Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. Read more about Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer.
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice. Read more about Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination. Read more about Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination.
Learned adaptive multiphoton illumination microscopy for large-scale immune response imaging. Read more about Learned adaptive multiphoton illumination microscopy for large-scale immune response imaging.
The transcriptional landscape of Shh medulloblastoma. Read more about The transcriptional landscape of Shh medulloblastoma.
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer. Read more about CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer.
Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions. Read more about Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions.
Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia. Read more about Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia.
Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling. Read more about Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling.
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. Read more about Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.