University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Sharmila Majumdar, PhD

Sharmila Majumdar, PhD

Professor and Vice Chair of Research, Department of Radiology and Biomedical Imaging, UCSF

Cancer Center Program Memberships

Non-aligned

Research Summary

Sharmila Majumdar, PhD, is a UCSF Professor and the Vice Chair of Research in the Department of Radiology and Biomedical Imaging and Professor in the Departments of Bioengineering and Therapeutic Sciences, Orthopedic Surgery at UCSF and Bioengineering at UC Berkeley. She is Director of the Musculoskeletal Research Interest Group at UCSF, an interdisciplinary group consisting of faculty, post-doctoral scholars and students. She obtained her PhD degree in Engineering and Applied Science from Yale University in 1987, where she stayed as a post-doctoral researcher and Assistant Professor until 1989, when she joined UCSF.

Her research work on imaging, particularly magnetic resonance and micro computed tomography, and development of image processing and analysis tools, has been focused in the areas of osteoporosis, osteo-arthritis and lower back pain. Her research, which is supported by grants from the NIH and corporate entities, and is diverse ranging from technical development to clinical trials. She currently heads an NIH Center of Research Translation focused on Osteoarthritis and Imaging, a joint effort between UCSF and UC Davis.

Dr. Majumdar was selected as a fellow of the American Institute of Medical and Biological Engineers in 2004 and a fellow of the International Society of Magnetic Resonance in Medicine in 2008. In 2007 she was awarded the “Excellence in Direct Teaching and/or Excellence in Mentoring and Advising Award” by the UCSF Haile T. Debas Academy of Medical Educators.

She has published extensively in the Journal of Bone Mineral Research, Magnetic Resonance in Medicine, and other highly regarded journals. She also serves as a reviewer and is on the editorial board of scientific journals, and is a recognized expert in the area of imaging.

Education

  • St. Stephens College, University of Delhi, India, B.S., 1983, Physics
  • Yale University, Connecticut, USA, M.S., 1984, Eng. & Applied Physics
  • Yale University, Connecticut, USA, Ph.D., 1987, Eng. & Applied Physics
  • Yale University, Connecticut, USA, Postdoctoral, 1988, Radiology

Professional Experience

  • 2001–present
    Professor, Dept. of Radiology, UCSF
  • 2002–2009
    Member, Division of Bioengineering, UCSF
  • 2002–present
    Professor, Dept. of Bioengineering, UC Berkeley
  • 2003–present
    Director, Musculo-skeletal and Quantitative Imaging Research Group, Dept. of Radiology, UCSF
  • 2003–present
    Member, California Institute for Quantitative Biomedical Research (QB3)
  • 2008–present
    Vice Chair, Dept. of Radiology, UCSF
  • 2009–present
    Joint Faculty Member, Dept. of Bioengineering and Therapeutic Sciences, UCSF

Honors & Awards

  • 2002
    Celebrating Woman Faculty, Award and Recognition, Chancellor and Deans of UCSF
  • 2004
    Fellow of the American Institute of Medical and Biological Engineers (AIMBE)
  • 2008
    Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM)
  • 2016
    Gold Medal of International Society of Magnetic Resonance in Medicine (ISMRM)

Selected Publications

  1. Chaudhari AS, Kogan F, Pedoia V, Majumdar S, Gold GE, Hargreaves BA. Rapid Knee MRI Acquisition and Analysis Techniques for Imaging Osteoarthritis. J Magn Reson Imaging. 2019 Nov 21.
    View on PubMed
  2. Foreman SC, Zhang AL, Neumann J, von Schacky CE, Souza RB, Majumdar S, Link TM. Postoperative MRI Findings and Associated Pain Changes After Arthroscopic Surgery for Femoroacetabular Impingement. AJR Am J Roentgenol. 2019 Nov 06; 1-8.
    View on PubMed
  3. Liao TC, Pedoia V, Neumann J, Link TM, Souza RB, Majumdar S. Extracting Voxel-Based Cartilage Relaxometry Features in Hip Osteoarthritis Subjects Using Principal Component Analysis. J Magn Reson Imaging. 2019 Oct 15.
    View on PubMed
  4. Liao TC, Samaan MA, Popovic T, Neumann J, Zhang AL, Link TM, Majumdar S, Souza RB. Abnormal Joint Loading During Gait in Persons With Hip Osteoarthritis is Associated With Symptoms and Cartilage Lesions. J Orthop Sports Phys Ther. 2019 Oct 14; 1-30.
    View on PubMed
  5. Tibrewala R, Bahroos E, Mehrabian H, Foreman SC, Link TM, Pedoia V, Majumdar S. [18 F]-Sodium Fluoride PET/MR Imaging for Bone-Cartilage Interactions in Hip Osteoarthritis: A Feasibility Study. J Orthop Res. 2019 Aug 19.
    View on PubMed
  6. Jenkins NW, Iriondo C, Shah V, Bahroos E, Ravanfar V, Regan M, Seo Y, Dillon WP, Majumdar S, Talbott JF. Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain. J Vis Exp. 2019 Aug 08; (150).
    View on PubMed
  7. Liao TC, Teng HL, Link TM, Majumdar S, Souza RB. Association Between Gait Kinetics and Symptomatic Progression in Persons With Patellofemoral With/Without Concurrent Tibiofemoral Osteoarthritis. J Orthop Res. 2019 Aug 05.
    View on PubMed
  8. Shah RF, Martinez AM, Pedoia V, Majumdar S, Vail TP, Bini SA. Variation in the Thickness of Knee Cartilage. The Use of a Novel Machine Learning Algorithm for Cartilage Segmentation of Magnetic Resonance Images. J Arthroplasty. 2019 Oct; 34(10):2210-2215.
    View on PubMed
  9. Norman B, Pedoia V, Noworolski A, Link TM, Majumdar S. Applying Densely Connected Convolutional Neural Networks for Staging Osteoarthritis Severity from Plain Radiographs. J Digit Imaging. 2019 Jun; 32(3):471-477.
    View on PubMed
  10. Majumdar S, Lupo J, Vigneron D, Ronen S, Kurhanewicz J, Hess C. In memoriam: Sarah J. Nelson, January 26, 1954-April 3, 2019. Magn Reson Med. 2019 Oct; 82(4):1255-1258.
    View on PubMed
  11. Samaan MA, Zhang AL, Popovic T, Pedoia V, Majumdar S, Souza RB. Hip joint muscle forces during gait in patients with femoroacetabular impingement syndrome are associated with patient reported outcomes and cartilage composition. J Biomech. 2019 Feb 14; 84:138-146.
    View on PubMed
  12. Pedoia V, Majumdar S. Translation of morphological and functional musculoskeletal imaging. J Orthop Res. 2019 Jan; 37(1):23-34.
    View on PubMed
  13. Inamdar G, Pedoia V, Rossi-Devries J, Samaan MA, Link TM, Souza RB, Majumdar S. MR study of longitudinal variations in proximal femur 3D morphological shape and associations with cartilage health in hip osteoarthritis. J Orthop Res. 2019 Jan; 37(1):161-170.
    View on PubMed
  14. Pedoia V, Norman B, Mehany SN, Bucknor MD, Link TM, Majumdar S. 3D convolutional neural networks for detection and severity staging of meniscus and PFJ cartilage morphological degenerative changes in osteoarthritis and anterior cruciate ligament subjects. J Magn Reson Imaging. 2019 02; 49(2):400-410.
    View on PubMed
  15. Grace T, Neumann J, Samaan MA, Souza RB, Majumdar S, Link TM, Zhang AL. Using the Scoring Hip Osteoarthritis with Magnetic Resonance Imaging (SHOMRI) system to assess intra-articular pathology in femoroacetabular impingement. J Orthop Res. 2018 11; 36(11):3064-3070.
    View on PubMed
  16. Neumann J, Zhang AL, Schwaiger BJ, Samaan MA, Souza R, Foreman SC, Joseph GB, Grace T, Majumdar S, Link TM. Validation of scoring hip osteoarthritis with MRI (SHOMRI) scores using hip arthroscopy as a standard of reference. Eur Radiol. 2019 Feb; 29(2):578-587.
    View on PubMed
  17. Grace T, Samaan MA, Souza RB, Link TM, Majumdar S, Zhang AL. Correlation of Patient Symptoms With Labral and Articular Cartilage Damage in Femoroacetabular Impingement. Orthop J Sports Med. 2018 Jun; 6(6):2325967118778785.
    View on PubMed
  18. Cauley JA, Burghardt AJ, Harrison SL, Cawthon PM, Schwartz AV, Connor EB, Ensrud KE, Langsetmo L, Majumdar S, Orwoll E. Accelerated Bone Loss in Older Men: Effects on Bone Microarchitecture and Strength. J Bone Miner Res. 2018 10; 33(10):1859-1869.
    View on PubMed
  19. Rossi-deVries J, Pedoia V, Samaan MA, Ferguson AR, Souza RB, Majumdar S. Using multidimensional topological data analysis to identify traits of hip osteoarthritis. J Magn Reson Imaging. 2018 10; 48(4):1046-1058.
    View on PubMed
  20. Teng HL, Pedoia V, Link TM, Majumdar S, Souza RB. Local associations between knee cartilage T1? and T2 relaxation times and patellofemoral joint stress during walking: A voxel-based relaxometry analysis. Knee. 2018 Jun; 25(3):406-416.
    View on PubMed

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