Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential. Read more about Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential.
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Read more about TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Microbial production of megadalton titin yields fibers with advantageous mechanical properties. Read more about Microbial production of megadalton titin yields fibers with advantageous mechanical properties.
Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS. Read more about Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS.
Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization. Read more about Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization.
Author Correction: PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma. Read more about Author Correction: PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma.
An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer. Read more about An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer.
Brain-specific inhibition of mTORC1 eliminates side effects resulting from mTORC1 blockade in the periphery and reduces alcohol intake in mice. Read more about Brain-specific inhibition of mTORC1 eliminates side effects resulting from mTORC1 blockade in the periphery and reduces alcohol intake in mice.
BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons. Read more about BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons.
Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells. Read more about Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells.
