molecular Evolutionary Biology


Professional Experience

  • 1997-2000
    Programmer Analyst, Information Services & Technology, UC Berkeley
  • 2000-2004
    Unix Systems Architect, eCommerce, Moët Hennessy Louis Vuitton S.A. & Prosodie Interactive
  • 2000-present
    Founder, Board member, Secretary, Treasurer, Benjamin Links. A 501(c)3 public benefit charity for families of children with Autism.
  • 2004-2005
    Director, eCommerce, Moët Hennessy Louis Vuitton S.A. & Prosodie Interactive
  • 2006-2008
    Research Associate (Molecular Genetics), Physiological Nursing, UCSF School of Nursing
  • 2008-2009
    Bioinformatics Consultant (Personal Genomics), Research and Development, Navigenics, Inc.
  • 2010-2011
    Biological Data Engineer (Cancer Genomics), Cancer Genome Browser, UC Santa Cruz
  • 2011-2011
    Bioinformatics Consultant (Personal Genomics), Research and Development, Navigenics, Inc.
  • 2011-2013
    Bioinformaticist (Genomics of Human Disease), Physiological Nursing/ WIHS Genomics Unit, UCSF School of Nursing
  • 2013-present
    Assistant Professor, Physiological Nursing, UCSF School of Nursing
  • 2013-present
    Vice-Chair, UCSF Genomics Working Group, Women's Interagency HIV Study

Honors & Awards

  • 2006
    Regents' Fellowship, University of California, Santa Cruz, CA
  • 2007
    STEPS Institute Graduate Research Grant Award, University of California, Santa Cruz, CA
  • 2007
    Summer Research Fellowship, Dept. of EE Biology, University Of California, Santa Cruz, CA
  • 2007
    Student Research and Education Award, Friends of Long Marine Lab, Santa Cruz, CA
  • 2008
    Summer Research Fellowship, Dept. of EE Biology, University Of California, Santa Cruz, CA
  • 2011
    Graduate Student Support Award, CSHL Meeting on The Biology of Genomes
  • 2011
    Research Award, Dr. Earl H. Myers and Ethel M. Myers Oceonographic and Marine Biology Trust
  • 2013
    Annual Meeting Best Poster Nominee, American Pain Society
  • 2014
    New Investigator Abstract Award (Fatigue Study Group), MASCC
  • 2015
    Faculty Learning and Development, UCSF Chancellor’s Fund

Selected Publications

  1. Tejada M, Viele C, Kober KM, Cooper BA, Paul SM, Dunn LB, Hammer MJ, Wright F, Conley YP, Levine JD, Miaskowski C. Identification of subgroups of chemotherapy patients with distinct sleep disturbance profiles and associated co-occurring symptoms. Sleep. 2019 Oct 09; 42(10).
    View on PubMed
  2. Kober K, Schumacher MA, Conley YP, Topp K, Mazor M, Hammer M, Paul S, Levine J, Miaskowski C. [EXPRESS] Signaling Pathways and Gene Co-Expression Modules Associated with Cytoskeleton and Axon Morphology in Breast Cancer Survivors with Chronic Paclitaxel-Induced Peripheral Neuropathy. Mol Pain. 2019 Sep 05; 1744806919878088.
    View on PubMed
  3. Wright F, Dunn LB, Paul SM, Conley YP, Levine JD, Hammer MJ, Cooper BA, Miaskowski C, Kober KM. Morning Fatigue Severity Profiles in Oncology Outpatients Receiving Chemotherapy. Cancer Nurs. 2019 Sep/Oct; 42(5):355-364.
    View on PubMed
  4. Singh K, Kober KM, Paul SM, Hammer M, Wright F, Conley YP, Levine JD, Miaskowski C. Gastrointestinal symptoms are associated with trajectories of chemotherapy-induced nausea. Support Care Cancer. 2019 Aug 19.
    View on PubMed
  5. Greenblatt R, Bacchetti P, Boylan R, Kober K, Springer G, Anastos K, Busch M, Cohen M, Kassaye S, Gustafson D, Aouizerat B. Genetic and clinical predictors of CD4 lymphocyte recovery during suppressive antiretroviral therapy: Whole exome sequencing and antiretroviral therapy response phenotypes. PLoS One. 2019; 14(8):e0219201.
    View on PubMed
  6. Han CJ, Reding K, Cooper BA, Paul SM, Conley YP, Hammer M, Kober KM, Levine JD, Miaskowski C. Stability of Symptom Clusters in Patients With Gastrointestinal Cancers Receiving Chemotherapy. J Pain Symptom Manage. 2019 Aug 09.
    View on PubMed
  7. Miaskowski C, Topp K, Conley YP, Paul SM, Melisko M, Schumacher M, Chesney M, Abrams G, Levine JD, Kober KM. Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. J Neuroimmunol. 2019 Oct 15; 335:577019.
    View on PubMed
  8. Chan A, Hertz DL, Morales M, Adams EJ, Gordon S, Tan CJ, Staff NP, Kamath J, Oh J, Shinde S, Pon D, Dixit N, D'Olimpio J, Dumitrescu C, Gobbo M, Kober K, Mayo S, Pang L, Subbiah I, Beutler AS, Peters KB, Loprinzi C, Lustberg MB. Biological predictors of chemotherapy-induced peripheral neuropathy (CIPN): MASCC neurological complications working group overview. Support Care Cancer. 2019 Oct; 27(10):3729-3737.
    View on PubMed
  9. Nolden A, Joseph PV, Kober KM, Cooper BA, Paul SM, Hammer MJ, Dunn LB, Conley YP, Levine JD, Miaskowski C. Co-occurring Gastrointestinal Symptoms Are Associated With Taste Changes in Oncology Patients Receiving Chemotherapy. J Pain Symptom Manage. 2019 Jul 23.
    View on PubMed
  10. Petrovchich I, Kober KM, Wagner L, Paul SM, Abrams G, Chesney MA, Topp K, Smoot B, Schumacher M, Conley YP, Hammer M, Levine JD, Miaskowski C. Deleterious Effects of Higher Body Mass Index on Subjective and Objective Measures of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors. J Pain Symptom Manage. 2019 Aug; 58(2):252-263.
    View on PubMed
  11. Papachristou N, Barnaghi P, Cooper B, Kober KM, Maguire R, Paul SM, Hammer M, Wright F, Armes J, Furlong EP, McCann L, Conley YP, Patiraki E, Katsaragakis S, Levine JD, Miaskowski C. Network Analysis of the Multidimensional Symptom Experience of Oncology. Sci Rep. 2019 Feb 19; 9(1):2258.
    View on PubMed
  12. Wong ML, Cooper BA, Paul SM, Abrams G, Topp K, Kober KM, Chesney MA, Mazor M, Schumacher MA, Conley YP, Levine JD, Miaskowski C. Age-related differences in patient-reported and objective measures of chemotherapy-induced peripheral neuropathy among cancer survivors. Support Care Cancer. 2019 Oct; 27(10):3905-3912.
    View on PubMed
  13. Flowers E, Flentje A, Levine J, Olshen A, Hammer M, Paul S, Conley Y, Miaskowski C, Kober KM. A Pilot Study Using a Multistaged Integrated Analysis of Gene Expression and Methylation to Evaluate Mechanisms for Evening Fatigue in Women Who Received Chemotherapy for Breast Cancer. Biol Res Nurs. 2019 03; 21(2):142-156.
    View on PubMed
  14. Miaskowski C, Paul SM, Mastick J, Abrams G, Topp K, Smoot B, Kober KM, Chesney M, Schumacher M, Conley YP, Hammer M, Cheung S, Borsook D, Levine JD. Contribution of Loss of Large Fiber Function to Pain in 2 Samples of Oncology Patients. Clin J Pain. 2019 01; 35(1):37-42.
    View on PubMed
  15. Papachristou N, Puschmann D, Barnaghi P, Cooper B, Hu X, Maguire R, Apostolidis K, Conley YP, Hammer M, Katsaragakis S, Kober KM, Levine JD, McCann L, Patiraki E, Furlong EP, Fox PA, Paul SM, Ream E, Wright F, Miaskowski C. Learning from data to predict future symptoms of oncology patients. PLoS One. 2018; 13(12):e0208808.
    View on PubMed
  16. Kober KM, Olshen A, Conley YP, Schumacher M, Topp K, Smoot B, Mazor M, Chesney M, Hammer M, Paul SM, Levine JD, Miaskowski C. Expression of mitochondrial dysfunction-related genes and pathways in paclitaxel-induced peripheral neuropathy in breast cancer survivors. Mol Pain. 2018 Jan-Dec; 14:1744806918816462.
    View on PubMed
  17. Mazor M, Smoot BJ, Mastick J, Mausisa G, Paul SM, Kober KM, Elboim C, Singh K, Conley YP, Mickevicius G, Field J, Hutchison H, Miaskowski C. Assessment of local tissue water in the arms and trunk of breast cancer survivors with and without upper extremity lymphoedema. Clin Physiol Funct Imaging. 2019 Jan; 39(1):57-64.
    View on PubMed
  18. Kober KM, Mazor M, Abrams G, Olshen A, Conley YP, Hammer M, Schumacher M, Chesney M, Smoot B, Mastick J, Paul SM, Levine JD, Miaskowski C. Phenotypic Characterization of Paclitaxel-Induced Peripheral Neuropathy in Cancer Survivors. J Pain Symptom Manage. 2018 12; 56(6):908-919.e3.
    View on PubMed
  19. Singh KP, Kober KM, Dhruva AA, Flowers E, Paul SM, Hammer MJ, Cartwright F, Wright F, Conley YP, Levine JD, Miaskowski C. Risk Factors Associated With Chemotherapy-Induced Nausea in the Week Before the Next Cycle and Impact of Nausea on Quality of Life Outcomes. J Pain Symptom Manage. 2018 09; 56(3):352-362.
    View on PubMed
  20. Knisely MR, Conley YP, Kober KM, Smoot B, Paul SM, Levine JD, Miaskowski C. Associations Between Catecholaminergic and Serotonergic Genes and Persistent Breast Pain Phenotypes After Breast Cancer Surgery. J Pain. 2018 10; 19(10):1130-1146.
    View on PubMed

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