University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Nelson Schiller, MD, FACC

Nelson Schiller, MD, FACC

Professor in Residence, Department of Medicine (Cardiology), UCSF

Cancer Center Program Memberships

Affiliate Member

Research Summary

CLINICAL INTERESTS: Dr. Nelson B. Schiller is a cardiologist who specializes in the use of echocardiography in the diagnosis and treatment of heart disease. He is the founder of the UCSF Echocardiography Laboratory and the UCSF Adult Congenital Heart Disease Clinic. He has played an integral role in the development of many diagnostic and treatment techniques including two dimensional echocardiography, transesophogeal echocardiography, Doppler pulmonary pressure determination, myocardial contrast perfusion and echocardiography phase imaging for ventricular coordination. In the areas of structural heart disease, he is an expert in the treatment of mitral and aortic valve diseases, hypertrophic cardiomyopathy and congenital heart diseases.

RESEARCH INTERESTS: In collaboration with his colleagues, Schiller is involved in research in quantitation of cardiac function and structure, the biology and function of the left atrium, exercise physiology and hemodynamics in heart disease, body composition in heart disease, adult congenital heart disease, three-dimensional reconstruction, echocardiographic contrast agents for quantitation and myocardial perfusion, transesophageal echocardiography, physiology of renal disease, and outcomes in coronary disease as predicted by quantitative phenotyping,


Union College, Schenectady, New York, BS, 1962
State University of New York at Buffalo, Buffalo NY, MD, 1966
Medical Intern, Ochsner Medical Foundation, New Orleans, LA, 1966-1967
Medical Resident, University of California at San Diego, CA, 1967-1971
USPHS Clinical Cardiology Trainee, University of California at San Francisco, CA, 1971-1973

Professional Experience

  • 1973-1975
    Assistant Clinical Professor of Medicine, School of Medicine, UCSF
  • 1973
    Founder and Director, Cardiac Noninvasive Laboratories, Dept. of Medicine, Cardiovascular Division, Moffitt Hospital, UCSF
  • 1978-1997
    Co-Director and Director, Cardiac Noninvasive Laboratories, Dept. of Medicine, Cardiovascular Division, Moffitt Hospital, UCSF
  • 1975-1978
    Assistant Professor of Medicine-in-Residence, UCSF
  • 1978
    Assistant Professor of Radiology-in-Residence, UCSF
  • 1977-1981
    Scientific Staff, Cardiovascular Research Institute
  • 1980-1986
    Associate Professor of Medicine in Residence, UCSF
  • 1985-1997
    Founder and Director, Adult Congenital Heart Disease Clinic, UCSF, Ambulatory Care Center
  • 1986-present
    Professor of Medicine in Residence, UCSF
  • 1986-present
    Professor of Radiology in Residence, UCSF
  • 1992-present
    Professor of Anethesia in Residence, UCSF
  • 1997-1998
    Preceptor to Physcian Assistant/Nurse Practitioner students, Stanfod Unviersity School of Medicine Primary Care Association Program and the Division of Family and Community Medicine
  • 1977-present
    UCSF Faculty Association Board of Directors
  • 1997-2002
    Director, Echocardiography Laboratory, San Francisco Veterans Affairs Medical Center
  • 2002-present
    Director of Echocardiography Research, San Francisco Veterans Affairs Medical Center

Honors & Awards

  • 1966
    Thesis Honors, State University of New York at Buffalo, School of Medicine
  • 1981
    Honorary Member, Venezuelan Society of Cardiology, Elected May 29, 1981
  • 1982
    Gustav Nylin Lecturer, Swedish Society of Medical Sciences, Stockholm
  • 1/21/1983
    Commendation by UC President Saxon and by UCSF Chancellor Krevans for Development of Intraoperative Transesophageal Echocardiography in "A Report to the Regents"
  • 4/5/1991
    Karolinska Institute, Stockholm - Thesis opponent
  • 1994-1998
    The Best Doctors in America (Pacific Region)
  • 1997, 1998, 1999
    The Best Doctors in San Francisco, San Francisco Focus Magazine, San Francisco Chronicle and Examiner
  • 1997-98
    UCSF Clinical Cardiology Fellows Award for Outstanding Teacher

Selected Publications

  1. Mishra RK, Tison GH, Fang Q, Scherzer R, Whooley MA, Schiller NB. Association of Machine Learning-Derived Phenogroupings of Echocardiographic Variables with Heart Failure in Stable Coronary Artery Disease: The Heart and Soul Study. J Am Soc Echocardiogr. 2020 Jan 13.
    View on PubMed
  2. Desai YB, Mishra RK, Fang Q, Whooley MA, Schiller NB. Association of Longitudinal Change in High-Sensitivity Troponin with All-Cause Mortality in Coronary Artery Disease: The Heart and Soul Study. Cardiology. 2020 Jan 07; 1-8.
    View on PubMed
  3. Abuzaid A, Cohen BE, Pursnani S, Lahsaeizadeh S, Ristow B, Shaw RE, Rosenblatt A, Fang Q, Schiller NB. Who is young at heart and when? Diastolic Doppler data from the mind your heart study. Echocardiography. 2019 09; 36(9):1744-1746.
    View on PubMed
  4. Papolos AI, Schiller NB, Belzer A, Zhuo H, Gotts JE, Bibby D, Calfee CS, Matthay MA. Pulmonary Dead Space Monitoring: Identifying Subjects With ARDS at Risk of Developing Right Ventricular Dysfunction. Respir Care. 2019 Sep; 64(9):1101-1108.
    View on PubMed
  5. Ranjan R, Mostafavi Toroghi H, Pressman GS, Schiller NB. Doppler Recognition of Low or Normal Central Venous Pressure from Continuous Flow from Inferior Vena Cava Into Right Atrium. Am J Cardiol. 2019 Aug 01; 124(3):448-452.
    View on PubMed
  6. Meisel K, Yuan K, Fang Q, Bibby D, Lee R, Schiller NB. Embolic Stroke of Undetermined Source: A Population with Left Atrial Dysfunction. J Stroke Cerebrovasc Dis. 2019 Jul; 28(7):1891-1896.
    View on PubMed
  7. Papolos A, Fan E, Wagle RR, Foster E, Boyle AJ, Yeghiazarians Y, MacGregor JS, Grossman W, Schiller NB, Ganz P, Tison GH. Echocardiographic determination of pulmonary arterial capacitance. Int J Cardiovasc Imaging. 2019 Sep; 35(9):1581-1586.
    View on PubMed
  8. Ermakov S, Gulhar R, Lim L, Bibby D, Fang Q, Nah G, Abraham TP, Schiller NB, Delling FN. Left ventricular mechanical dispersion predicts arrhythmic risk in mitral valve prolapse. Heart. 2019 Jul; 105(14):1063-1069.
    View on PubMed
  9. Simpson TF, Tyler JM, Thomas RC, Fang Q, Bibby D, Schiller NB. Mitral annular peak systolic and diastolic velocities are characteristic of healthy hearts: A Doppler tissue imaging study. Echocardiography. 2019 03; 36(3):433-438.
    View on PubMed
  10. Dubin RF, Whooley M, Pico A, Ganz P, Schiller NB, Meyer C. Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study. PLoS One. 2018; 13(12):e0208042.
    View on PubMed
  11. Fitzpatrick JK, Meyer CS, Schiller NB, Whooley MA, Mishra RK. Ventricular-Vascular Coupling at Rest and after Exercise Is Associated with Heart Failure Hospitalizations in Patients With Coronary Artery Disease. J Am Soc Echocardiogr. 2018 11; 31(11):1212-1220.e3.
    View on PubMed
  12. Ranjan R, Valez EM, Haldipur A, Schiller NB. Relation of Velocity-Time Integral of the Left Ventricular Outflow Tract to that of the Descending Thoracic Aorta and Usefulness of a Fixed Ratio for Internal Validation. Am J Cardiol. 2018 07 01; 122(1):166-169.
    View on PubMed
  13. Sardana M, Lessard D, Tsao CW, Parikh NI, Barton BA, Nah G, Thomas RC, Cheng S, Schiller NB, Aragam JR, Mitchell GF, Vaze A, Benjamin EJ, Vasan RS, McManus DD. Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study. J Am Heart Assoc. 2018 03 30; 7(7).
    View on PubMed
  14. Rudski LG, Gargani L, Armstrong WF, Lancellotti P, Lester SJ, Grünig E, D'Alto M, Åström Aneq M, Ferrara F, Saggar R, Saggar R, Naeije R, Picano E, Schiller NB, Bossone E. Stressing the Cardiopulmonary Vascular System: The Role of Echocardiography. J Am Soc Echocardiogr. 2018 05; 31(5):527-550.e11.
    View on PubMed
  15. Fitzpatrick JK, Cohen BE, Rosenblatt A, Shaw RE, Schiller NB. Usefulness of Epicardial Area in the Short Axis to Identify Elevated Left Ventricular Mass in Men. Am J Cardiol. 2018 06 15; 121(12):1639-1644.
    View on PubMed
  16. Psotka MA, Schiller NB, Whooley MA, Mishra RK. Association of change in 5-year N-terminal fragment of the prohormone brain-type natriuretic peptide with left ventricular structure and function in stable coronary disease. J Cardiovasc Med (Hagerstown). 2018 Feb; 19(2):67-72.
    View on PubMed
  17. Sardana M, Nah G, Tsao CW, Ogunsua AA, Vittinghoff E, Thomas RC, Cheng S, Vaze A, Aragam JR, Mitchell GF, Benjamin EJ, Vasan RS, Aurigemma GP, Schiller NB, McManus DD, Parikh NI. Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study. J Am Soc Echocardiogr. 2017 Sep; 30(9):904-912.e2.
    View on PubMed
  18. Yuan N, Geha RM, Schiller NB. A Change of Pace: Sudden Hypotension. Am J Med. 2017 Jul; 130(7):799-801.
    View on PubMed
  19. Zhao SX, Soltanzad N, Swaminathan A, Ogden WD, Schiller NB. Frequency and Associated Clinical Features of Functional Tricuspid Regurgitation in Patients With Chronic Atrial Fibrillation. Am J Cardiol. 2017 05 01; 119(9):1371-1377.
    View on PubMed
  20. Wang EY, Dixson J, Schiller NB, Whooley MA. Causes and Predictors of Death in Patients With Coronary Heart Disease (from the Heart and Soul Study). Am J Cardiol. 2017 Jan 01; 119(1):27-34.
    View on PubMed

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