Substrate binding drives large-scale conformational changes in the Hsp90 molecular chaperone. Read more about Substrate binding drives large-scale conformational changes in the Hsp90 molecular chaperone.
Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Read more about Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly.
Membranes in balance: mechanisms of sphingolipid homeostasis. Read more about Membranes in balance: mechanisms of sphingolipid homeostasis.
Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin. Read more about Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Read more about Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha.
Repair scaffolding reaches new heights at blocked replication forks. Read more about Repair scaffolding reaches new heights at blocked replication forks.
The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion. Read more about The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion.
HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. Read more about HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.
A drug-drug interaction crystallizes a new entry point into the UPR. Read more about A drug-drug interaction crystallizes a new entry point into the UPR.
Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation. Read more about Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation.
