University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Bin Liu, PhD

Bin Liu, PhD

Professor, Department of Anesthesia, UCSF

Cancer Center Program Memberships

Prostate Cancer

Education

Princeton University, B.A., June 1990, Molecular Biology and Biochemical Sciences
University of California, San Francisco, Ph.D., Dec. 1994, Biochemistry and Biophysics


Professional Experience

  • 1995-1997
    Visiting fellow, Department of Dermatology, University of California school of medicine, San Francisco, California
  • 1998-2001
    Visiting fellow, Department of Anesthesia and Pharmaceutical chemistry, San Francisco General Hospital, San Francisco, California.
  • 2002-2006
    Assistant Professor, Department of Anesthesia, University of California, San Francisco.
  • 2006-2011
    Associate Professor, Department of Anesthesia, University of California, San Francisco.
  • 2011-present
    Professor, Department of Anesthesia, University of California, San Francisco.
  • 2003-present
    Program member, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco.

Honors & Awards

  • 1990
    Summa Cum Laude (Princeton University)
  • 1990
    Phi Beta Kappa (Princeton University)
  • 1990
    Sigma Xi (Princeton University)
  • 1990
    Sigma Xi Book Award (Princeton University)
  • 1990
    E.R. Squibb and Sons Thesis Prize (Princeton University)
  • 1990
    George Khoury’65 Prize For Academic Excellence (Princeton University)
  • 1990,1991
    Regents’ Fellow (University of California at San Francisco)
  • 1994
    Chancellor's Fellow (University of California at San Francisco)
  • 1996-1999
    SmithKline Beecham Fellow of the Life Sciences Research Foundation
  • 1998
    Scleroderma Research Foundation investigator award
  • 2002
    American Cancer Society intramural research award
  • 2002
    BioSTAR/UC Discovery award
  • 2002
    CaPCure research award
  • 2002
    DOD New Investigator award
  • 2004
    MARF Investigator award
  • 2006
    MARF Investigator award
  • 2008
    AACR PanCan Pilot award
  • 2009
    UC Discovery SEED award
  • 2011
    MARF Investigator award

Selected Publications

  1. Behrens CR, Liu B. Methods for site-specific drug conjugation to antibodies. MAbs. 2014 Jan-Feb; 6(1):46-53.
    View on PubMed
  2. Federman N, Chan J, Nagy JO, Landaw EM, McCabe K, Wu AM, Triche T, Kang H, Liu B, Marks JD, Denny CT. Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor. Sarcoma. 2012; 2012:126906.
    View on PubMed
  3. McCabe KE, Liu B, Marks JD, Tomlinson JS, Wu H, Wu AM. An engineered cysteine-modified diabody for imaging activated leukocyte cell adhesion molecule (ALCAM)-positive tumors. Mol Imaging Biol. 2012 Jun; 14(3):336-47.
    View on PubMed
  4. Iyer AK, Lan X, Zhu X, Su Y, Feng J, Zhang X, Gao D, Seo Y, Vanbrocklin HF, Broaddus VC, Liu B, He J. Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas. Cancer Res. 2011 Apr 01; 71(7):2428-32.
    View on PubMed
  5. Iyer AK, Su Y, Feng J, Lan X, Zhu X, Liu Y, Gao D, Seo Y, Vanbrocklin HF, Courtney Broaddus V, Liu B, He J. The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma. Biomaterials. 2011 Apr; 32(10):2605-13.
    View on PubMed
  6. Bidlingmaier S, Liu B. Construction of yeast surface-displayed cDNA libraries. Methods Mol Biol. 2011; 729:199-210.
    View on PubMed
  7. Bidlingmaier S, Liu B. Identification of protein/target molecule interactions using yeast surface-displayed cDNA libraries. Methods Mol Biol. 2011; 729:211-23.
    View on PubMed
  8. Bidlingmaier S, Wang Y, Liu Y, Zhang N, Liu B. Comprehensive analysis of yeast surface displayed cDNA library selection outputs by exon microarray to identify novel protein-ligand interactions. Mol Cell Proteomics. 2011 Mar; 10(3):M110.005116.
    View on PubMed
  9. Chen Y, Zhu X, Zhang X, Liu B, Huang L. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol Ther. 2010 Sep; 18(9):1650-6.
    View on PubMed
  10. Drummond DC, Noble CO, Guo Z, Hayes ME, Connolly-Ingram C, Gabriel BS, Hann B, Liu B, Park JW, Hong K, Benz CC, Marks JD, Kirpotin DB. Development of a highly stable and targetable nanoliposomal formulation of topotecan. J Control Release. 2010 Jan 04; 141(1):13-21.
    View on PubMed
  11. Bidlingmaier S, He J, Wang Y, An F, Feng J, Barbone D, Gao D, Franc B, Broaddus VC, Liu B. Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma. Cancer Res. 2009 Feb 15; 69(4):1570-7.
    View on PubMed
  12. Goenaga AL, Zhou Y, Legay C, Bougherara H, Huang L, Liu B, Drummond DC, Kirpotin DB, Auclair C, Marks JD, Poul MA. Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol. 2007 Jul; 44(15):3777-88.
    View on PubMed
  13. Liu B, Marks JD. Applying phage antibodies to proteomics: selecting single chain Fv antibodies to antigens blotted on nitrocellulose. Anal Biochem. 2000 Nov 01; 286(1):119-28.
    View on PubMed
  14. Liu B, Alberts BM. Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex. Science. 1995 Feb 24; 267(5201):1131-7.
    View on PubMed
  15. Liu B, Wong ML, Alberts B. A transcribing RNA polymerase molecule survives DNA replication without aborting its growing RNA chain. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10660-4.
    View on PubMed
  16. Liu B, Wong ML, Tinker RL, Geiduschek EP, Alberts BM. The DNA replication fork can pass RNA polymerase without displacing the nascent transcript. Nature. 1993 Nov 04; 366(6450):33-9.
    View on PubMed

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