Research Summary

Dr. Jess Scholey is an Assistant Professor, Physics Director of the MRI Simulation Program, and Physics Lead of the Proton Ocular Program in the Department of Radiation Oncology at the University of California, San Francisco. She received her BA in Physics from UC Berkeley and went on to receive her MSc and clinical residency training in medical physics from The University of Pennsylvania. Upon completion of her clinical training and ABR certification, she received her PhD from the Joint UC Berkeley-UCSF Bioengineering Program. She joined the faculty in 2017 and focuses on radiation oncology applications of MRI, proton therapy, and deep learning using medical imaging. Dr. Scholey leads the educational curriculum of MRI and proton therapy in the Department of Radiation Oncology and is an active member of the American Association of Physicists in Medicine, International Society for Magnetic Resonance in Medicine, Particle Therapy Co-Operative Group, and the UCSF Center for Intelligent Imaging.


2022 - Diversity, Equity, and Inclusion Champion Training, The University of California
PhD, 2021 - Bioengineering, The University of California
M.S., 2015 - Medical Physics, The University of Pennsylvania
B.A, 2012 - Physics, The University of California, Berkeley

Selected Publications

  1. Chang CW, Marants R, Gao Y, Goette M, Scholey JE, Bradley JD, Liu T, Zhou J, Sudhyadhom A, Yang X. Multimodal Imaging-based material mass density estimation for Proton therapy using supervised deep learning. Br J Radiol. 2023 Sep 03; 20220907.  View on PubMed
  2. Marants R, Tattenberg S, Scholey J, Kaza E, Miao X, Benkert T, Magneson O, Fischer J, Vinas L, Niepel K, Bortfeld T, Landry G, Parodi K, Verburg J, Sudhyadhom A. Validation of an MR-based multimodal method for molecular composition and proton stopping power ratio determination using ex vivo animal tissues and tissue-mimicking phantoms. Phys Med Biol. 2023 08 28; 68(17).  View on PubMed
  3. Jiao C, Ling D, Bian S, Vassantachart A, Cheng K, Mehta S, Lock D, Zhu Z, Feng M, Thomas H, Scholey JE, Sheng K, Fan Z, Yang W. Contrast-Enhanced Liver Magnetic Resonance Image Synthesis Using Gradient Regularized Multi-Modal Multi-Discrimination Sparse Attention Fusion GAN. Cancers (Basel). 2023 Jul 08; 15(14).  View on PubMed
  4. Claessens M, Oria CS, Brouwer CL, Ziemer BP, Scholey JE, Lin H, Witztum A, Morin O, Naqa IE, Van Elmpt W, Verellen D. Quality Assurance for AI-Based Applications in Radiation Therapy. Semin Radiat Oncol. 2022 10; 32(4):421-431.  View on PubMed
  5. Scholey JE, Rajagopal A, Vasquez EG, Sudhyadhom A, Larson PEZ. Generation of synthetic megavoltage CT for MRI-only radiotherapy treatment planning using a 3D deep convolutional neural network. Med Phys. 2022 Oct; 49(10):6622-6634.  View on PubMed
  6. Scholey J, Vinas L, Kearney V, Yom S, Larson PEZ, Descovich M, Sudhyadhom A. Improved accuracy of relative electron density and proton stopping power ratio through CycleGAN machine learning. Phys Med Biol. 2022 05 02; 67(10).  View on PubMed
  7. Scholey JE, Chandramohan D, Naren T, Liu W, Larson PEZ, Sudhyadhom A. Technical Note: A methodology for improved accuracy in stopping power estimation using MRI and CT. Med Phys. 2021 Jan; 48(1):342-353.  View on PubMed
  8. Mishra KK, Scholey JE, Daftari IK, Afshar A, Tsai T, Park S, Quivey JM, Char DH. Oral isotretinoin and topical retinoid use in a series of young patients with ocular melanoma. Am J Ophthalmol Case Rep. 2020 Sep; 19:100787.  View on PubMed
  9. Mishra KK, Afshar A, Thariat J, Shih HA, Scholey JE, Daftari IK, Kacperek A, Pica A, Hrbacek J, Dendale R, Mazal A, Heufelder J, Char DH, Sauerwein WAG, Weber DC, Damato BE. Practice Considerations for Proton Beam Radiation Therapy of Uveal Melanoma During the Coronavirus Disease Pandemic: Particle Therapy Co-Operative Group Ocular Experience. Adv Radiat Oncol. 2020 Jul-Aug; 5(4):682-686.  View on PubMed
  10. Lin LL, Kirk M, Scholey J, Taku N, Kiely JB, White B, Both S. Initial Report of Pencil Beam Scanning Proton Therapy for Posthysterectomy Patients With Gynecologic Cancer. Int J Radiat Oncol Biol Phys. 2016 May 01; 95(1):181-189.  View on PubMed
  11. Scholey JE, Nithianantham S, Scholey JM, Al-Bassam J. Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers. Elife. 2014 Apr 08; 3:e02217.  View on PubMed

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