Saturday, APRIL 26th

METHODS WORKSHOPS
Session MW10 - Statistics Made Simple, Engaging, and Practical: A Primer for Non-Statisticians
April 26, 2025, 12:30 - 2:00 PM     Room S405 - McCormick Pl South (Level 4)
1:00 PM - 1:20 PM    Boosting the quality and impact of preclinical studies through the power of statistics
Mi-Ok Kim, PhD, MS, MA UCSF  

Session MW02 - Application of AI and Natural Language Processing to Advance Cancer Research and Treatment 
April 26, 2025, 1:00 PM - 1:20 PM     Room S100 BC (Grand Ballroom BC) - McCormick Place South (Level 1)
1:00 PM - 1:20 PM    - Utilization of language models for medical information retrieval
Travis Zack, MD, PhD UCSF

ED SESSION
Session ED44 - Theranostics: The Nuts and Bolts
April 26, 2025, 2:30 PM - 4:00 PM     Room S401 - McCormick PlSouth (Level 4)
3:05 PM - 3:30 PM    - Evolving role of translational and clinical theranostics
Robert Flavell, PhD UCSF

Sunday, APRIL 27th

OPENING PLENARY SESSION
Session PL02 - Opening Plenary: Unifying Cancer Science and Medicine—A Continuum of Innovation for Impact
April 27, 2025, 9:30 AM - 11:30 AM     Hall B1 - McCormick PlNorth (Level 3)
9:40 AM - 10:07 AM    - Overcoming the undruggable nature of the most common human oncogene, K-Ras
Kevan M. Shokat, PhD  UCSF

MAJOR SYMPOSIUM - Tumor Biology
SESSION SY42 - Tissue Mechanics and Physical Forces in Cancer
April 27, 2025, 1:00 - 2:30 PM     Room E450 A - McCormick Lakeside Center (Level 4)
1:30 PM - 1:50 PM    - Forcing cancer initiation and progression through myeloid lipid peroxidation-mediated DNA damage
Valerie M. Weaver, PhD. UCSF    

CLINICAL TRIALS PLENARY SESSION
SESSION CTPL01 - Advances in Immunotherapy
April 27, 2025, 1:00 PM - 3:00 PM     Arie Crown Theater - McCormick Lakeside (Level 2)
2:45 PM - 2:55 PM    - Discussant
Pamela N. Munster, MD. UCSF 

MINISYMPOSIUM – Clinical Research
MS.CL01.01 - Liquid Biopsy: Circulating Tumor Cells
April 27, 2025, 3:00 PM - 5:00 PM     Room E451 - McCormick Lakeside Center (Level 4)
3:50 PM - 4:05 PM    1147 - Development of a novel assay to detect circulating tumor cells in the cerebrospinal fluid of patients with leptomeningeal disease
Laura A. Huppert, MD  UCSF

CLINICAL TRIALS PLENARY SESSION
CTPL02 - New Frontiers in Precision Oncology
April 27, 2025, 3:30 PM - 5:30 PM     Arie Crown Theater - McCormick Lakeside (Level 2)
5:15 PM - 5:25 PM    - Discussant
Trever G. Bivona, MD, PhD  UCSF 

TOWN MEETING
Session TM07 - Charting the Trajectory for Advancements in Pediatric Cancer Research- A Pediatric Cancer Working Group Town Hall
April 27, 2025, 6:30 - 8:30 PM     Room S103 - McCormick PlSouth (Level 1)
7:00 PM - 7:10 PM    - Chair
Alejandro Sweet-Cordero, MD  UCSF 

Monday, APRIL 28th

MAJOR SYMPOSIUM     Molecular/Cellular Biology and Genetics
Session SY26 - Metabolism and Organelle Biology in Cancer
April 28, 2025, 10:15 AM - 11:45 AM     Location to be announced
10:15 AM - 10:16 AM    - Chairperson
Rushika M. Perera. UCSF 
11:20 AM - 11:35 AM    - Decoding novel lysosome functions in pancreatic cancer
Rushika M. Perera, PhD. UCSF 

MAJOR SYMPOSIUM     Chemistry, Drug Dev, Clinical Research
Session SY08 - Developments in RAS Signaling Inhibition: Bench to Bedside
April 28, 2025, 12:30 PM - 2:00 PM     Location to be announced
12:30 PM - 12:31 PM    - Chairperson & Presentation
12:35 PM - 12:55 PM    - The End of KRAS cancers?
Frank McCormick, PhD, FRS.  UCSF 

ADVANCES IN DIAGNOSTICS AND THERAPEUTICS
Session ADT04 - Challenges and Opportunities in the Development of Next Generation Antibody Drug Conjugates
April 28, 2025, 12:30 PM - 2:00 PM     Location to be announced
1:25 PM - 1:45 PM    - Managing and predicting toxicities from new and emerging ADCs
Hope S. Rugo. UCSF 

MAJOR SYMPOSIUM     Science and Health Policy, Regulatory Science and Policy
DC07 - Molecular Tumor Profiling for Pediatric Oncology
April 28, 2025, 3:00 PM - 4:30 PM     Room S106 - McCormick Place South (Level 1)
3:00 PM - 4:30 PM    - Chairperson
Alejandro Sweet-Cordero, MD UCSF

Tuesday, APRIL 29th

PLENARY    Tumor Microenvironment, Molecular/Cellular Bio
Session PL04 - Targeting the Cancer Ecosystem
April 29, 2025, 8:00 AM - 10:00 AM     Hall B1 - McCormick PlNorth (Level 3)
8:32 AM - 8:59 AM    - Leveraging tumor immune archetypes in treating cancer
Max Krummel, PhD. UCSF

CLINICAL TRIALS PLENARY SESSION
CTPL04 - Biologics and T-cell Engagers
April 29, 2025, 10:15 AM - 12:15 PM     Arie Crown Theater - McCormick Lakeside (Level 2)
11:00 AM - 11:10 AM    - Discussant
Hope S. Rugo. UCSF 

MAJOR SYMPOSIUM        Survivorship, Drug Dev, Clinical Research
Session SY05 - Cardio-Oncology: A Novel Platform for Investigation
April 29, 2025, 10:15 AM - 11:45 AM     Location to be announced
10:15 AM - 10:16 AM    - Chairperson & Presentation
10:20 AM - 10:40 AM    - Immune checkpoint inhibitors and cardiac toxicity: From mice to humans
Javid J. Moslehi, MD UCSF 

MAJOR SYMPOSIUM        Immunology
Session SY16 - Novel Classes of Human Cancer Rejection Antigens: Beyond Point Mutations
April 29, 2025, 10:15 AM - 11:45 AM     McCormick Lakeside Center (Level 3)
10:45 AM - 11:05 AM    - Tumor-wide RNA splicing aberrations generate therapeutically actionable public neoantigens
Hideho Okada, MD, PhD.  UCSF  

MINISYMPOSIUM - Novel Cancer Therapeutic Targets
April 29, 2025, 2:30 PM - 4:00 PM     Room S102 - McCormick Place South (Level 1)
2:50 PM - 3:05 PM    Unveiling the potent anti-tumor activity and underlying mechanism of action of the novel pan-RAF inhibitor exarafenib in BRAF-mutated NSCLC
Tadashi Manabe, MD, PhD.  UCSF

Wednesday, APRIL 30th

MAJOR SYMPOSIUM Experimental and Molecular Therapeutics,Drug Development
April 30, 2025, 10:15 AM - 11:45 AM     Location to be announced
Session SY29 - Biomolecular Condensates in Cancer: Mechanisms and Therapeutic Opportunities
10:45 AM - 11:05 AM    - New physical biology of oncoprotein condensates: Differential regulation of the transcriptome by phase separation
Xiaokun Shu, PhD. UCSF 

PLENARY SESSION
Session PL06 - AACR Annual Meeting 2025 Highlights: Vision for the Future
April 30, 2025, 12:10 PM - 1:30 PM     Arie Crown Theater - McCormick Lakeside Center (Level 2)
12:39 PM - 1:04 PM    - Prevention, early detection, population sciences, and disparities research
Scarlett L. Gomez, PhD, MPH. UCSF