Piquing our interest: Insights into the role of PEAK3 in signaling and disease. Read more about Piquing our interest: Insights into the role of PEAK3 in signaling and disease.
Dissecting the biology of mTORC1 beyond rapamycin. Read more about Dissecting the biology of mTORC1 beyond rapamycin.
Control of ribosomal protein synthesis by the Microprocessor complex. Read more about Control of ribosomal protein synthesis by the Microprocessor complex.
A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands. Read more about A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands.
Redox priming promotes Aurora A activation during mitosis. Read more about Redox priming promotes Aurora A activation during mitosis.
Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. Read more about Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability.
CD45 functions as a signaling gatekeeper in T cells. Read more about CD45 functions as a signaling gatekeeper in T cells.
CARD9 mediates dendritic cell-induced development of Lyn deficiency-associated autoimmune and inflammatory diseases. Read more about CARD9 mediates dendritic cell-induced development of Lyn deficiency-associated autoimmune and inflammatory diseases.
Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation. Read more about Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation.
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies. Read more about KRASG12C inhibition produces a driver-limited state revealing collateral dependencies.