Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Read more about Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer.
Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors. Read more about Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors.
Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers. Read more about Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Read more about Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Read more about Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer. Read more about RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.
A B cell-dependent mechanism restrains T cell transendothelial migration. Read more about A B cell-dependent mechanism restrains T cell transendothelial migration.
Targeting the MLL complex in castration-resistant prostate cancer. Read more about Targeting the MLL complex in castration-resistant prostate cancer.
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Read more about The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma. Read more about Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
