Research Summary

I am a Professor in Residence in the HIV, ID, and Global Medicine Division in the Department of Medicine.

Substance use plays important biological and behavioral roles in health outcomes, and my work consists of epidemiology at the intersection of substance use and infectious diseases. My research team is currently conducting several NIH-funded studies to examine the use of TB prophylaxis in HIV/TB co-infected alcohol users, as well as interventions to reduce drinking and increase antiretroviral therapy adherence. We are using novel biomarkers of alcohol consumption and INH pill-taking to gain objective measurements where self-report is problematic. I am also teaching and mentoring via a K-24 award, and grant-writing courses in Epidemiology and Biostatistics and the UCSF CTSI KL2 Scholars Program.

Research Funding

  • September 15, 2017 - August 31, 2022 - Interventions to reduce alcohol use and increase adherence to TB preventive therapy among HIV/TB co-infected drinkers (DIPT 1/2), Principal Investigator. Sponsor: NIH/NIAAA, Sponsor Award ID: U01AA026223
  • September 22, 2011 - August 31, 2021 - URBAN ARCH (3/5) Uganda Cohort TB preventive therapy for HIV-infected alcohol users in Uganda: an evaluation of safety tolerability and adherence, Principal Investigator. Sponsor: NIH/NIAAA, Sponsor Award ID: U01AA020776
  • April 1, 2017 - March 31, 2021 - Mobile technology to extend clinic-based counseling for HIV+s in Uganda, Principal Investigator. Sponsor: NIH/NIAAA, Sponsor Award ID: R01AA024990
  • September 15, 2013 - August 31, 2018 - Training in Research Program on Alcohol Use by Persons with our at Risk for HIV, Principal Investigator. Sponsor: NIH/NIAAA, Sponsor Award ID: K24AA022586

Education

Cornell University, Ithaca, NY, B.S., 5/1987, Statistics and Biometry
University of California, Berkeley, CA, M.A., 5/1989, Biostatistics
University of California, Berkeley, CA, Doctoral Student, 1989-1990, Biostatistics
University of California, Berkeley, CA, Ph.D., 5/2001, Epidemiology

Honors & Awards

  • 2009-2010
    Hellman Family Award for Early Career Faculty, UCSF
  • 2013-present
    NIH Center for Scientific Review: Behavioral and Social Science Approaches to Preventing HIV/AIDS (BSPH) Study Section ad hoc reviewer and Special Emphasis Panel reviewer (4 times) and Chair (2 times), Population and Public Health Approaches to HIV/ADS (PPAH) ad hoc reviewer (1 time)
  • 2015
    mHealth Summer Training Institute (UCLA) selected participant

Selected Publications

  1. Marcus GM, Vittinghoff E, Whitman IR, Joyce S, Yang V, Nah G, Gerstenfeld EP, Moss JD, Lee RJ, Lee BK, Tseng ZH, Vedantham V, Olgin JE, Scheinman MM, Hsia H, Gladstone R, Fan S, Lee E, Fang C, Ogomori K, Fatch R, Hahn JA. Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events. Ann Intern Med. 2021 Aug 31.  View on PubMed
  2. Nagata JM, Whittle HJ, Ganson KT, Tabler J, Hahn JA, Weiser SD. Food insecurity risk and alcohol use disorder in US young adults: Findings from the National Longitudinal Study of Adolescent to Adult Health. Am J Addict. 2021 Aug 29.  View on PubMed
  3. Tully DC, Hahn JA, Bean DJ, Evans JL, Morris MD, Page K, Allen TM. Identification of Genetically Related HCV Infections Among Self-Described Injecting Partnerships. Clin Infect Dis. 2021 Aug 27.  View on PubMed
  4. Gnatienko N, Calver K, Sullivan M, Forman LS, Heeren T, Blokhina E, Emenyonu N, Ventura AS, Tsui JI, Muyindike WR, Fatch R, Ngabirano C, Bridden C, Bryant K, Bazzi AR, Hahn JA. Heavy Alcohol Use Among Women and Men Living With HIV in Uganda, Russia, and the United States. J Stud Alcohol Drugs. 2021 07; 82(4):486-492.  View on PubMed
  5. Perkins JM, Kakuhikire B, Baguma C, Jurinsky J, Rasmussen JD, Satinsky EN, Namara E, Ahereza P, Kyokunda V, Perkins HW, Hahn JA, Bangsberg DR, Tsai AC. Overestimation of alcohol consumption norms as a driver of alcohol consumption: a whole-population network study of men across eight villages in rural, southwestern Uganda. Addiction. 2021 Jun 22.  View on PubMed
  6. Freiman JM, Fatch R, Cheng D, Emenyonu N, Ngabirano C, Geadas C, Adong J, Muyindike WR, Linas BP, Jacobson KR, Hahn JA. Prevalence of elevated liver transaminases and their relationship with alcohol use in people living with HIV on anti-retroviral therapy in Uganda. PLoS One. 2021; 16(6):e0250368.  View on PubMed
  7. Pierre F, Forman LS, Winter M, Cheng D, Ngabirano C, Emenyonu N, Hunt PW, Huang Y, Muyindike W, Samet J, Hahn JA, So-Armah K. Alcohol Consumption and Tryptophan Metabolism Among People with HIV Prior to Antiretroviral Therapy Initiation: The Uganda ARCH Cohort Study. Alcohol Alcohol. 2021 May 24.  View on PubMed
  8. Lodi S, Emenyonu NI, Marson K, Kwarisiima D, Fatch R, McDonell MG, Cheng DM, Thirumurthy H, Gandhi M, Camlin CS, Muyindike WR, Hahn JA, Chamie G. The Drinkers' Intervention to Prevent Tuberculosis (DIPT) trial among heavy drinkers living with HIV in Uganda: study protocol of a 2×2 factorial trial. Trials. 2021 May 20; 22(1):355.  View on PubMed
  9. Hahn JA, Murnane PM, Vittinghoff E, Muyindike WR, Emenyonu NI, Fatch R, Chamie G, Haberer JE, Francis JM, Kapiga S, Jacobson K, Myers B, Couture MC, DiClemente RJ, Brown JL, So-Armah K, Sulkowski M, Marcus GM, Woolf-King S, Cook RL, Richards VL, Molina P, Ferguson T, Welsh D, Piano MR, Phillips SA, Stewart S, Afshar M, Page K, McGinnis K, Fiellin DA, Justice AC, Bryant K, Saitz R. Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta-analysis. Alcohol Clin Exp Res. 2021 06; 45(6):1166-1187.  View on PubMed
  10. Aschbacher K, Hendershot CS, Tison G, Hahn JA, Avram R, Olgin JE, Marcus GM. Machine learning prediction of blood alcohol concentration: a digital signature of smart-breathalyzer behavior. NPJ Digit Med. 2021 Apr 20; 4(1):74.  View on PubMed
  11. Puryear SB, Fatch R, Beesiga B, Kekibiina A, Lodi S, Marson K, Emenyonu NI, Muyindike WR, Kwarisiima D, Hahn JA, Chamie G. Higher Levels of Alcohol Use Are Associated With Latent Tuberculosis Infection in Adults Living With Human Immunodeficiency Virus. Clin Infect Dis. 2021 03 01; 72(5):865-868.  View on PubMed
  12. Leddy AM, Hahn JA, Getahun M, Emenyonu NI, Woolf-King SE, Sanyu N, Katusiime A, Fatch R, Chander G, Hutton HE, Muyindike WR, Camlin CS. Cultural Adaptation of an Intervention to Reduce Hazardous Alcohol Use Among People Living with HIV in Southwestern Uganda. AIDS Behav. 2021 Feb 15.  View on PubMed
  13. Metcalfe J, Bacchetti P, Esmail A, Reckers A, Aguilar D, Wen A, Huo S, Muyindike WR, Hahn JA, Dheda K, Gandhi M, Gerona R. Diagnostic accuracy of a liquid chromatography-tandem mass spectrometry assay in small hair samples for rifampin-resistant tuberculosis drug concentrations in a routine care setting. BMC Infect Dis. 2021 Jan 22; 21(1):99.  View on PubMed
  14. Richards VL, Sajdeya R, Villalba K, Wang Y, Bryant V, Brumback B, Bryant K, Hahn JA, Cook RL. Secondary Analysis of a Randomized Clinical Trial of Naltrexone Among Women Living With HIV: Correlations Between Reductions in Self-Reported Alcohol Use and Changes in Phosphatidylethanol. Alcohol Clin Exp Res. 2021 01; 45(1):174-180.  View on PubMed
  15. Wagman JA, Nabukalu D, Miller AP, Wawer MJ, Ssekubugu R, Nakowooya H, Nantume B, Park E, Hahn JA, Serwadda DM, Sewankambo NK, Nalugoda F, Kigozi G. Prevalence and correlates of men's and women's alcohol use in agrarian, trading and fishing communities in Rakai, Uganda. PLoS One. 2020; 15(10):e0240796.  View on PubMed
  16. Muyindike WR, Fatch R, Cheng DM, Emenyonu NI, Ngabirano C, Adong J, Linas BP, Jacobson KR, Hahn JA. Tuberculin skin test positivity among HIV-infected alcohol drinkers on antiretrovirals in south-western Uganda. PLoS One. 2020; 15(7):e0235261.  View on PubMed
  17. Foley JD, Sheinfil A, Woolf-King SE, Fatch R, Emenyonu NI, Muyindike WR, Kekibiina A, Ngabirano C, Samet JH, Cheng DM, Hahn JA. Assessing the interaction between depressive symptoms and alcohol use prior to antiretroviral therapy on viral suppression among people living with HIV in Rural Uganda. AIDS Care. 2020 10; 32(10):1251-1257.  View on PubMed
  18. Conroy AA, Ruark A, McKenna SA, Tan JY, Darbes LA, Hahn JA, Mkandawire J. The Unaddressed Needs of Alcohol-Using Couples on Antiretroviral Therapy in Malawi: Formative Research on Multilevel Interventions. AIDS Behav. 2020 Jun; 24(6):1599-1611.  View on PubMed
  19. Leyva Y, Page K, Shiboski S, Hahn JA, Evans J, Erhardt E. Per-Contact Infectivity of Hepatitis C Virus Acquisition in Association With Receptive Needle Sharing Exposures in a Prospective Cohort of Young Adult People who Inject Drugs in San Francisco, California. Open Forum Infect Dis. 2020 Apr; 7(4):ofaa092.  View on PubMed
  20. Puryear SB, Balzer LB, Ayieko J, Kwarisiima D, Hahn JA, Charlebois ED, Clark TD, Cohen CR, Bukusi EA, Kamya MR, Petersen ML, Havlir DV, Chamie G. Associations between alcohol use and HIV care cascade outcomes among adults undergoing population-based HIV testing in East Africa. AIDS. 2020 03 01; 34(3):405-413.  View on PubMed

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