Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer. Read more about Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer.
Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A. Read more about Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A.
Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3. Read more about Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3.
Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Read more about Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers.
Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding. Read more about Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding.
Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex. Read more about Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine. Read more about Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine.
A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography. Read more about A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography.
End-Binding E3 Ubiquitin Ligases Enable Protease Signaling. Read more about End-Binding E3 Ubiquitin Ligases Enable Protease Signaling.
A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein-Protein Interactions. Read more about A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein-Protein Interactions.