Mack Roach, III, MD

Education

Morehouse College, Atlanta, GA, BS, 1975, Physics
Stanford University School of Medicine, Stanford,CA, MD, 1979, Medicine
University of California San Francisco, Fellow, 1981-83, Med Oncology
Stanford University School of Medicine, Stanford,CA, Resident, 1984-87, Radiation Oncology

Honors & Awards

• 1980-1981
  Outstanding Intern of the Year (Charles R. Drew Award)
• 1981-1982
  Fellow of the American Cancer Society
• 1994
  UCSF Health Net Wellness Award
• 1994-1997
  American Cancer Society Career Development Award
• 1996-97; 1997-98; 2001-02
  "The Best Doctors in America"
• 2002
  Fellow, American College of Radiology
• 2002-05
  President, John Hale Medical Society
• 2005
  10 Most Influential African Americans in the Bay Area (Healthcare)

Selected Publications

1. Hamstra DA, Dignam JJ, Bruner DW, Michaelson MD, Bachand F, Master V, Torres MA, Saylor PJ, Wallace RE, Vapiwala N, Efstathiou JA, Roach M, Rosenthal SA, Raben A, Morgan SC, Kavadi VS, Spratt DE, Michalski JM, Seiferheld W, Pugh SL, Movsas B, Sandler H Phase 3 Trial of Dose-Escalated Radiation Therapy and Standard Androgen Deprivation Therapy Versus Dose-Escalated Radiation Therapy and Enhanced Androgen Deprivation Therapy With Orteronel for Men With High-Risk Prostate Cancer (NRG/RTOG 1115).  View on PubMed
2. Roy S, Sun Y, Eastham JA, Gleave M, Wallis CJD, Beltran HA, Kishan AU, Jia AY, Zaorsky NG, Nagar H, Garcia JA, Small EJ, Nguyen P, Attard G, McKay RR, Sartor O, Berlin A, Rosenthal SA, Halabi S, Vince R, Ponsky L, Morgan SC, Hannan R, Raben A, Roach M, Michalski JM, Morris MJ, Sandler HM, Spratt DE Radiotherapy- Versus Surgery-based Treatment Strategy in High-risk Prostate Cancer.  View on PubMed
3. Roach M, Zhang J, Mohamad O, van der Wal D, Simko JP, DeVries S, Huang HC, Joun S, Schaeffer EM, Morgan TM, Keim-Malpass J, Chen E, Yamashita R, Monson JM, Naz F, Wallace J, Bahary JP, Wilke D, Batra S, Biedermann GB, Faria S, Hwang L, Sandler HM, Spratt DE, Pugh SL, Esteva A, Tran PT, Feng FY. Assessing Algorithmic Fairness With a Multimodal Artificial Intelligence Model in Men of African and Non-African Origin on NRG Oncology Prostate Cancer Phase III Trials. JCO Clin Cancer Inform. 2025 May; 9:e2400284.  View on PubMed
4. Moul JW, Boldt-Houle DM, Roach M. Real-world analyses of major adverse cardiovascular events and mortality risk after androgen deprivation therapy initiation in black vs. white prostate cancer patients. Prostate Cancer Prostatic Dis. 2025 Apr 18.  View on PubMed
5. Ogunsanya ME, Kaninjing E, DeForge SM, Morton DJ, Cole P, Beckford P, Reese D, Mitchell T, Montgomery E, Odeleye R, Miró-Rivera EY, Roberts K, Neil JM, Alexander AC, Funk-Lawler RK, Azizoddin D, Roach M, Washington SL, Dwyer K, Young ME, Odedina FT, Kendzor DE. Bridging the Gap: Enhancing Prostate Cancer Survivorship and Advocacy Among Ethnically Diverse Black Men Through Community Town Halls. J Cancer Educ. 2025 Feb 24.  View on PubMed
6. Roach M, Ling S, Coleman PW. MRI-Linac-Based Radiotherapy-Promising or Hype? JAMA Oncol. 2024 Oct 01; 10(10):1313-1314.  View on PubMed
7. Mohamad O, Li YR, Feng F, Hong JC, Wong A, El Kouzi Z, Shelan M, Zilli T, Carroll P, Roach M. Delayed definitive management of localized prostate cancer: what do we know? Prostate Cancer Prostatic Dis. 2024 Aug 11.  View on PubMed
8. Roach M. Pragmatic clinical trials for localized prostate cancer: lessons learned and "three sins". Front Oncol. 2024; 14:1379306.  View on PubMed
9. Schaeffer EM, Srinivas S, Adra N, An Y, Bitting R, Chapin B, Cheng HH, D'Amico AV, Desai N, Dorff T, Eastham JA, Farrington TA, Gao X, Gupta S, Guzzo T, Ippolito JE, Karnes RJ, Kuettel MR, Lang JM, Lotan T, McKay RR, Morgan T, Pow-Sang JM, Reiter R, Roach M, Robin T, Rosenfeld S, Shabsigh A, Spratt D, Szmulewitz R, Teply BA, Tward J, Valicenti R, Wong JK, Snedeker J, Freedman-Cass DA. NCCN Guidelines® Insights: Prostate Cancer, Version 3.2024. J Natl Compr Canc Netw. 2024 04; 22(3):140-150.  View on PubMed
10. Mmonu N, Kamdar N, Roach M, Sarma A, Makarov D, Zabar S, Breyer B Disparities in the Delivery of Prostate Cancer Survivorship Care in the USA: A Claims-based Analysis of Urinary Adverse Events and Erectile Dysfunction Among Prostate Cancer Survivors.  View on PubMed
11. Black S, Roach M, Rappuoli R Primary cancer prevention for cancers with no known infectious etiology: Time for a new paradigm.  View on PubMed
12. Mak KS, Scannell Bryan M, Dignam JJ, Shipley WU, Lin Y, Peters CA, Gore EM, Rosenthal SA, Zeitzer KL, D'Souza DP, Horwitz EM, Pisansky TM, Maier JM, Chafe SM, Robin TP, Roach M, Tran PT, Souhami L, Michalski JM, Hartford AC, Feng FY, Sandler HM, Efstathiou JA. Cardiovascular Mortality and Duration of Androgen Deprivation in Locally Advanced Prostate Cancer: Long-term Update of NRG/RTOG 9202. Eur Urol Focus. 2024 Mar; 10(2):271-278.  View on PubMed
13. Coleman CN, Wong R, Petereit DG, Maguire PD, Heron DE, Steinberg M, Bains Y, Vikram B, Angelis P, Livinski AA, Roach M, Govern FS. The National Cancer Institute's Cancer Disparities Research Partnership Program: a unique funding model 20 years later. J Natl Cancer Inst. 2023 12 06; 115(12):1465-1474.  View on PubMed
14. Roach M, Coleman PW, Kittles R. Prostate Cancer, Race, and Health Disparity: What We Know. Cancer J. 2023 Nov-Dec 01; 29(6):328-337.  View on PubMed
15. Shaheen H, Salans MA, Mohamad O, Coleman PW, Ahmed S, Roach M. Age 70 +/- 5 Years and Cancer-Specific Outcomes After Treatment of Localized Prostate Cancer: A Systematic Review. Int J Radiat Oncol Biol Phys. 2024 Mar 01; 118(3):672-681.  View on PubMed
16. Schaeffer EM, Srinivas S, Adra N, An Y, Barocas D, Bitting R, Bryce A, Chapin B, Cheng HH, D'Amico AV, Desai N, Dorff T, Eastham JA, Farrington TA, Gao X, Gupta S, Guzzo T, Ippolito JE, Kuettel MR, Lang JM, Lotan T, McKay RR, Morgan T, Netto G, Pow-Sang JM, Reiter R, Roach M, Robin T, Rosenfeld S, Shabsigh A, Spratt D, Teply BA, Tward J, Valicenti R, Wong JK, Shead DA, Snedeker J, Freedman-Cass DA. Prostate Cancer, Version 4.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023 10; 21(10):1067-1096.  View on PubMed
17. Roach M, Chapman C, Coleman PW. Racism Might Cause Prostate Cancer and Definitely Causes Excess Unemployment, Lost Wages, and Excess Cancer Deaths. J Clin Oncol. 2023 10 01; 41(28):4595-4597.  View on PubMed
18. Michalski JM, Winter KA, Prestidge BR, Sanda MG, Amin M, Bice WS, Gay HA, Ibbott GS, Crook JM, Catton CN, Raben A, Bosch W, Beyer DC, Frank SJ, Papagikos MA, Rosenthal SA, Barthold HJ, Roach M, Moughan J, Sandler HM. Effect of Brachytherapy With External Beam Radiation Therapy Versus Brachytherapy Alone for Intermediate-Risk Prostate Cancer: NRG Oncology RTOG 0232 Randomized Clinical Trial. J Clin Oncol. 2023 08 20; 41(24):4035-4044.  View on PubMed
19. Sabbagh A, Washington SL, Tilki D, Hong JC, Feng J, Valdes G, Chen MH, Wu J, Huland H, Graefen M, Wiegel T, Böhmer D, Cowan JE, Cooperberg M, Feng FY, Roach M, Trock BJ, Partin AW, D'Amico AV, Carroll PR, Mohamad O. Development and External Validation of a Machine Learning Model for Prediction of Lymph Node Metastasis in Patients with Prostate Cancer. Eur Urol Oncol. 2023 Oct; 6(5):501-507.  View on PubMed
20. Esteva A, Feng J, van der Wal D, Huang SC, Simko JP, DeVries S, Chen E, Schaeffer EM, Morgan TM, Sun Y, Ghorbani A, Naik N, Nathawani D, Socher R, Michalski JM, Roach M, Pisansky TM, Monson JM, Naz F, Wallace J, Ferguson MJ, Bahary JP, Zou J, Lungren M, Yeung S, Ross AE, NRG Prostate Cancer AI Consortium, Sandler HM, Tran PT, Spratt DE, Pugh S, Feng FY, Mohamad O. Author Correction: Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials. NPJ Digit Med. 2023 Feb 22; 6(1):27.  View on PubMed

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