Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica. Read more about Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica.
Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51. Read more about Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51.
Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni. Read more about Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni.
A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit. Read more about A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit.
Mining a cathepsin inhibitor library for new antiparasitic drug leads. Read more about Mining a cathepsin inhibitor library for new antiparasitic drug leads.
Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system. Read more about Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system.
Biochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4. Read more about Biochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4.
Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. Read more about Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening.
SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni. Read more about SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni.
