Research Summary

I am an advanced heart failure and heart transplant cardiologist who has expertise in the management of patients with heart failure and pulmonary hypertension, heart transplant, and left ventricular assist devices (LVAD). I developed a specific focus in cardio-oncology (management of cardiovascular issues in cancer patients) and in cardiac amyloidosis.

My research interests focus on cardiac amyloidosis and in understanding risk predictors and outcomes of cancer patients with heart disease.

Education

2020 - Diversity, Equity, and Inclusion Champion Training, University of California
Fellowship, 2018 - Advanced Heart Failure/Transplant, University of California
Fellowship, 2017 - Cardiovascular disease, University of California
Residency, 2014 - Internal Medicine, Duke University Medical Center
MD, PhD, 2011 - Medicine, Neurobiology, University of Pittsburgh

Honors & Awards

  • ACC Clinical Excellence in Cardiology Fellowship Award, UCSF, 2016
  • Califf Medicine Resident Research Award, Duke, 2014
  • International Society for Zinc Biology Best Poster Award, 2009
  • International Society for Zinc Biology Best Student Oral Presentation, 2008
  • Summa Cum Laude with Honors, University of Pittsburgh, 2004

Selected Publications

  1. Power JR, Alexandre J, Choudhary A, Ozbay B, Hayek SS, Asnani A, Tamura Y, Aras M, Cautela J, Thuny F, Gilstrap L, Arangalage D, Ewer S, Huang S, Deswal A, Palaskas NL, Finke D, Lehmann LH, Ederhy S, Moslehi J, Salem JE, International ICI-Myocarditis Registry. Association of early electrical changes with cardiovascular outcomes in immune checkpoint inhibitor myocarditis. Arch Cardiovasc Dis. 2022 Apr 27.  View on PubMed
  2. Banerjee R, Lo M, Klein L, Aras M, Logan AC. Anthracyclines in a patient with acute leukemia and severe cardiomyopathy requiring mechanical support: A case report. J Oncol Pharm Pract. 2022 Apr; 28(3):729-732.  View on PubMed
  3. Lehmann LH, Cautela J, Palaskas N, Baik AH, Meijers WC, Allenbach Y, Alexandre J, Rassaf T, Müller OJ, Aras M, Asnani AH, Deswal A, Laufer-Perl M, Thuny F, Kerneis M, Hayek SS, Ederhy S, Salem JE, Moslehi JJ. Clinical Strategy for the Diagnosis and Treatment of Immune Checkpoint Inhibitor-Associated Myocarditis: A Narrative Review. JAMA Cardiol. 2021 11 01; 6(11):1329-1337.  View on PubMed
  4. Power JR, Alexandre J, Choudhary A, Ozbay B, Hayek S, Asnani A, Tamura Y, Aras M, Cautela J, Thuny F, Gilstrap L, Arangalage D, Ewer S, Huang S, Deswal A, Palaskas NL, Finke D, Lehman L, Ederhy S, Moslehi J, Salem JE, International ICI-Myocarditis Registry†. Electrocardiographic Manifestations of Immune Checkpoint Inhibitor Myocarditis. Circulation. 2021 11 02; 144(18):1521-1523.  View on PubMed
  5. Olusola Orimoloye, John R. Power, Joseph Nowatzke, Andrew M. Hughes, Lorenz Lehmann, Jennifer Cautela, Mandar Aras, Alison Weppler, Anna Narezkina, Giovanni Peretto, Michal Pela, Shanthini M. Crusz, Aarti Asnani, Joe-Elie Salem, Anita Deswal, Nicolas Palaskas, Javid Moslehi. ECHOCARDIOGRAPHIC FEATURES OF IMMUNE CHECKPOINT INHIBITOR ASSOCIATED MYOCARDITIS AND THEIR ASSOCIATION WITH ADVERSE OUTCOMES. Journal of the American College of Cardiology. 2021 May 1; 77(18):3336.  View on PubMed
  6. Gabriela Spencer-Bonilla, Joyce N. Njoroge, Keon Pearson, Ronald M. Witteles, Mandar A. Aras, Kevin M. Alexander. Racial and Ethnic Disparities in Transthyretin Cardiac Amyloidosis. Current Cardiovascular Risk Reports. 2021 Apr 4; 15(6):8.  View on PubMed
  7. Baik AH, Tsai KK, Oh DY, Aras MA. Mechanisms and clinical manifestations of cardiovascular toxicities associated with immune checkpoint inhibitors. Clin Sci (Lond). 2021 03 12; 135(5):703-724.  View on PubMed
  8. John R Power, Joachim Alexandre, Arrush Choudhary, benay ozbay, Nicolas L Palaskas, Lorenz H Lehmann, Daniel Finke, Jennifer Cautela, Franck Thuny, Yuichi Tamura, Salim S Hayek, Tariq U Azam, Aarti Asnani, Tyler Mehegan, Mandar A Aras, Alan H Baik, Lauren Gilstrap, Michal Laufer-Perl, Dimitri Arangalage, Steven Ewer, Matthew Martini, Joseph Nowatzke, Olusola A Orimoloye, Douglas M Brinkley, Wouter C Meijers, Charlotte Fenioux, Stephane EDERHY, Javid J Moslehi, Joe-elie Salem. Abstract 14843: Electrocardiographic Manifestations of Immune Checkpoint Inhibitor Associated Myocarditis. Circulation. 2020 Nov 17; 142(Suppl_3).  View on PubMed
  9. Joseph Nowatzke, John R Power, Wouter C Meijers, Olusola Orimoloye, Charlotte Fenioux, Yuichi Tamura, Jennifer Cautela, Lorenz H Lehmann, Daniel Finke, Salim Hayek, Tariq U Azam, Aarti Asnani, Tyler Mehegan, Alison Weppler, Alan H Baik, Mandar A Aras, Anna Narezkina, Dimitri Arangalage, fanny rocher, Gerard Alexandre, Nicolas L Palaskas, Joe-elie Salem, Javid Moslehi. Abstract 15365: Natural History of Immune Checkpoint Inhibitor Associated Myocarditis With Preserved Ejection Fraction. Circulation. 2020 Nov 17; 142(Suppl_3).  View on PubMed
  10. J Power, W Meijers, C Fenioux, Y Tamura, A Asnani, J Alexandre, J Cautela, M Aras, L Lehmann, M Perl, A Narezkina, L Gilstrap, S Ederhy, J Moslehi, J Salem. Predictors of steroid-refractory immune checkpoint inhibitor associated myocarditis. European Heart Journal. 2020 Nov 1; 41(Supplement_2).  View on PubMed
  11. Aras MA, Power JR, Moslehi JJ. Inflammatory Biomarkers to Detect Immune Checkpoint Inhibitor-Associated Cardiotoxicity in Lung Cancer Patients: Ready for Prime Time? JACC CardioOncol. 2020 Sep; 2(3):503-505.  View on PubMed
  12. Hasan Shandhi MM, Aras M, Wynn S, Fan J, Heller JA, Etemadi M, Klein L, Inan OT. Cardiac Function Monitoring for Patients Undergoing Cancer Treatments Using Wearable Seismocardiography: A Proof-of-Concept Study. Annu Int Conf IEEE Eng Med Biol Soc. 2020 07; 2020:4075-4078.  View on PubMed
  13. Roman Zingarelli, Mandar A Aras, Dwight Bibby, Qizhi Fang, Adil Daud, Nelson B Schiller, Katy K. Tsai. Prospective investigation of immunotherapy-induced fatigue by rest and stress echocardiography. Journal of Clinical Oncology. 2020 May 20; 38(15_suppl):e24060-e24060.  View on PubMed
  14. Abraham TP, Aras MA. Echo-Strain to Check Up on Checkpoint Inhibitors. J Am Coll Cardiol. 2020 02 11; 75(5):479-481.  View on PubMed
  15. Stern LK, Selby VN, Kolaitis NA, Boin F, Aras M, Klein L, De Marco T. Heart-lung transplantation: A viable option for connective tissue diseases. Clin Transplant. 2020 02; 34(2):e13776.  View on PubMed
  16. DesJardin JT, Manicardi M, Svetlichnaya Y, Kolaitis NA, Papolos AI, Selby VN, Zier LS, Klein L, Aras MA, Yao FY, Roberts JP, De Marco T. Noninvasive estimation of pulmonary vascular resistance improves portopulmonary hypertension screening in liver transplant candidates. Clin Transplant. 2019 07; 33(7):e13585.  View on PubMed
  17. Aras MA, Psotka MA, De Marco T. Pulmonary Hypertension Due to Left Heart Disease: an Update. Curr Cardiol Rep. 2019 05 27; 21(7):62.  View on PubMed
  18. Mandar A Aras, Lauren Cuevas, Dwight Bibby, Qizhi Fang, Adil Daud, Nelson B Schiller, Katy K. Tsai. Prospective cardiac function monitoring in immunotherapy-treated patients. Journal of Clinical Oncology. 2019 May 20; 37(15_suppl):e14157-e14157.  View on PubMed
  19. S. Bhattacharya, N. Colaco, M. Coleman, S. Sharma, M. Kassemos, M. Aras, V. Selby, T. De Marco, L. Klein, G. Wieselthaler. Gore-Tex Mesh as Cause for Distal Outflow Graft Obstruction in Ventricular Assist Device Patients. The Journal of Heart and Lung Transplantation. 2019 Apr 1; 38(4):s355.  View on PubMed
  20. Zhang J, Gajjala S, Agrawal P, Tison GH, Hallock LA, Beussink-Nelson L, Lassen MH, Fan E, Aras MA, Jordan C, Fleischmann KE, Melisko M, Qasim A, Shah SJ, Bajcsy R, Deo RC. Fully Automated Echocardiogram Interpretation in Clinical Practice. Circulation. 2018 10 16; 138(16):1623-1635.  View on PubMed

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