Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells. Read more about Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells.
Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors. Read more about Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors.
Synthesis and evaluation of inhibitors of bacterial drug efflux pumps of the major facilitator superfamily. Read more about Synthesis and evaluation of inhibitors of bacterial drug efflux pumps of the major facilitator superfamily.
Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes. Read more about Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes.
Diversity-oriented synthesis of cyclic acyldepsipeptides leads to the discovery of a potent antibacterial agent. Read more about Diversity-oriented synthesis of cyclic acyldepsipeptides leads to the discovery of a potent antibacterial agent.
Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesis. Read more about Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesis.
Development of an optimized activatable MMP-14 targeted SPECT imaging probe. Read more about Development of an optimized activatable MMP-14 targeted SPECT imaging probe.
Using specificity to strategically target proteases. Read more about Using specificity to strategically target proteases.
Recent developments in the identification of novel oxazolidinone antibacterial agents. Read more about Recent developments in the identification of novel oxazolidinone antibacterial agents.
Targeting the gatekeeper residue in phosphoinositide 3-kinases. Read more about Targeting the gatekeeper residue in phosphoinositide 3-kinases.
