Direct, noncatalytic mechanism of IKK inhibition by A20. Read more about Direct, noncatalytic mechanism of IKK inhibition by A20.
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Read more about SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP. Read more about Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP.
The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2. Read more about The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2.
Client-loading conformation of the Hsp90 molecular chaperone revealed in the cryo-EM structure of the human Hsp90:Hop complex. Read more about Client-loading conformation of the Hsp90 molecular chaperone revealed in the cryo-EM structure of the human Hsp90:Hop complex.
Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation. Read more about Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation.
Dynamics of Cdk1 substrate specificity during the cell cycle. Read more about Dynamics of Cdk1 substrate specificity during the cell cycle.
Cdk1-dependent destruction of Eco1 prevents cohesion establishment after S phase. Read more about Cdk1-dependent destruction of Eco1 prevents cohesion establishment after S phase.
Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Read more about Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms. Read more about Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms.