Research Funding

  • September 1, 2022 - August 31, 2026 - Discovering Infection-mediated Pathways of Glioma Etiology and Prognosis by Leveraging Multiplex Serology and Immunogenomics , Principle Investigator . Sponsor: NATIONAL CANCER INSTITUTE, Sponsor Award ID: 1R01CA266676
  • February 1, 2018 - January 31, 2021 - HKLE-seq: an enrichment method for unbiased amplification and next-generation sequencing of all HERV-K and SVA (HKLE) insertion breakpoints genome-wide in human DNA samples , Principal Investigator . Sponsor: NIH/NIGMS, Sponsor Award ID: R15GM126562

Education

PhD, 2014 - Epidemiology, University of California, Berkeley

Honors & Awards

  • 2023
    UCSF Cataylst Award - Extracellular Vesicle Research
  • 2017
    Senior Scholar Teaching/Mentorship Award, University of Nevada
  • 2016
    Brain Tumor Epidemiology Consortium (BTEC) Young Investigator Award, Barcelona, Spain
  • 2016
    Cancer Center Impact Award, University of California, San Francisco
  • 2014
    NIH T32 Fellowship, University of California, San Francisco
  • 2012
    Graduate Student Research Award, University of California, Berkeley

Selected Publications

  1. Bian S, Guo X, Yang X, Wei Y, Yang Z, Cheng S, Yan J, Chen Y, Chen GB, Du X, Francis SS, Shu Y, Liu S. Genetic determinants of IgG antibody response to COVID-19 vaccination. Am J Hum Genet. 2024 Jan 04; 111(1):181-199.  View on PubMed
  2. Kachuri L, Guerra GA, Wendt GA, Hansen HM, Molinaro AM, Bracci P, McCoy L, Rice T, Wiencke JK, Eckel-Passow JE, Jenkins RB, Wrensch M, Francis SS. Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival. medRxiv. 2023 Oct 16.  View on PubMed
  3. Francis SS, Guerra G, Hansen HM, Wendt G, Kachuri L, Wiencke JK, Wrensch M. Inherited polymorphisms in the Human Leukocyte Antigen Region modify the association between varicella-zoster virus antibody reactivity and glioma prognosis. Neuro Oncol. 2023 10 03; 25(10):1910-1912.  View on PubMed
  4. Guerra G, McCoy L, Hansen HM, Rice T, Molinaro AM, Wiemels JL, Wiencke JK, Wrensch M, Francis SS. Antibodies to varicella-zoster virus and three other herpesviruses and survival in adults with glioma. Neuro Oncol. 2023 06 02; 25(6):1047-1057.  View on PubMed
  5. Johnson KJ, Bauchet L, Francis SS, Hainfellner JA, Kruchko C, Lau CC, Ostrom QT, Scheurer ME, Yuan Y. Pediatric brain tumors: Origins, epidemiology, and classification - The 2022 Brain Tumor Epidemiology Consortium meeting report. Clin Neuropathol. 2023 Mar-Apr; 42(2):74-80.  View on PubMed
  6. Caiazza F, Conroy PC, Ivry SL, York T, Lin J, Hernandez S, Hoffmann TJ, Francis SS, Park WG, Yip-Schneider MT, Schmidt CM, Brand R, Craik CS, Kirkwood K. Accurate Identification of Mucinous Pancreatic Cystic Lesions Using Small-Volume Analytes. J Surg Res. 2023 04; 284:322-331.  View on PubMed
  7. Bracci PM, Rice T, Hansen HM, Francis SS, Lee S, McCoy LS, Shrestha PP, Warrier G, Clarke JL, Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR. Pre-surgery immune profiles of adult glioma patients. J Neurooncol. 2022 Aug; 159(1):103-115.  View on PubMed
  8. Guerra G, Kachuri L, Wendt G, Hansen HM, Mack SJ, Molinaro AM, Rice T, Bracci P, Wiencke JK, Kasahara N, Eckel-Passow JE, Jenkins RB, Wrensch M, Francis SS. The immunogenetics of viral antigen response is associated with subtype-specific glioma risk and survival. Am J Hum Genet. 2022 06 02; 109(6):1105-1116.  View on PubMed
  9. Gallant RE, Arroyo K, Bracci PM, Li S, Metayer C, Kogan SC, Wendt GA, Francis SS, de Smith AJ, Wiemels JL. Clinical characteristics of cytomegalovirus-positive pediatric acute lymphoblastic leukemia at diagnosis. Am J Hematol. 2022 06 01; 97(6):E198-E201.  View on PubMed
  10. Francis SS, Ostrom QT, Cote DJ, Smith TR, Claus E, Barnholtz-Sloan JS. The Epidemiology of Central Nervous System Tumors. Hematol Oncol Clin North Am. 2022 02; 36(1):23-42.  View on PubMed
  11. Ostrom QT, Francis SS, Barnholtz-Sloan JS. Epidemiology of Brain and Other CNS Tumors. Curr Neurol Neurosci Rep. 2021 11 24; 21(12):68.  View on PubMed
  12. Liu R, Wu P, Ogrodzki P, Mahmoud S, Liang K, Liu P, Francis SS, Khalak H, Liu D, Li J, Ma T, Chen F, Liu W, Huang X, He W, Yuan Z, Qiao N, Meng X, Alqarni B, Quilez J, Kusuma V, Lin L, Jin X, Yang C, Anton X, Koshy A, Yang H, Xu X, Wang J, Xiao P, Al Kaabi N, Fasihuddin MS, Selvaraj FA, Weber S, Al Hosani FI, Liu S, Zaher WA. Publisher Correction: Genomic epidemiology of SARS-CoV-2 in the UAE reveals novel virus mutation, patterns of co-infection and tissue specific host immune response. Sci Rep. 2021 Sep 15; 11(1):18728.  View on PubMed
  13. Liu R, Wu P, Ogrodzki P, Mahmoud S, Liang K, Liu P, Francis SS, Khalak H, Liu D, Li J, Ma T, Chen F, Liu W, Huang X, He W, Yuan Z, Qiao N, Meng X, Alqarni B, Quilez J, Kusuma V, Lin L, Jin X, Yang C, Anton X, Koshy A, Yang H, Xu X, Wang J, Xiao P, Al Kaabi N, Fasihuddin MS, Selvaraj FA, Weber S, Al Hosani FI, Liu S, Zaher WA. Genomic epidemiology of SARS-CoV-2 in the UAE reveals novel virus mutation, patterns of co-infection and tissue specific host immune response. Sci Rep. 2021 07 07; 11(1):13971.  View on PubMed
  14. Eckel-Passow JE, Drucker KL, Kollmeyer TM, Kosel ML, Decker PA, Molinaro AM, Rice T, Praska CE, Clark L, Caron A, Abyzov A, Batzler A, Song JS, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Wiemels J, Wiencke JK, Francis S, Burns TC, Giannini C, Lachance DH, Wrensch M, Jenkins RB. Adult diffuse glioma GWAS by molecular subtype identifies variants in D2HGDH and FAM20C. Neuro Oncol. 2020 11 26; 22(11):1602-1613.  View on PubMed
  15. Francis SS, Wang R, Enders C, Prado I, Wiemels JL, Ma X, Metayer C. Socioeconomic status and childhood central nervous system tumors in California. Cancer Causes Control. 2021 Jan; 32(1):27-39.  View on PubMed
  16. Kachuri L, Francis SS, Morrison ML, Wendt GA, Bossé Y, Cavazos TB, Rashkin SR, Ziv E, Witte JS. The landscape of host genetic factors involved in immune response to common viral infections. Genome Med. 2020 10 27; 12(1):93.  View on PubMed
  17. Kachuri L, Francis SS, Morrison M, Wendt GA, Bossé Y, Cavazos TB, Rashkin SR, Ziv E, Witte JS. The landscape of host genetic factors involved in immune response to common viral infections. medRxiv. 2020 Sep 05.  View on PubMed
  18. Muskens IS, Feng Q, Francis SS, Walsh KM, Mckean-Cowdin R, Gauderman WJ, de Smith AJ, Wiemels JL. Pediatric glioma and medulloblastoma risk and population demographics: a Poisson regression analysis. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa089.  View on PubMed
  19. Enders C, Hyde RJ, Selvin S, Metayer C, Francis SS. ClustR: A Space-Time Cluster Analysis R Package for Individual-level Data. Epidemiology. 2020 03; 31(2):224-228.  View on PubMed
  20. Francis SS, Enders C, Hyde R, Gao X, Wang R, Ma X, Wiemels JL, Selvin S, Metayer C. Spatial-Temporal Cluster Analysis of Childhood Cancer in California. Epidemiology. 2020 03; 31(2):214-223.  View on PubMed

Go to UCSF Profiles, powered by CTSI