Research Summary

I am an advanced heart failure and heart transplant cardiologist who has expertise in the management of patients with heart failure and pulmonary hypertension, heart transplant, and mechanical circulatory support devices. I am co-Director of the UCSF Comprehensive Amyloidosis Program, and the clinical cardiology lead for the UCSF HHT Center of Excellence. In addition to my expertise in heart failure and cardiomyopathies, I developed a specific focus in cardio-oncology (management of cardiovascular issues in cancer patients).

My research interests focus on understanding infiltrative and inflammatory heart diseases.

Education

2020 - Diversity, Equity, and Inclusion Champion Training, University of California
Fellowship, 2018 - Advanced Heart Failure/Transplant, University of California
Fellowship, 2017 - Cardiovascular disease, University of California
Residency, 2014 - Internal Medicine, Duke University Medical Center
MD, PhD, 2011 - Medicine, Neurobiology, University of Pittsburgh

Honors & Awards

  • ACC Clinical Excellence in Cardiology Fellowship Award, UCSF, 2016
  • Califf Medicine Resident Research Award, Duke, 2014
  • International Society for Zinc Biology Best Poster Award, 2009
  • International Society for Zinc Biology Best Student Oral Presentation, 2008
  • Summa Cum Laude with Honors, University of Pittsburgh, 2004

Selected Publications

  1. Gertz MA, Aras MA, Bart N, Brannagan TH, Griffin JM, Kontorovich AR, Rosen AM Unravelling the myriad physiologic roles of transthyretin: critical considerations for treating transthyretin amyloidosis.  View on PubMed
  2. Qin J, Aras MA, Song EJ, Connolly AJ, Zhou L, O'Brien C, Salem JE, Padmanabhan A, Moslehi JJ Insights Into Recovery From Acute Fulminant Myocarditis Following Successful Treatment With Ruxolitinib by Comprehensive Single-Cell Profiling.  View on PubMed
  3. Masri A, Aras M, Grogan M, Jacoby D, Maurer MS, Shah SJ, Witteles R, Wong PW, Ji AX, DU J, Siddhanti S, Katz L, Sinha U, Fox JC, Judge DP. Acoramidis for Transthyretin Amyloid Cardiomyopathy: Open-Label Extension Study Long-Term Follow-Up. J Card Fail. 2025 Apr 09.  View on PubMed
  4. Chen YC, Dolladille C, Rao A, Palaskas NL, Deswal A, Lehmann L, Cautela J, Courand PY, Hayek S, Zhu H, Cheng RK, Alexandre J, Baldassarre LA, Roubille F, Laufer-Perl M, Asnani A, Ederhy S, Tamura Y, Francis S, Gaughan EM, Johnson DB, Flint DL, Rainer PP, Bailly G, Ewer SM, Aras MA, Arangalage D, Cariou E, Florido R, Peretto G, Itzhaki Ben Zadok O, Akhter N, Narezkina A, Levenson JE, Liu Y, Crusz SM, Issa N, Piriou N, Leong D, Sandhu S, Turker I, Moliner P, Obeid M, Heinzerling L, Chang WT, Stewart A, Venkatesh V, Du Z, Yadavalli A, Kim D, Chandra A, Zhang KW, Power JR, Moslehi J, Salem JE, Zaha VG, International ICI Myocarditis Registry. Immune Checkpoint Inhibitor Myocarditis and Left Ventricular Systolic Dysfunction. JACC CardioOncol. 2025 Apr; 7(3):234-248.  View on PubMed
  5. Tsai KK, Chang AY, Abouzeid CM, Aras MA, Fang Q, Bibby D, Haghighat L, Hilton JF, Daud AI, Schiller NB. Longitudinal Evaluation of Immune Checkpoint Inhibitor-Induced Fatigue Syndrome by Rest, Stress, and Speckle-Tracking Strain Echocardiography. Echocardiography. 2025 Apr; 42(4):e70158.  View on PubMed
  6. Yurk D, Barrios JP, Labrecque Langlais E, Avram R, Aras MA, Abu-Mostafa Y, Padmanabhan A, Tison GH. Automated Assessment of Right Atrial Pressure From Ultrasound Videos Using Machine Learning. JACC Adv. 2024 Sep; 3(9):101192.  View on PubMed
  7. Lassen MCH, Arya F, Biering-Sørensen T, Reeh JLT, Melisko ME, Sarwary S, Baik AH, Aras MA, Qasim A. Left atrial strain is reduced following trastuzumab in breast cancer patients. Echocardiography. 2024 Jan; 41(1):e15751.  View on PubMed
  8. Ahmad Masri, Mandar Aras, Rodney H. Falk, Martha Grogan, Daniel Jacoby, Mathew S. Maurer, Sanjiv J. Shah, Ronald Witteles, Paul W. Wong, Alan X. Ji, Jing Du, Suresh Siddhanti, Uma Sinha, Jonathan C. Fox, Daniel P. Judge. Long-term Safety And Tolerability Of Acoramidis (AG10) In Symptomatic Transthyretin Amyloid Cardiomyopathy: 4-year Update From An Ongoing, Phase 2, Open-label Extension Study. Journal of Cardiac Failure. 2024 Jan 1; 30(1):221.  View on PubMed
  9. Stern LK, Grodin JL, Maurer MS, Ruberg FL, Patel AR, Khouri MG, Roth LR, Aras MA, Bhardwaj A, Bhattacharya P, Brailovsky Y, Drachman BM, Ebong IA, Fine NM, Gaggin H, Gopal D, Griffin J, Judge D, Kim P, Mitchell J, Mitter SS, Mohan RC, Ramos H, Reyentovich A, Sheikh FH, Sperry B, Carter S, Urey M, Vaishnav J, Vest AR, Kittleson MM, Patel JK. The Cardiac Amyloidosis Registry Study (CARS): Rationale, Design and Methodology. J Card Fail. 2024 May; 30(5):669-678.  View on PubMed
  10. Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Chenna A, Yee B, Winslow J, Petropoulos C, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV. J Am Heart Assoc. 2023 10 17; 12(20):e030896.  View on PubMed
  11. Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, Martin JN, Lee YJ, Aras MA, Long CS, Grandis DJ, Deeks SG, Hsue PY. Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019. J Infect Dis. 2023 08 31; 228(5):542-554.  View on PubMed
  12. Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID with Exercise Capacity and Chronotropic Incompetence among People with HIV. medRxiv. 2023 May 02.  View on PubMed
  13. Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, Martin JN, Lee YJ, Aras MA, Long CS, Grandis DJ, Deeks SG, Hsue PY. Reduced exercise capacity, chronotropic incompetence, and early systemic inflammation in cardiopulmonary phenotype Long COVID. medRxiv. 2023 Mar 21.  View on PubMed
  14. Kennedy VE, Natsuhara K, Maringanti SA, Shah ND, Arora S, Wolf J, Martin TG, Aras MA, Chung A, Wong SW. Daratumumab Plus Bortezomib and Dexamethasone in Newly Diagnosed Systemic Light Chain Amyloidosis. Curr Probl Cancer. 2023 06; 47(3):100953.  View on PubMed
  15. Aras MA, Abreau S, Mills H, Radhakrishnan L, Klein L, Mantri N, Rubin B, Barrios J, Chehoud C, Kogan E, Gitton X, Nnewihe A, Quinn D, Bridges C, Butte AJ, Olgin JE, Tison GH. Electrocardiogram Detection of Pulmonary Hypertension Using Deep Learning. J Card Fail. 2023 07; 29(7):1017-1028.  View on PubMed
  16. Lai M, Aras MA, Park M. Post-transplant ejection fraction and renal failure in cardiac transplant recipients: An analysis of the OPTN database. Clin Transplant. 2023 02; 37(2):e14881.  View on PubMed
  17. Benza RL, Franco V, Aras MA, Spikes L, Grinnan D, Satler C. Safety and efficacy of RT234 vardenafil inhalation powder on exercise parameters in pulmonary arterial hypertension: phase II, dose-escalation study design. Respir Res. 2022 Dec 17; 23(1):355.  View on PubMed
  18. Durstenfeld MS, Sun K, Tahir P, Peluso MJ, Deeks SG, Aras MA, Grandis DJ, Long CS, Beatty A, Hsue PY. Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic Review and Meta-analysis. JAMA Netw Open. 2022 10 03; 5(10):e2236057.  View on PubMed
  19. Nowatzke J, Guedeney P, Palaskas N, Lehmann L, Ederhy S, Zhu H, Cautela J, Francis S, Courand PY, Deswal A, Ewer SM, Aras M, Arangalage D, Ghafourian K, Fenioux C, Finke D, Peretto G, Zaha V, Itzhaki Ben Zadok O, Tajiri K, Akhter N, Levenson J, Baldassarre L, Power J, Huang S, Collet JP, Moslehi J, Salem JE, International ICI-myocarditis registry contributors. Coronary artery disease and revascularization associated with immune checkpoint blocker myocarditis: Report from an international registry. Eur J Cancer. 2022 12; 177:197-205.  View on PubMed
  20. Durstenfeld MS, Sun K, Tahir PM, Peluso MJ, Deeks SG, Aras MA, Grandis DJ, Long CS, Beatty A, Hsue PY. Cardiopulmonary exercise testing to evaluate post-acute sequelae of COVID-19 ("Long COVID"): a systematic review and meta-analysis. medRxiv. 2022 Jun 16.  View on PubMed

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