The disease-causing tau V337M mutation induces tau hypophosphorylation and perturbs axon morphology pathways. Read more about The disease-causing tau V337M mutation induces tau hypophosphorylation and perturbs axon morphology pathways.
D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response. Read more about D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response.
A prostate cancer gastrointestinal transcriptional phenotype may be associated with diminished response to AR-targeted therapy. Read more about A prostate cancer gastrointestinal transcriptional phenotype may be associated with diminished response to AR-targeted therapy.
Predicted mechanistic impacts of human protein missense variants. Read more about Predicted mechanistic impacts of human protein missense variants.
Loss of neutrophil Shp1 produces hemorrhagic and lethal acute lung injury. Read more about Loss of neutrophil Shp1 produces hemorrhagic and lethal acute lung injury.
Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines. Read more about Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines.
Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation. Read more about Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation.
Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids. Read more about Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids.
Lack of TGFβ signaling competency predicts immune poor cancer conversion to immune rich and response to checkpoint blockade. Read more about Lack of TGFβ signaling competency predicts immune poor cancer conversion to immune rich and response to checkpoint blockade.
