Program Leaders



Education and Training Liaison: Gideon St. Helen, PhD

Community Engagement Liaison: Nynikka Palmer, DrPH, MPH

The overarching vision of the Cancer Control Program is focus on the multilevel causes of cancer from genes to society, including social determinants of cancer and exposures influenced by industry, in order to develop and implement effective behavioral, clinical and policy interventions that will reduce the burden of cancer in our UCSF catchment area and beyond and achieve health equity in cancer outcomes. 

> FAQ: Cancer and Tobacco Control Site Committee to support Interventional Clinical Trials

The Program aims to develop, implement, and disseminate research that will reduce cancer risk, incidence, morbidity, and mortality, and improve the quality of care and life for all people with cancer. Building on the foundation of the diverse population and innovative spirit of the San Francisco Bay Area and Northern California, the Program conducts cancer control research with broad impact in Northern California and beyond. The Program's transdisciplinary approach enables members to collaborate with one another, other HDFCCC Programs and Shared Resources, community partners, healthcare systems, and policy makers. The Program has a specific focus to address cancer disparities.

Novel approaches to better understand the causes and risks of cancer to inform interventions

Laura Fejerman, PhD and Elad Ziv, MD, PhD discovered variations in susceptibility to breast cancer in a genome-wide association study (GWAS) of Latinas using Ancestral Informative Markers that revealed that Native Americans are at highest risk. Their work was published in Nature Communications and covered by the New York Times, Washington Post, and TIME. Another example was work to assess the etiology of postmenopausal breast cancer using a novel complex modeling approach. Hiatt with Allan Balmain, PhD, FRSDejana Braithwaite, MS, PhDMark Moasser, MD; and Zena Werb, PhD took a transdisciplinary approach to incorporate evidence of both the strength of association and the quality of the evidence, operationalizing it through a mathematical simulation; this work was published in Cancer Epidemiology, Biomarkers, and Prevention.

 

Developing and testing interventions to translate what is known about cancer prevention into practice

Highlights include two randomized controlled trials (RCTs) conducted by Tung Nguyen, MDJanice Tsoh, PhDRena Pasick, DrPH; and Susan Stewart, PhD (UC Davis) showing that lay health workers (LHWs) were highly effective in promoting colorectal cancer (CRC) screening among Chinese and Vietnamese Americans, two large populations in the HDFCCC catchment area. This work led to an NCI-funded grant with UC Davis, UCLA, and University of Hawaii that successfully tested similar approaches among Filipino, Hmong, and Korean Americans. Another high-impact study was led by Michael Potter, MD and Judith Walsh, MD, MPH, who created and studied a highly innovative and effective FLU-FIT program, an NCI Research-Tested Intervention Program, which combined the delivery of CRC screening with annual flu shot campaigns. They successfully implemented FLU-FIT at Kaiser Permanente, a major healthcare organization in the catchment area with over three million members, in an RCT with over 6,200 participants. ACS has adopted and branded FLU-FIT, and ACS staff and others have promoted and implemented it in community health centers and hospitals in nearly all 50 states and in tribal and migrant worker communities. For cervical cancer screening, George Sawaya, MD led a national effort to revise recommendations, authored the American College of Physicians’ guidelines, and was a key contributor to the US Preventive Services Task Force (USPSTF) recommendations.

 

Addressing crucial challenges in the care of cancer patients and survivors

Eleni Linos, MD, DrPH and Mary-Margaret Chren, MD contributed to an important emerging area, over-diagnosis of cancer, by providing guidelines in a JAMA article on the diagnosis of basal cell carcinoma among patients with limited life expectancy. Michael Rabow, MD, a pre-eminent researcher in symptom management and palliative care, along with colleagues from Roswell Park, Moffitt, and Stanford Cancer Centers, surveyed 22 cancer centers in the National Comprehensive Cancer Network (NCCN) and found that most provided palliative care in a setting where demand exceeded capacity, and that opportunities exist to expand palliative care for patients with hematologic malignancies. Anna Nápoles, MPH, PhD showed that a community-based, translational stress management program delivered by peer educators improved health-related quality of life in Spanish-speaking Latinas with breast cancer.

Roster of Cancer Control Program

Total: 82 members.

For details on membership criteria, please see our membership page.