Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics. Read more about Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics.
A Genetically Encoded Fluorosulfonyloxybenzoyl-l-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry. Read more about A Genetically Encoded Fluorosulfonyloxybenzoyl-l-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry.
Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1. Read more about Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1.
Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates. Read more about Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates.
Reactivity-Based Probe of the Iron(II)-Dependent Interactome Identifies New Cellular Modulators of Ferroptosis. Read more about Reactivity-Based Probe of the Iron(II)-Dependent Interactome Identifies New Cellular Modulators of Ferroptosis.
Targeting Phosphotyrosine in Native Proteins with Conditional, Bispecific Antibody Traps. Read more about Targeting Phosphotyrosine in Native Proteins with Conditional, Bispecific Antibody Traps.
Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents. Read more about Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents.
Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction. Read more about Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction.
Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking. Read more about Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking.
Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90. Read more about Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90.