University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Sharmila Majumdar, PhD

Sharmila Majumdar, PhD

Professor and Vice Chair of Research, Department of Radiology and Biomedical Imaging, UCSF

Cancer Center Program Memberships

Non-aligned

Research Summary

Sharmila Majumdar, PhD, is a UCSF Professor and the Vice Chair of Research in the Department of Radiology and Biomedical Imaging and Professor in the Departments of Bioengineering and Therapeutic Sciences, Orthopedic Surgery at UCSF and Bioengineering at UC Berkeley. She is Director of the Musculoskeletal Research Interest Group at UCSF, an interdisciplinary group consisting of faculty, post-doctoral scholars and students. She obtained her PhD degree in Engineering and Applied Science from Yale University in 1987, where she stayed as a post-doctoral researcher and Assistant Professor until 1989, when she joined UCSF.

Her research work on imaging, particularly magnetic resonance and micro computed tomography, and development of image processing and analysis tools, has been focused in the areas of osteoporosis, osteo-arthritis and lower back pain. Her research, which is supported by grants from the NIH and corporate entities, and is diverse ranging from technical development to clinical trials. She currently heads an NIH Center of Research Translation focused on Osteoarthritis and Imaging, a joint effort between UCSF and UC Davis.

Dr. Majumdar was selected as a fellow of the American Institute of Medical and Biological Engineers in 2004 and a fellow of the International Society of Magnetic Resonance in Medicine in 2008. In 2007 she was awarded the “Excellence in Direct Teaching and/or Excellence in Mentoring and Advising Award” by the UCSF Haile T. Debas Academy of Medical Educators.

She has published extensively in the Journal of Bone Mineral Research, Magnetic Resonance in Medicine, and other highly regarded journals. She also serves as a reviewer and is on the editorial board of scientific journals, and is a recognized expert in the area of imaging.

Education

  • St. Stephens College, University of Delhi, India, B.S., 1983, Physics
  • Yale University, Connecticut, USA, M.S., 1984, Eng. & Applied Physics
  • Yale University, Connecticut, USA, Ph.D., 1987, Eng. & Applied Physics
  • Yale University, Connecticut, USA, Postdoctoral, 1988, Radiology

Professional Experience

  • 2001–present
    Professor, Dept. of Radiology, UCSF
  • 2002–2009
    Member, Division of Bioengineering, UCSF
  • 2002–present
    Professor, Dept. of Bioengineering, UC Berkeley
  • 2003–present
    Director, Musculo-skeletal and Quantitative Imaging Research Group, Dept. of Radiology, UCSF
  • 2003–present
    Member, California Institute for Quantitative Biomedical Research (QB3)
  • 2008–present
    Vice Chair, Dept. of Radiology, UCSF
  • 2009–present
    Joint Faculty Member, Dept. of Bioengineering and Therapeutic Sciences, UCSF

Honors & Awards

  • 2002
    Celebrating Woman Faculty, Award and Recognition, Chancellor and Deans of UCSF
  • 2004
    Fellow of the American Institute of Medical and Biological Engineers (AIMBE)
  • 2008
    Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM)
  • 2016
    Gold Medal of International Society of Magnetic Resonance in Medicine (ISMRM)

Selected Publications

  1. Majumdar S, Lupo J, Vigneron D, Ronen S, Kurhanewicz J, Hess C. In memoriam: Sarah J. Nelson, January 26, 1954-April 3, 2019. Magn Reson Med. 2019 May 17.
    View on PubMed
  2. Samaan MA, Zhang AL, Popovic T, Pedoia V, Majumdar S, Souza RB. Hip joint muscle forces during gait in patients with femoroacetabular impingement syndrome are associated with patient reported outcomes and cartilage composition. J Biomech. 2019 Feb 14; 84:138-146.
    View on PubMed
  3. Pedoia V, Majumdar S. Translation of morphological and functional musculoskeletal imaging. J Orthop Res. 2019 Jan; 37(1):23-34.
    View on PubMed
  4. Inamdar G, Pedoia V, Rossi-Devries J, Samaan MA, Link TM, Souza RB, Majumdar S. MR study of longitudinal variations in proximal femur 3D morphological shape and associations with cartilage health in hip osteoarthritis. J Orthop Res. 2019 Jan; 37(1):161-170.
    View on PubMed
  5. Pedoia V, Norman B, Mehany SN, Bucknor MD, Link TM, Majumdar S. 3D convolutional neural networks for detection and severity staging of meniscus and PFJ cartilage morphological degenerative changes in osteoarthritis and anterior cruciate ligament subjects. J Magn Reson Imaging. 2019 Feb; 49(2):400-410.
    View on PubMed
  6. Norman B, Pedoia V, Noworolski A, Link TM, Majumdar S. Applying Densely Connected Convolutional Neural Networks for Staging Osteoarthritis Severity from Plain Radiographs. J Digit Imaging. 2018 Oct 10.
    View on PubMed
  7. Grace T, Neumann J, Samaan MA, Souza RB, Majumdar S, Link TM, Zhang AL. Using the Scoring Hip Osteoarthritis with Magnetic Resonance Imaging (SHOMRI) system to assess intra-articular pathology in femoroacetabular impingement. J Orthop Res. 2018 Nov; 36(11):3064-3070.
    View on PubMed
  8. Neumann J, Zhang AL, Schwaiger BJ, Samaan MA, Souza R, Foreman SC, Joseph GB, Grace T, Majumdar S, Link TM. Validation of scoring hip osteoarthritis with MRI (SHOMRI) scores using hip arthroscopy as a standard of reference. Eur Radiol. 2019 Feb; 29(2):578-587.
    View on PubMed
  9. Grace T, Samaan MA, Souza RB, Link TM, Majumdar S, Zhang AL. Correlation of Patient Symptoms With Labral and Articular Cartilage Damage in Femoroacetabular Impingement. Orthop J Sports Med. 2018 Jun; 6(6):2325967118778785.
    View on PubMed
  10. Cauley JA, Burghardt AJ, Harrison SL, Cawthon PM, Schwartz AV, Connor EB, Ensrud KE, Langsetmo L, Majumdar S, Orwoll E. Accelerated Bone Loss in Older Men: Effects on Bone Microarchitecture and Strength. J Bone Miner Res. 2018 Oct; 33(10):1859-1869.
    View on PubMed
  11. Rossi-deVries J, Pedoia V, Samaan MA, Ferguson AR, Souza RB, Majumdar S. Using multidimensional topological data analysis to identify traits of hip osteoarthritis. J Magn Reson Imaging. 2018 Oct; 48(4):1046-1058.
    View on PubMed
  12. Teng HL, Pedoia V, Link TM, Majumdar S, Souza RB. Local associations between knee cartilage T1? and T2 relaxation times and patellofemoral joint stress during walking: A voxel-based relaxometry analysis. Knee. 2018 Jun; 25(3):406-416.
    View on PubMed
  13. Norman B, Pedoia V, Majumdar S. Use of 2D U-Net Convolutional Neural Networks for Automated Cartilage and Meniscus Segmentation of Knee MR Imaging Data to Determine Relaxometry and Morphometry. Radiology. 2018 07; 288(1):177-185.
    View on PubMed
  14. Crossley KM, Pandy MG, Majumdar S, Smith AJ, Agricola R, Semciw AI, Kemp JL, Heerey JJ, King MG, Lawrenson PR, Lin YC, Souza RB, Mosler AB, Link TM, Srinivasan R, Schache AG. Femoroacetabular impingement and hip OsteoaRthritis Cohort (FORCe): protocol for a prospective study. J Physiother. 2018 Jan; 64(1):55.
    View on PubMed
  15. Kumar D, Wyatt C, Lee S, Okazaki N, Chiba K, Link TM, Souza RB, Majumdar S. Sagittal plane walking patterns are related to MRI changes over 18-months in people with and without mild-moderate hip osteoarthritis. J Orthop Res. 2018 May; 36(5):1472-1477.
    View on PubMed
  16. Adusumilli G, Joseph SE, Samaan MA, Schultz B, Popovic T, Souza RB, Majumdar S. iPhone Sensors in Tracking Outcome Variables of the 30-Second Chair Stand Test and Stair Climb Test to Evaluate Disability: Cross-Sectional Pilot Study. JMIR Mhealth Uhealth. 2017 Oct 27; 5(10):e166.
    View on PubMed
  17. Samaan MA, Pedoia V, Zhang AL, Gallo MC, Link TM, Souza RB, Majumdar S. A novel mr-based method for detection of cartilage delamination in femoroacetabular impingement patients. J Orthop Res. 2018 03; 36(3):971-978.
    View on PubMed
  18. Pedoia V, Samaan MA, Inamdar G, Gallo MC, Souza RB, Majumdar S. Study of the interactions between proximal femur 3d bone shape, cartilage health, and biomechanics in patients with hip Osteoarthritis. J Orthop Res. 2018 01; 36(1):330-341.
    View on PubMed
  19. Pedoia V, Haefeli J, Morioka K, Teng HL, Nardo L, Souza RB, Ferguson AR, Majumdar S. MRI and biomechanics multidimensional data analysis reveals R2 -R1? as an early predictor of cartilage lesion progression in knee osteoarthritis. J Magn Reson Imaging. 2018 01; 47(1):78-90.
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  20. Amano K, Li AK, Pedoia V, Koff MF, Krych AJ, Link TM, Potter H, Rodeo S, Li X, Ma CB, Majumdar S. Effects of Surgical Factors on Cartilage Can Be Detected Using Quantitative Magnetic Resonance Imaging After Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2017 Apr; 45(5):1075-1084.
    View on PubMed

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