A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities. Read more about A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities.
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine. Read more about Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine.
Identifying and antagonizing the interactions between layilin and glycosylated collagens. Read more about Identifying and antagonizing the interactions between layilin and glycosylated collagens.
Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer. Read more about Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer.
How do you mend inactive tumor suppressor mutants? You glue them! Read more about How do you mend inactive tumor suppressor mutants? You glue them!
Reimagining dots and dashes: Visualizing structure and function of organelles for high-content imaging analysis. Read more about Reimagining dots and dashes: Visualizing structure and function of organelles for high-content imaging analysis.
Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Read more about Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering.
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone. Read more about Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound. Read more about Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound.
