Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling. Read more about Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling.
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome. Read more about Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.
KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Read more about KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. Read more about A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.
Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. Read more about Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts.
Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions. Read more about Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions.
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair. Read more about The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair.
Non-invasive assessment of telomere maintenance mechanisms in brain tumors. Read more about Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma. Read more about PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma.
Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction. Read more about Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction.
