Shear stress control of vascular leaks and atheromas through Tie2 activation by VE-PTP sequestration. Read more about Shear stress control of vascular leaks and atheromas through Tie2 activation by VE-PTP sequestration.
Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression. Read more about Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression.
MicroRNA-574 regulates FAM210A expression and influences pathological cardiac remodeling. Read more about MicroRNA-574 regulates FAM210A expression and influences pathological cardiac remodeling.
PARP-1 regulates DNA repair factor availability. Read more about PARP-1 regulates DNA repair factor availability.
Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. Read more about Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.
Consequence of the tumor-associated conversion to cyclin D1b. Read more about Consequence of the tumor-associated conversion to cyclin D1b.
Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells. Read more about Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells.
Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition. Read more about Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition.
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors. Read more about Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.
Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2. Read more about Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2.