Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma. Read more about Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma.
Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition. Read more about Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
High mobility group box 1 promotes tumor cell migration through epigenetic silencing of semaphorin 3A. Read more about High mobility group box 1 promotes tumor cell migration through epigenetic silencing of semaphorin 3A.
Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations. Read more about Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.
Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells. Read more about Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells.
Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development. Read more about Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development.
Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer. Read more about Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer.
Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors. Read more about Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors.
Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin. Read more about Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin.
Targeting Gli transcription activation by small molecule suppresses tumor growth. Read more about Targeting Gli transcription activation by small molecule suppresses tumor growth.