Research Summary

I am a Professor in Residence in the HIV, ID, and Global Medicine Division in the Department of Medicine.

Substance use plays important biological and behavioral roles in health outcomes, and my work consists of epidemiology at the intersection of substance use and infectious diseases. My research team is currently conducting several NIH-funded studies to examine the use of TB prophylaxis in HIV/TB co-infected alcohol users, as well as interventions to reduce drinking and increase antiretroviral therapy adherence. We are using novel biomarkers of alcohol consumption and INH pill-taking to gain objective measurements where self-report is problematic. I am also teaching and mentoring via a K-24 award, and grant-writing courses in Epidemiology and Biostatistics and the UCSF CTSI KL2 Scholars Program.

Research Funding

  • June 1, 2024 - May 31, 2027 - The Phosphatidylethanol (PEth) Results Communication (PERC) Study , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R34AA031652
  • September 10, 2021 - August 31, 2026 - The International Uganda Russia Boston Alcohol Network for Alcohol Research Collaboration on HIV/AIDS (URBAN ARCH) Center , Co-Investigator; Uganda project PI . Sponsor: NIH, Sponsor Award ID: P01AA029541
  • May 1, 2022 - February 28, 2025 - Biomarkers for Alcohol/HIV Research (BAHR) Study , Principal Investigator . Sponsor: NIH, Sponsor Award ID: NIH R01AA029962
  • September 15, 2013 - April 30, 2024 - Training in Research Program on Alcohol Use by Persons with our at Risk for HIV , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K24AA022586
  • September 15, 2017 - August 31, 2022 - Interventions to reduce alcohol use and increase adherence to TB preventive therapy among HIV/TB co-infected drinkers (DIPT 1/2) , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01AA026223
  • September 20, 2011 - August 31, 2022 - URBAN ARCH (3/5) Uganda Cohort TB preventive therapy for HIV-infected alcohol users in Uganda: an evaluation of safety tolerability and adherence , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01AA020776
  • April 1, 2017 - March 31, 2021 - Mobile technology to extend clinic-based counseling for HIV+s in Uganda , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AA024990
  • July 15, 2010 - March 31, 2015 - Changes in Alcohol Consumption in HIV Positives in Uganda , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AA018631
  • June 20, 2007 - May 31, 2012 - Dynamic Modeling of the HCV Epidemic in IDU , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K01DA023365
  • September 30, 2006 - August 31, 2009 - Measurement of Alcohol Use Among HIV-Positives in Uganda , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21AA015897

Education

Cornell University, Ithaca, NY, B.S., 5/1987, Statistics and Biometry
University of California, Berkeley, CA, M.A., 5/1989, Biostatistics
University of California, Berkeley, CA, Doctoral Student, 1989-1990, Biostatistics
University of California, Berkeley, CA, Ph.D., 5/2001, Epidemiology

Honors & Awards

  • 2009-2010
    Hellman Family Award for Early Career Faculty, UCSF
  • 2013-present
    NIH Center for Scientific Review: Behavioral and Social Science Approaches to Preventing HIV/AIDS (BSPH) Study Section ad hoc reviewer and Special Emphasis Panel reviewer (4 times) and Chair (2 times), Population and Public Health Approaches to HIV/ADS (PPAH) ad hoc reviewer (1 time)
  • 2015
    mHealth Summer Training Institute (UCLA) selected participant

Selected Publications

  1. Abbott R, Landsiedel K, Atukunda M, Puryear SB, Chamie G, Hahn JA, Mwangwa F, Kakande E, Petersen ML, Havlir DV, Charlebois E, Balzer LB, Kamya MR, Marquez C. Incident Tuberculosis Infection Is Associated With Alcohol Use in Adults in Rural Uganda. Clin Infect Dis. 2025 Mar 17; 80(3):562-565.  View on PubMed
  2. Mkandawire J, Ssewamala FM, Hahn JA, Mulauzi N, Neilands TB, Tebbetts S, Darbes LA, Brown DS, Conroy AA. Economic and relationship-strengthening intervention to reduce alcohol use in couples living with HIV in Malawi: a study protocol for a randomised controlled trial of Mlambe. BMJ Open. 2025 Feb 10; 15(2):e097247.  View on PubMed
  3. Muyindike WR, Fatch R, Lodi S, Emenyonu NI, Kekibiina A, Adong J, Beesiga B, Marson K, Thirumurthy H, McDonell MG, Kamya MR, Chamie G, Hahn JA. Alcohol use and HIV suppression after completion of financial incentives for alcohol abstinence and isoniazid adherence: a randomized controlled trial. EClinicalMedicine. 2025 Feb; 80:103045.  View on PubMed
  4. Hahn JA, Piano MR, Hwang CL, Justice AC. Phosphatidylethanol Can Improve Detection and Treatment of Unhealthy Alcohol Use. Am J Prev Med. 2025 Mar; 68(3):638-641.  View on PubMed
  5. Murnane PM, Afshar M, Chamie G, Cook RL, Ferguson T, Haque LY, Jacobson KR, Justice AC, Kim TW, Khalili M, Krupitsky E, McGinnis KA, Molina P, Muyindike WR, Myers B, Richards VL, So-Armah K, Stewart S, Sulkowski MS, Tien PC, Hahn JA. Using Phosphatidylethanol as an Adjunct to Self-Reported Alcohol Use Improves Identification of Liver Fibrosis Risk. Am J Gastroenterol. 2024 Oct 31.  View on PubMed
  6. Conroy AA, Ruark A, Mulauzi N, Mkandawire J, Darbes LA, Hahn JA, Neilands TB, Tebbetts S, Ssewamala FM. Mlambe economic and relationship-strengthening intervention for alcohol use decreases violence and improves relationship quality in couples living with HIV in Malawi. Soc Sci Med. 2024 Dec; 362:117407.  View on PubMed
  7. Jain JP, Ma Y, Dawson-Rose C, Santos GM, Han A, Price J, Hahn JA, Tien PC. The prevalence and correlates of biomarker positive unhealthy alcohol use among women living with and without HIV in San Francisco, California. PLoS One. 2024; 19(10):e0308867.  View on PubMed
  8. Odokonyero RF, Nakasujja N, Turiho A, Sanyu N, Muyindike WR, Nansera D, Semitala F, Kamya MR, Katahoire AR, Hahn JA, Camlin CC, Muhwezi WW. Provider perceptions of young people living with HIV and unhealthy alcohol use in Southwestern Uganda: a qualitative study. Addict Sci Clin Pract. 2024 Sep 02; 19(1):62.  View on PubMed
  9. Savinkina A, Muyindike W, Hahn JA, Emenyonu NI, Fatch R, Ngabirano C, Adong J, Jacobson KR, Linas BP. Strategies for isoniazid preventive therapy in HIV-positive patients who consume alcohol. Int J Tuberc Lung Dis. 2024 Jul 01; 28(7):335-342.  View on PubMed
  10. Espinosa da Silva C, Fatch R, Emenyonu N, Muyindike W, Adong J, Rao SR, Chamie G, Ngabirano C, Tumwegamire A, Kekibiina A, Marson K, Beesiga B, Sanyu N, Katusiime A, Hahn JA. Psychometric assessment of the Runyankole-translated Marlowe-Crowne Social Desirability Scale among persons with HIV in Uganda. BMC Public Health. 2024 06 19; 24(1):1628.  View on PubMed
  11. Asiimwe SB, Kekibiina A, Woolf-King SE, Fatch R, Emenyonu N, Hahn JA. Alcohol Consumption Among Persons Living with HIV: Perceptions, Messages and Interventions-A Qualitative Study at an HIV Treatment Clinic in South Western Uganda. AIDS Behav. 2024 Aug; 28(8):2559-2576.  View on PubMed
  12. Appa A, Miller AP, Fatch R, Kekibiina A, Beesiga B, Adong J, Emenyonu N, Marson K, Getahun M, Kamya M, Muyindike W, McDonell M, Thirumurthy H, Hahn JA, Chamie G, Camlin CS. Participant perspectives on incentives for TB preventative therapy adherence and reduced alcohol use: A qualitative study. PLOS Glob Public Health. 2024; 4(4):e0002472.  View on PubMed
  13. Conroy AA, Hahn JA, Neilands TB, Darbes LA, Tebbetts S, Mulauzi N, Mkandawire J, Ssewamala FM. Pilot Trial Results of Mlambe: An Economic and Relationship-Strengthening Intervention to Address Heavy Drinking and Adherence to Antiretroviral Therapy in Malawi. AIDS Behav. 2024 Jul; 28(7):2296-2306.  View on PubMed
  14. Tumwegamire A, Fatch R, Emenyonu NI, Lodi S, Muyindike WR, Kekibiina A, Adong J, Ngabirano C, Beesiga B, Marson K, Golabi N, Kamya M, Chamie G, Hahn JA. Association between smoking and lack of HIV virological suppression in a cross-sectional study of persons with HIV on antiretroviral therapy in Uganda. PLoS One. 2024; 19(3):e0300508.  View on PubMed
  15. Msimango L, Butterfield R, Starks TJ, van Heerden A, Neilands TB, Hahn JA, Chibi B, Humphries H, Conroy AA. Couples motivational interviewing with mobile breathalysers to reduce alcohol use in South Africa: a pilot randomised controlled trial of Masibambisane. BMJ Open. 2024 01 30; 14(1):e083390.  View on PubMed
  16. Miller AP, Appa A, Muyindike W, Fatch R, Kekibiina A, Beesiga B, Adong J, Emenyonu N, Marson K, Getahun M, Kamya M, Chamie G, Camlin CS, Hahn JA. A Qualitative Exploration of Intimate Partner Violence Among HIV/TB Coinfected Persons With Problematic Alcohol Use Participating in an Incentive-Based Alcohol/Medication Adherence Intervention in Uganda During COVID-19. Violence Against Women. 2025 Apr; 31(5):1082-1103.  View on PubMed
  17. Odokonyero RF, Fatch R, Emenyonu NI, Cheng DM, Ngabirano C, Adong J, Muyindike WR, Nakasujja N, Camlin CS, Kamya M, Hahn JA. The Relationship between Age at Initiation of Regular Drinking of Alcohol and Viral Suppression Status, and Depression Symptoms Among People Living with HIV in South-Western Uganda. AIDS Behav. 2024 Apr; 28(4):1415-1422.  View on PubMed
  18. Puryear SB, Mwangwa F, Opel F, Chamie G, Balzer LB, Kabami J, Ayieko J, Owaraganise A, Kakande E, Agengo G, Bukusi E, Kabageni S, Omoding D, Bacon M, Schrom J, Woolf-King S, Petersen ML, Havlir DV, Kamya M, Hahn JA. Effect of a brief alcohol counselling intervention on HIV viral suppression and alcohol use among persons with HIV and unhealthy alcohol use in Uganda and Kenya: a randomized controlled trial. J Int AIDS Soc. 2023 12; 26(12):e26187.  View on PubMed
  19. Chamie G, Hahn JA, Kekibiina A, Emenyonu NI, Beesiga B, Marson K, Fatch R, Lodi S, Adong J, Thirumurthy H, McDonell MG, Gandhi M, Bryant K, Havlir DV, Kamya MR, Muyindike WR. Financial incentives for reduced alcohol use and increased isoniazid adherence during tuberculosis preventive therapy among people with HIV in Uganda: an open-label, factorial randomised controlled trial. Lancet Glob Health. 2023 Dec; 11(12):e1899-e1910.  View on PubMed
  20. Tierney HR, Ma Y, Bacchetti P, Adimora AA, Chandran A, Kempf MC, Collins LF, DeHovitz J, DiClemente RJ, French AL, Jones DL, Sharma A, Spence AB, Hahn JA, Price JC, Tien PC. Pivoting from in-person to phone survey assessment of alcohol and substance use: effects on representativeness in a United States prospective cohort of women living with and without HIV. Am J Drug Alcohol Abuse. 2024 Jan 02; 50(1):54-63.  View on PubMed

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