Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference. Read more about Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference.
Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of Two Intracellular Proteins. Read more about Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of Two Intracellular Proteins.
Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer. Read more about Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer.
Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance. Read more about Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.
Mass spectrometry-based detection and assignment of protein posttranslational modifications. Read more about Mass spectrometry-based detection and assignment of protein posttranslational modifications.
Structure of the human autophagy initiating kinase ULK1 in complex with potent inhibitors. Read more about Structure of the human autophagy initiating kinase ULK1 in complex with potent inhibitors.
Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification. Read more about Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification.
Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors. Read more about Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors.
Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness. Read more about Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness.
Antibacterial activity of and resistance to small molecule inhibitors of the ClpP peptidase. Read more about Antibacterial activity of and resistance to small molecule inhibitors of the ClpP peptidase.
