Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology. Read more about Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology.
Inhibitors of difficult protein-protein interactions identified by high-throughput screening of multiprotein complexes. Read more about Inhibitors of difficult protein-protein interactions identified by high-throughput screening of multiprotein complexes.
A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels. Read more about A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels.
Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models. Read more about Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models.
Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation. Read more about Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation.
Fine-tuning multiprotein complexes using small molecules. Read more about Fine-tuning multiprotein complexes using small molecules.
Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation. Read more about Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.
Release factor one is nonessential in Escherichia coli. Read more about Release factor one is nonessential in Escherichia coli.
The three cornerstones of chemical biology: innovative probes, new discoveries, and enabling tools. Read more about The three cornerstones of chemical biology: innovative probes, new discoveries, and enabling tools.
Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs. Read more about Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs.