Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis. Read more about Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis.
Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification. Read more about Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.
A modular approach for assembling aldehyde-tagged proteins on DNA scaffolds. Read more about A modular approach for assembling aldehyde-tagged proteins on DNA scaffolds.
Restriction of the conformational dynamics of the cyclic acyldepsipeptide antibiotics improves their antibacterial activity. Read more about Restriction of the conformational dynamics of the cyclic acyldepsipeptide antibiotics improves their antibacterial activity.
Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology. Read more about Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology.
An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells. Read more about An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells.
Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways. Read more about Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways.
Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site. Read more about Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site.
Electrophilic fragment-based design of reversible covalent kinase inhibitors. Read more about Electrophilic fragment-based design of reversible covalent kinase inhibitors.
Ordering a dynamic protein via a small-molecule stabilizer. Read more about Ordering a dynamic protein via a small-molecule stabilizer.
