Electrophilic fragment-based design of reversible covalent kinase inhibitors. Read more about Electrophilic fragment-based design of reversible covalent kinase inhibitors.
Ordering a dynamic protein via a small-molecule stabilizer. Read more about Ordering a dynamic protein via a small-molecule stabilizer.
Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding. Read more about Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding.
Selective targeting of distinct active site nucleophiles by irreversible SRC-family kinase inhibitors. Read more about Selective targeting of distinct active site nucleophiles by irreversible SRC-family kinase inhibitors.
Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. Read more about Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis.
A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase. Read more about A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase.
Proximal ligand electron donation and reactivity of the cytochrome P450 ferric-peroxo anion. Read more about Proximal ligand electron donation and reactivity of the cytochrome P450 ferric-peroxo anion.
Inverse-phosphocholine lipids: a remix of a common phospholipid. Read more about Inverse-phosphocholine lipids: a remix of a common phospholipid.
Chemically programmed cell adhesion with membrane-anchored oligonucleotides. Read more about Chemically programmed cell adhesion with membrane-anchored oligonucleotides.
Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation. Read more about Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation.
