Research Summary

The body of research I developed during my graduate and postdoctoral training focused on characterizing & augmenting aspects of cognitive control & skill acquisition using behavioral and neuroimaging technologies. Creating a unique line of research that built upon these domains has involved a strong interdisciplinary emphasis, with these efforts centered on healthy young and older adults, as well as clinical populations involving ADHD, autism, and depressed individuals amongst others. My current work leverages state-of-the-art technological approaches to create i) advanced training tools to remediate cognitive deficiencies (see our cover story in Nature, Anguera et al., 2013) and ii) use mobile technology to robustly characterizing individual abilities in each of these domains outside of the laboratory (contributed to the creation of 10 different mobile apps to date; see Anguera et al., 2016 as an example).

Research Funding

  • September 5, 2021 - May 31, 2023 - Building a shared infrastructure for cognitive assessment in the service of cognitive training research , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21AG074497
  • February 1, 2019 - November 30, 2021 - Enhancing cognitive control abilities using mobile technology in a senior living community , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21AG058896
  • September 19, 2016 - August 31, 2021 - A Computerized Intervention Targeting Cognitive Control Network Deficits in Depression , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R33MH110509
  • August 11, 2017 - July 31, 2021 - Multi-modal Study of Cognitive and Neural Differences in Media Multitaskers , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R56MH111672


  • University of California San Diego, BS, 2000, Physiology/Neuroscience
  • California State University Northridge, MS, 2004, Kinesiology
  • University of Michigan Ann Arbor, PhD, 2008, Kinesiology
  • University of California San Francisco, 2013, Neurology (Postdoctoral Fellow)
  • University of California San Francisco, 2014, Psychiatry (Research Scientist)

Honors & Awards


  • 2006-2008
    Minority Predoctoral Supplement for Underrepresented Minorities
  • 2007
    University of Michigan Rackham Graduate Student Dissertation Research Grant 
  • 2009-2010
    Minority Postdoctoral Supplement for Underrepresented Minorities
  • 2010-2013
    UCSF Institutional Research and Career Development Award
  • 2011-2014
    NIH Loan Repayment Program recipient
  • 2013
    Ambassador for UCSF 2.0 ‘An Experiment to Identify Bold Ideas for the Future’
  • 2014
    UCSF 150th Anniversary “Young Innovator Awardee” 
  • 2014
    UCSF School of Medicine Technology Transformation Grant
  • 2014
    UCSF Center for Aging in Diverse Communities (CADC) Grant

Selected Publications

  1. Ziegler DA, Anguera JA, Gallen CL, Hsu WY, Wais PE, Gazzaley A. Leveraging technology to personalize cognitive enhancement methods in aging. Nat Aging. 2022 Jun; 2(6):475-483.  View on PubMed
  2. Li G, McGill M, Brewster S, Chen CP, Anguera JA, Gazzaley A, Pollick F. Multimodal Biosensing for Vestibular Network-Based Cybersickness Detection. IEEE J Biomed Health Inform. 2022 06; 26(6):2469-2480.  View on PubMed
  3. Gallen CL, Anguera JA, Gerdes MR, Simon AJ, Cañadas E, Marco EJ. Enhancing neural markers of attention in children with ADHD using a digital therapeutic. PLoS One. 2021; 16(12):e0261981.  View on PubMed
  4. Hsu WY, Rowles W, Anguera JA, Anderson A, Younger JW, Friedman S, Gazzaley A, Bove R. Assessing Cognitive Function in Multiple Sclerosis With Digital Tools: Observational Study. J Med Internet Res. 2021 12 30; 23(12):e25748.  View on PubMed
  5. Oppegaard K, Harris CS, Shin J, Paul SM, Cooper BA, Chan A, Anguera JA, Levine J, Conley Y, Hammer M, Miaskowski CA, Chan RJ, Kober KM. Cancer-related cognitive impairment is associated with perturbations in inflammatory pathways. Cytokine. 2021 12; 148:155653.  View on PubMed
  6. Coulanges L, Abreu-Mendoza RA, Varma S, Uncapher MR, Gazzaley A, Anguera J, Rosenberg-Lee M. Linking inhibitory control to math achievement via comparison of conflicting decimal numbers. Cognition. 2021 09; 214:104767.  View on PubMed
  7. Gunning FM, Anguera JA, Victoria LW, Areán PA. A digital intervention targeting cognitive control network dysfunction in middle age and older adults with major depression. Transl Psychiatry. 2021 05 04; 11(1):269.  View on PubMed
  8. Anguera JA, Schachtner JN, Simon AJ, Volponi J, Javed S, Gallen CL, Gazzaley A. Long-term maintenance of multitasking abilities following video game training in older adults. Neurobiol Aging. 2021 07; 103:22-30.  View on PubMed
  9. Jurigova BG, Gerdes MR, Anguera JA, Marco EJ. Sustained benefits of cognitive training in children with inattention, three-year follow-up. PLoS One. 2021; 16(2):e0246449.  View on PubMed
  10. Wang T, Merkle EC, Anguera JA, Turner BM. Score-based tests for detecting heterogeneity in linear mixed models. Behav Res Methods. 2021 02; 53(1):216-231.  View on PubMed
  11. Hsu WY, Rowles W, Anguera JA, Zhao C, Anderson A, Alexander A, Sacco S, Henry R, Gazzaley A, Bove R. Correction: Application of an Adaptive, Digital, Game-Based Approach for Cognitive Assessment in Multiple Sclerosis: Observational Study. J Med Internet Res. 2021 Jan 27; 23(1):e27440.  View on PubMed
  12. Hsu WY, Rowles W, Anguera JA, Zhao C, Anderson A, Alexander A, Sacco S, Henry R, Gazzaley A, Bove R. Application of an Adaptive, Digital, Game-Based Approach for Cognitive Assessment in Multiple Sclerosis: Observational Study. J Med Internet Res. 2021 01 20; 23(1):e24356.  View on PubMed
  13. Atallah M, Cooper B, Muñoz RF, Paul SM, Anguera J, Levine JD, Hammer M, Wright F, Chen LM, Melisko M, Conley YP, Miaskowski C, Dunn LB. Psychological Symptoms and Stress Are Associated With Decrements in Attentional Function in Cancer Patients Undergoing Chemotherapy. Cancer Nurs. 2020 Sep/Oct; 43(5):402-410.  View on PubMed
  14. Bove R, Rowles W, Zhao C, Anderson A, Friedman S, Langdon D, Alexander A, Sacco S, Henry R, Gazzaley A, Feinstein A, Anguera JA. A novel in-home digital treatment to improve processing speed in people with multiple sclerosis: A pilot study. Mult Scler. 2021 04; 27(5):778-789.  View on PubMed
  15. Li G, Anguera JA, Javed SV, Khan MA, Wang G, Gazzaley A. Enhanced Attention Using Head-mounted Virtual Reality. J Cogn Neurosci. 2020 08; 32(8):1438-1454.  View on PubMed
  16. Allison R. Kaup, Jessica Schachtner, Amy L. Byers, Deborah E. Barnes, Joaquin A. Anguera, Alexandrea L. Harmell, Maria-Paulina Amaya, Margaret Gross, Kristine Yaffe. MOBILE COGNITIVE INTERVENTION IN OLDER VETERANS WITH TRAUMATIC BRAIN INJURY: RESULTS FROM THE BRAVE (BRAIN AGING IN VETERANS) TRAINING PILOT STUDY. Alzheimer's & Dementia. 2019 Jul 1; 15(7):p253-p254.  View on PubMed
  17. Ziegler DA, Simon AJ, Gallen CL, Skinner S, Janowich JR, Volponi JJ, Rolle CE, Mishra J, Kornfield J, Anguera JA, Gazzaley A. Closed-loop digital meditation improves sustained attention in young adults. Nat Hum Behav. 2019 07; 3(7):746-757.  View on PubMed
  18. Christian Thompson, Brigid Larkin, Josh Volponi, Alexander Simon, Joaquin Anguera, Adam Gazzaley. Maximal Oxygen Uptake Responders Versus Non-responders Show Differing Cognitive Responses to Movement-based Video Game Training. Medicine & Science in Sports & Exercise. 2019 Jun 1; 51(Supplement):850.  View on PubMed
  19. Brandes-Aitken A, Anguera JA, Chang YS, Demopoulos C, Owen JP, Gazzaley A, Mukherjee P, Marco EJ. White Matter Microstructure Associations of Cognitive and Visuomotor Control in Children: A Sensory Processing Perspective. Front Integr Neurosci. 2018; 12:65.  View on PubMed
  20. Bove RM, Rush G, Zhao C, Rowles W, Garcha P, Morrissey J, Schembri A, Alailima T, Langdon D, Possin K, Gazzaley A, Feinstein A, Anguera J. A Videogame-Based Digital Therapeutic to Improve Processing Speed in People with Multiple Sclerosis: A Feasibility Study. Neurol Ther. 2019 Jun; 8(1):135-145.  View on PubMed

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