Protein-coding changes preceded cis-regulatory gains in a newly evolved transcription circuit. Read more about Protein-coding changes preceded cis-regulatory gains in a newly evolved transcription circuit.
p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. Read more about p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Depletion of microbiome-derived molecules in the host using Clostridium genetics. Read more about Depletion of microbiome-derived molecules in the host using Clostridium genetics.
Massively multiplex chemical transcriptomics at single-cell resolution. Read more about Massively multiplex chemical transcriptomics at single-cell resolution.
Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Read more about Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome.
Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases. Read more about Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Read more about Exploring genetic interaction manifolds constructed from rich single-cell phenotypes.
Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism. Read more about Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism.