Research Summary

I am a physician scientist in the Departments of Radiation Oncology and Neurological Surgery. My clinical expertise is providing radiotherapy for children and adults with nervous system cancers. My scientific focus is understanding oncogenic growth factor signaling through receptor tyrosine kinases and the Ras signaling pathway with an emphasis on neurofibromatosis and nervous system tumors to identify better treatments for patients.

Research Funding

  • July 11, 2022 - June 30, 2025 - , Principal Investigator . Sponsor: Neurofibromatosis Therapeutic Acceleration Program, Sponsor Award ID: Francis Collins Scholar

Education

2022 - Radiation Oncology, UCSF
2018 - Internal Medicine, California Pacific Medical Center
MD, PhD, 2017 - Medicine, Neuroscience, Mount Sinai School of Medicine
B.S., 2009 - Biology, California Institute of Technology

Honors & Awards

  • 2017
    SNO Adult Basic Research Abstract Award, Society for Neuro-Oncology
  • 2018
    Graduate Medical Education Research Day Best Poster Award, CPMC
  • 2019-2020
    UCSF Wolfe Meningioma Program Project Fellowship, UCSF
  • 2019-2021
    Children’s Tumor Foundation Young Investigator Award, UCSF
  • 2021 ASTRO
    Annual Meeting Resident Abstract Award, American Society for Radiation Oncology
  • 2021
    Top Peripheral Nerve Paper of the Year, Congress of Neurological Surgeons
  • 2021
    SNO Young Investigator Forum Award Winner, Society for Neuro-Oncology
  • 2020-2022
    Holman Pathway Research Fellowship, American Board of Radiology
  • 2022
    Roentgen Resident/Fellow Research Award, Radiological Society of North America
  • 2022-2025
    Francis Collins Scholar Award, Neurofibromatosis Therapeutic Acceleration Program

Selected Publications

  1. Vasudevan HN, Choudhury A, Hilz S, Villanueva-Meyer JE, Chen WC, Lucas CG, Braunstein SE, Oberheim Bush NA, Butowski N, Pekmezci M, McDermott MW, Perry A, Solomon DA, Magill ST, Raleigh DR. Intratumor and informatic heterogeneity influence meningioma molecular classification. Acta Neuropathol. 2022 09; 144(3):579-583.  View on PubMed
  2. Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet. 2022 05; 54(5):649-659.  View on PubMed
  3. Driver J, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M, Aizer AA, Alexander BM, Ligon KL, Reardon DA, Wen PY, Al-Mefty O, Ligon AH, Dubuc AM, Beroukhim R, Claus EB, Dunn IF, Santagata S, Linda Bi W. A molecularly integrated grade for meningioma. Neuro Oncol. 2022 05 04; 24(5):796-808.  View on PubMed
  4. Chen WC, Lafreniere M, Phuong C, Liu SJ, Baal JD, Lometti M, Morin O, Ziemer B, Vasudevan HN, Lucas CG, Hervey-Jumper SL, Theodosopoulos PV, Magill ST, Fogh S, Nakamura JL, Boreta L, Sneed PK, McDermott MW, Raleigh DR, Braunstein SE. Resection with intraoperative cesium-131 brachytherapy as salvage therapy for recurrent brain tumors. J Neurosurg. 2022 Jan 21; 1-7.  View on PubMed
  5. Ahmad TR, Vasudevan HN, Lazar AA, Chan JW, George JR, Alvarado MD, Yu SS, Daud A, Yom SS. Should Sentinel Lymph Node Biopsy Status Guide Adjuvant Radiation Therapy in Patients With Merkel Cell Carcinoma? Adv Radiat Oncol. 2021 Nov-Dec; 6(6):100764.  View on PubMed
  6. Sun C, Liu L, Vasudevan HN, Chang KC, Abate AR. Accurate Bulk Quantitation of Droplet Digital Polymerase Chain Reaction. Anal Chem. 2021 07 27; 93(29):9974-9979.  View on PubMed
  7. Wu SY, Yee E, Vasudevan HN, Fogh SE, Boreta L, Braunstein SE, Hong JC. Risk Stratification for Imminent Risk of Death at the Time of Palliative Radiotherapy Consultation. JAMA Netw Open. 2021 07 01; 4(7):e2115641.  View on PubMed
  8. Vasudevan HN, Yom SS. Nasopharyngeal Carcinoma and Its Association with Epstein-Barr Virus. Hematol Oncol Clin North Am. 2021 10; 35(5):963-971.  View on PubMed
  9. Susko MS, Chen WC, Vasudevan HN, Magill ST, Lucas CG, Oberheim Bush NA, Solomon DA, Theodosopoulos PV, McDermott MW, Villanueva-Meyer JE, Boreta L, Nakamura JL, Sneed PK, Braunstein SE, Raleigh DR. Letter: Patterns of Intermediate- and High-Risk Meningioma Recurrence After Treatment With Postoperative External Beam Radiotherapy. Neurosurgery. 2021 06 15; 89(1):E99-E101.  View on PubMed
  10. Demaree B, Delley CL, Vasudevan HN, Peretz CAC, Ruff D, Smith CC, Abate AR. Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia. Nat Commun. 2021 03 11; 12(1):1583.  View on PubMed
  11. Sun C, Liu L, Vasudevan HN, Chang KC, Abate AR. Accurate bulk quantitation of droplet digital PCR. bioRxiv. 2021 Jan 15.  View on PubMed
  12. Vasudevan HN, Lucas CG, Villanueva-Meyer JE, Theodosopoulos PV, Raleigh DR. Genetic Events and Signaling Mechanisms Underlying Schwann Cell Fate in Development and Cancer. Neurosurgery. 2021 01 13; 88(2):234-245.  View on PubMed
  13. Vasudevan HN, Xu P, Servellita V, Miller S, Liu L, Gopez A, Chiu CY, Abate AR. Digital droplet PCR accurately quantifies SARS-CoV-2 viral load from crude lysate without nucleic acid purification. Sci Rep. 2021 01 12; 11(1):780.  View on PubMed
  14. Chen WC, Vasudevan HN, Choudhury A, Pekmezci M, Lucas CG, Phillips J, Magill ST, Susko MS, Braunstein SE, Oberheim Bush NA, Boreta L, Nakamura JL, Villanueva-Meyer JE, Sneed PK, Perry A, McDermott MW, Solomon DA, Theodosopoulos PV, Raleigh DR. A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection. Neurosurgery. 2020 12 15; 88(1):202-210.  View on PubMed
  15. Lucas CG, Vasudevan HN, Chen WC, Magill ST, Braunstein SE, Jacques L, Dahiya S, Rodriguez FJ, Horvai AE, Perry A, Pekmezci M, Raleigh DR. Histopathologic findings in malignant peripheral nerve sheath tumor predict response to radiotherapy and overall survival. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa131.  View on PubMed
  16. Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR. Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma. Nat Commun. 2020 09 23; 11(1):4803.  View on PubMed
  17. Vasudevan H, Xu P, Servellita V, Miller S, Liu L, Gopez A, Chiu CY, Abate AR. Digital droplet PCR accurately quantifies SARS-CoV-2 viral load from crude lysate without nucleic acid purification. medRxiv. 2020 Sep 03.  View on PubMed
  18. Prager BC, Vasudevan HN, Dixit D, Bernatchez JA, Wu Q, Wallace LC, Bhargava S, Lee D, King BH, Morton AR, Gimple RC, Pekmezci M, Zhu Z, Siqueira-Neto JL, Wang X, Xie Q, Chen C, Barnett GH, Vogelbaum MA, Mack SC, Chavez L, Perry A, Raleigh DR, Rich JN. The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies. Cancer Discov. 2020 11; 10(11):1722-1741.  View on PubMed
  19. Vasudevan HN, Yom SS. Combining Systemic Therapy With Radiation: Head and Neck Cancer Treatments in an Era of Targeted Agents and Immunotherapy. J Natl Compr Canc Netw. 2020 07; 18(7):907-913.  View on PubMed
  20. Vasudevan HN, Castro MRH, Lee JC, Villanueva-Meyer JE, Bush NAO, McDermott MW, Solomon DA, Perry A, Magill ST, Raleigh DR. DNA methylation profiling demonstrates superior diagnostic classification to RNA-sequencing in a case of metastatic meningioma. Acta Neuropathol Commun. 2020 06 09; 8(1):82.  View on PubMed

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