Mitochondrial Protein Carboxyl-Terminal Alanine-Threonine Tailing Promotes Human Glioblastoma Growth by Regulating Mitochondrial Function. Read more about Mitochondrial Protein Carboxyl-Terminal Alanine-Threonine Tailing Promotes Human Glioblastoma Growth by Regulating Mitochondrial Function.
Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens. Read more about Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens.
Cathepsin C-Catalyzed Ligation Generates Intralysosomal Amyloid Fibrils from Dipeptide Esters. Read more about Cathepsin C-Catalyzed Ligation Generates Intralysosomal Amyloid Fibrils from Dipeptide Esters.
Crystallographic Ensembles Reveal the Structural Basis of Binding Entropy in SARS-CoV2 Macrodomain. Read more about Crystallographic Ensembles Reveal the Structural Basis of Binding Entropy in SARS-CoV2 Macrodomain.
Functional diversification of the cephalopod proteome by RNA-editing. Read more about Functional diversification of the cephalopod proteome by RNA-editing.
Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells. Read more about Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells.
Disruption of Cell-Type-Specific Molecular Programs of Medium Spiny Neurons in Autism. Read more about Disruption of Cell-Type-Specific Molecular Programs of Medium Spiny Neurons in Autism.
A spatial transcriptomic atlas of autism-associated genes identifies convergence in the developing human thalamus. Read more about A spatial transcriptomic atlas of autism-associated genes identifies convergence in the developing human thalamus.
Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy in vivo. Read more about Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy in vivo.
Macrodomain ADP-ribose binding but not ADP-ribosylhydrolase activity is critical for chikungunya virus infection of Aedes mosquitoes. Read more about Macrodomain ADP-ribose binding but not ADP-ribosylhydrolase activity is critical for chikungunya virus infection of Aedes mosquitoes.
