University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Sharmila Majumdar, PhD

Sharmila Majumdar, PhD

Professor and Vice Chair of Research, Department of Radiology and Biomedical Imaging, UCSF

Cancer Center Program Memberships

Non-aligned

Research Summary

Sharmila Majumdar, PhD, is a UCSF Professor and the Vice Chair of Research in the Department of Radiology and Biomedical Imaging and Professor in the Departments of Bioengineering and Therapeutic Sciences, Orthopedic Surgery at UCSF and Bioengineering at UC Berkeley. She is Director of the Musculoskeletal Research Interest Group at UCSF, an interdisciplinary group consisting of faculty, post-doctoral scholars and students. She obtained her PhD degree in Engineering and Applied Science from Yale University in 1987, where she stayed as a post-doctoral researcher and Assistant Professor until 1989, when she joined UCSF.

Her research work on imaging, particularly magnetic resonance and micro computed tomography, and development of image processing and analysis tools, has been focused in the areas of osteoporosis, osteo-arthritis and lower back pain. Her research, which is supported by grants from the NIH and corporate entities, and is diverse ranging from technical development to clinical trials. She currently heads an NIH Center of Research Translation focused on Osteoarthritis and Imaging, a joint effort between UCSF and UC Davis.

Dr. Majumdar was selected as a fellow of the American Institute of Medical and Biological Engineers in 2004 and a fellow of the International Society of Magnetic Resonance in Medicine in 2008. In 2007 she was awarded the “Excellence in Direct Teaching and/or Excellence in Mentoring and Advising Award” by the UCSF Haile T. Debas Academy of Medical Educators.

She has published extensively in the Journal of Bone Mineral Research, Magnetic Resonance in Medicine, and other highly regarded journals. She also serves as a reviewer and is on the editorial board of scientific journals, and is a recognized expert in the area of imaging.

Education

  • St. Stephens College, University of Delhi, India, B.S., 1983, Physics
  • Yale University, Connecticut, USA, M.S., 1984, Eng. & Applied Physics
  • Yale University, Connecticut, USA, Ph.D., 1987, Eng. & Applied Physics
  • Yale University, Connecticut, USA, Postdoctoral, 1988, Radiology

Professional Experience

  • 2001–present
    Professor, Dept. of Radiology, UCSF
  • 2002–2009
    Member, Division of Bioengineering, UCSF
  • 2002–present
    Professor, Dept. of Bioengineering, UC Berkeley
  • 2003–present
    Director, Musculo-skeletal and Quantitative Imaging Research Group, Dept. of Radiology, UCSF
  • 2003–present
    Member, California Institute for Quantitative Biomedical Research (QB3)
  • 2008–present
    Vice Chair, Dept. of Radiology, UCSF
  • 2009–present
    Joint Faculty Member, Dept. of Bioengineering and Therapeutic Sciences, UCSF

Honors & Awards

  • 2002
    Celebrating Woman Faculty, Award and Recognition, Chancellor and Deans of UCSF
  • 2004
    Fellow of the American Institute of Medical and Biological Engineers (AIMBE)
  • 2008
    Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM)
  • 2016
    Gold Medal of International Society of Magnetic Resonance in Medicine (ISMRM)

Selected Publications

  1. Shaw C, Warwick H, Nguyen KH, Link TM, Majumdar S, Souza RB, Vail TP, Zhang AL. Correlation of Hip Capsule Morphology with Patient Symptoms from Femoroacetabular Impingement. J Orthop Res. 2020 Jun 27.
    View on PubMed
  2. Popovic T, Samaan MA, Link TM, Majumdar S, Souza RB. Patients with Symptomatic Hip Osteoarthritis Have Altered Kinematics during Stair Ambulation. PM R. 2020 May 07.
    View on PubMed
  3. Kumar D, Link TM, Jafarzadeh SR, LaValley MP, Majumdar S, Souza RB. Quadriceps adiposity is associated with increase in lesions of the knee cartilage, meniscus, or bone marrow over 3-years. Arthritis Care Res (Hoboken). 2020 Apr 27.
    View on PubMed
  4. Tibrewala R, Ozhinsky E, Shah R, Flament I, Crossley K, Srinivasan R, Souza R, Link TM, Pedoia V, Majumdar S. Computer-Aided Detection AI Reduces Interreader Variability in Grading Hip Abnormalities With MRI. J Magn Reson Imaging. 2020 Apr 15.
    View on PubMed
  5. Tolpadi AA, Lee JJ, Pedoia V, Majumdar S. Deep Learning Predicts Total Knee Replacement from Magnetic Resonance Images. Sci Rep. 2020 Apr 14; 10(1):6371.
    View on PubMed
  6. Morales Martinez A, Caliva F, Flament I, Liu F, Lee J, Cao P, Shah R, Majumdar S, Pedoia V. Learning osteoarthritis imaging biomarkers from bone surface spherical encoding. Magn Reson Med. 2020 Apr 03.
    View on PubMed
  7. Tibrewala R, Pedoia V, Bucknor M, Majumdar S. Principal Component Analysis of Simultaneous PET-MRI Reveals Patterns of Bone-Cartilage Interactions in Osteoarthritis. J Magn Reson Imaging. 2020 Mar 24.
    View on PubMed
  8. Iriondo C, Pedoia V, Majumdar S. Lumbar intervertebral disc characterization through quantitative MRI analysis: An automatic voxel-based relaxometry approach. Magn Reson Med. 2020 Sep; 84(3):1376-1390.
    View on PubMed
  9. Lansdown DA, Xiao W, Zhang AL, Allen CR, Feeley BT, Li X, Majumdar S, Ma CB. Quantitative imaging of anterior cruciate ligament (ACL) graft demonstrates longitudinal compositional changes and relationships with clinical outcomes at 2 years after ACL reconstruction. J Orthop Res. 2019 Dec 23.
    View on PubMed
  10. Samaan MA, Grace T, Zhang AL, Majumdar S, Souza RB. Short term outcomes of hip arthroscopy on hip joint mechanics and cartilage health in patients with femoroacetabular impingement syndrome. Clin Biomech (Bristol, Avon). 2020 01; 71:214-220.
    View on PubMed
  11. Chaudhari AS, Kogan F, Pedoia V, Majumdar S, Gold GE, Hargreaves BA. Rapid Knee MRI Acquisition and Analysis Techniques for Imaging Osteoarthritis. J Magn Reson Imaging. 2019 Nov 21.
    View on PubMed
  12. Foreman SC, Zhang AL, Neumann J, von Schacky CE, Souza RB, Majumdar S, Link TM. Postoperative MRI Findings and Associated Pain Changes After Arthroscopic Surgery for Femoroacetabular Impingement. AJR Am J Roentgenol. 2020 01; 214(1):177-184.
    View on PubMed
  13. Liao TC, Pedoia V, Neumann J, Link TM, Souza RB, Majumdar S. Extracting Voxel-Based Cartilage Relaxometry Features in Hip Osteoarthritis Subjects Using Principal Component Analysis. J Magn Reson Imaging. 2020 Jun; 51(6):1708-1719.
    View on PubMed
  14. Liao TC, Samaan MA, Popovic T, Neumann J, Zhang AL, Link TM, Majumdar S, Souza RB. Abnormal Joint Loading During Gait in Persons With Hip Osteoarthritis Is Associated With Symptoms and Cartilage Lesions. J Orthop Sports Phys Ther. 2019 12; 49(12):917-924.
    View on PubMed
  15. Tibrewala R, Bahroos E, Mehrabian H, Foreman SC, Link TM, Pedoia V, Majumdar S. [18 F]-Sodium Fluoride PET/MR Imaging for Bone-Cartilage Interactions in Hip Osteoarthritis: A Feasibility Study. J Orthop Res. 2019 12; 37(12):2671-2680.
    View on PubMed
  16. Liao TC, Teng HL, Link TM, Majumdar S, Souza RB. Association Between Gait Kinetics and Symptomatic Progression in Persons With Patellofemoral With/Without Concurrent Tibiofemoral Osteoarthritis. J Orthop Res. 2019 12; 37(12):2593-2600.
    View on PubMed
  17. Jenkins NW, Iriondo C, Shah V, Bahroos E, Ravanfar V, Regan M, Seo Y, Dillon WP, Majumdar S, Talbott JF. Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain. J Vis Exp. 2019 Aug 08; (150).
    View on PubMed
  18. Shah RF, Martinez AM, Pedoia V, Majumdar S, Vail TP, Bini SA. Variation in the Thickness of Knee Cartilage. The Use of a Novel Machine Learning Algorithm for Cartilage Segmentation of Magnetic Resonance Images. J Arthroplasty. 2019 Oct; 34(10):2210-2215.
    View on PubMed
  19. Norman B, Pedoia V, Noworolski A, Link TM, Majumdar S. Applying Densely Connected Convolutional Neural Networks for Staging Osteoarthritis Severity from Plain Radiographs. J Digit Imaging. 2019 06; 32(3):471-477.
    View on PubMed
  20. Pedoia V, Lee J, Norman B, Link TM, Majumdar S. Diagnosing osteoarthritis from T2 maps using deep learning: an analysis of the entire Osteoarthritis Initiative baseline cohort. Osteoarthritis Cartilage. 2019 07; 27(7):1002-1010.
    View on PubMed

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