Michelle Hermiston, MD, PhD

Education

University of Iowa, B.S August, 1988, Physiology
Washington University School of Medicine, Ph.D., May, 1997, Developmental Biology
Washington University School of Medicine, M.D., May, 1997, Medicine
University of California, San Francisco, Resident, 1997-99, Pediatrics
University of California, San Francisco, Fellow, 1999-03, Hematology/Oncology
University of California, San Francisco, Post-Doctoral Fellow,2001-2007,Immunology

Honors & Awards

• 1987
  Mortar Board Honor Society, University of Iowa
• 1988
  Honors Graduate, University of Iowa
• 1988
  University of Iowa Homecoming Award for Excellence in Scholarship, Leadership, and Service
• 1990
  Medical Scientist Training Program Fellowship, Washington University
• 1990
  Edmond V. Cowdry Prize in Histology, Washington University
• 1993
  Spencer T. and Ann W. Olin Foundation Medical Scientist Fellowship, Washington University
• 1995
  Barbara Jackshik Award for Excellence in the Field of Cellular Regulation, Washington University
• 1996
  American College of Physicians Award for Excellence in Physical Diagnosis
• 1997
  American Medical Women's Association Janet M. Glasgow Memorial Achievement Citation, presented to women graduating in the top ten percent of their medical school class
• 1997
  Missouri State Medical Association Award for Outstanding Achievement in Medicine
• 1997
  Alpha Omega Alpha, Washington University School of Medicine
• 1997
  UCSF Molecular Medicine Research Fellowship Program
• 2001
  Molecular Oncology Investigator, University of California San Francisco Cancer Center
• 2004
  FASEB Summer Protein Phosphatase Research Conference Poster Award
• 2005
  Nominee, Department of Pediatrics Housestaff Teaching Award, UCSF
• 2007-10
  Nominee, Fellow Mentoring Award, Department of Pediatrics, UCSF
• 2008
  St. Baldrick's Foundation, Young Investigator Career Development Award
• 2009
  Alex Lemonade Stand Young Investigator Career Development Award
• 2010
  Histiocyte Society Nezelof Prize in Basic Science

Selected Publications

1. Hermiston ML Double trouble for Langerhans cell histiocytosis.  View on PubMed
2. Michael W Boyer, Sonali Chaudhury, Kara L Davis, Timothy Alan Driscoll, Stephan Grupp, Michelle Hermiston, Samuel John, Amy K Keating, Christina Kovacs, Andrea Magley, G. Doug Myers, Christine L Phillips, Mike A. Pulsipher, Das Purkayastha, Julie-An Talano, Olufolake A Adisa, Jennifer Willert 149 Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion Following Loss of B-Cell Aplasia in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia: HESTER Phase II Study.  View on PubMed
3. Chaturvedi V, Marsh RA, Lorenz AZ, Owsley E, Chaturvedi V, Nguyen T, Goldman J, Henry MM, Greenberg J, Ladisch S, Hermiston ML, Jeng MR, Naqvi A, Allen CE, Wong HR, Jordan MB T cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis.  View on PubMed
4. David T. Teachey, Meenakshi Devidas, Brent L Wood, Zhiguo Chen, Robert James Hayashi, Robert D Annett, Barbara L Asselin, Keith J August, Steve Y Cho, Kimberly P. Dunsmore, Brian T. Fisher, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Michelle L. Hermiston, Terzah M Horton, Alok I Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I Patel, Eric S. Schafer, Tal Schechter-Finkelstein, Kristin A. Shimano, Neelam Singh, Amii C. Steele, Maria L. Sulis, Sarah L Vargas, Stuart S. Winter, Charlotte Wood, Patrick Zweider McKay, Catherine M. Bollard, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL  View on PubMed
5. Michael W Boyer, Sonali Chaudhury, Kara L Davis, Timothy Alan Driscoll, Stephan A Grupp, Michelle Hermiston, Samuel John, Amy K Keating, Christina Kovacs, Andrea Magley, Gary Douglas Myers, Christine L Phillips, Michael A Pulsipher, Das Purkayastha, Julie-An Talano, Jennifer Willert HESTER: A Phase II Study Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia Experiencing Loss of B-Cell Aplasia.  View on PubMed
6. Alan S. Wayne, Gerard Michel, Daniel W. Lee, André Baruchel, Sonali Chaudhury, Patrick A. Brown, Michelle Hermiston, Joerg Krueger, Tong Shen, Kristy Tailford, Behzad Kharabi Masouleh ZUMA-4: A Phase 1/2 Multicenter Study of KTE-X19 in Pediatric and Adolescent Patients With Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma.  View on PubMed
7. Smith GA, Levinson AL, Galvin RT, Lalor LE, McCalmont T, Wang L, Geis MC, Odegaard K, Hupp M, Maguiness S, Turcotte LM, Cordoro KM, Hermiston ML Concurrent Subcutaneous Panniculitis-like T-Cell Lymphoma and B-Cell Acute Lymphoblastic Leukemia in 2 Pediatric Patients.  View on PubMed
8. Meyer LK, Verbist KC, Albeituni S, Scull BP, Bassett RC, Stroh AN, Tillman H, Allen CE, Hermiston ML, Nichols KE JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation.  View on PubMed
9. Hayashi RJ, Winter SS, Dunsmore KP, Devidas M, Chen Z, Wood BL, Hermiston ML, Teachey DT, Perkins SL, Miles RR, Raetz EA, Loh ML, Winick NJ, Carroll WL, Hunger SP, Lim MS, Gross TG, Bollard CM Successful Outcomes of Newly Diagnosed T Lymphoblastic Lymphoma: Results From Children's Oncology Group AALL0434.  View on PubMed
10. Meyer LK, Huang BJ, Delgado-Martin C, Roy RP, Hechmer A, Wandler AM, Vincent TL, Fortina P, Olshen AB, Wood BL, Horton TM, Shannon KM, Teachey DT, Hermiston ML Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes.  View on PubMed
11. Burke MJ, Kostadinov R, Sposto R, Gore L, Kelley SM, Rabik C, Trepel JB, Lee MJ, Yuno A, Lee S, Bhojwani D, Jeha S, Chang BH, Sulis ML, Hermiston ML, Gaynon P, Huynh V, Verma A, Gardner R, Heym KM, Dennis RM, Ziegler DS, Laetsch TW, Oesterheld JE, Dubois SG, Pollard JA, Glade-Bender J, Cooper TM, Kaplan JA, Farooqi MS, Yoo B, Guest E, Wayne AS, Brown PA Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study.  View on PubMed
12. Lauren K. Meyer, Cristina Delgado-Martin, Phillip P. Sharp, Dustin McMinn, Christopher J. Kirk, Jack Taunton, Michelle L. Hermiston Protein Translocation Inhibitors Overcome Cytokine-Induced Glucocorticoid Resistance in T-Cell Acute Lymphoblastic Leukemia.  View on PubMed
13. Aleksandra S. Dain, Michelle L. Hermiston, Kristin A. Shimano, Sandhya Kharbanda, Alexis Melton, Jasmeen Dara, James N Huang, Christopher C. Dvorak Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis.  View on PubMed
14. Lauren K. Meyer, Katherine Verbist, Sabrin Albeituni, Rachel Bassett, Michelle L. Hermiston, Kim E. Nichols The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis.  View on PubMed
15. Jordan MB, Allen CE, Greenberg J, Henry M, Hermiston ML, Kumar A, Hines M, Eckstein O, Ladisch S, Nichols KE, Rodriguez-Galindo C, Wistinghausen B, McClain KL Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: Recommendations from the North American Consortium for Histiocytosis (NACHO).  View on PubMed
16. Meyer LK, Delgado-Martin C, Maude SL, Shannon KM, Teachey DT, Hermiston ML CRLF2 rearrangement in Ph-like acute lymphoblastic leukemia predicts relative glucocorticoid resistance that is overcome with MEK or Akt inhibition.  View on PubMed
17. Zinter MS, Hermiston ML Calming the storm in HLH.  View on PubMed
18. A.S. Wayne, V. Huynh, N. Hijiya, R. Rouce, P.A. Brown, J. Krueger, M. Rytting, C.L. Kitko, E. Dela Ziga, M. Hermiston, M.K. Richards, A. Baruchel, T. Shen, L. Goyal, R. Vezan, R. Jain, D.W. Lee PS962 PHASE 1 RESULTS OF ZUMA-4: KTE-X19, AN ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY, IN PEDIATRIC AND ADOLESCENT PATIENTS WITH RELAPSED/REFRACTORY B CELL ACUTE LYMPHOBLASTIC LEUKEMIA.  View on PubMed
19. Lauren K. Meyer, Cristina Delgado-Martin, Ritu Roy, Benjamin J. Huang, Tiffaney Vincent, Adam Olshen, Brent L. Wood, Yu Liu, Jinghui Zhang, Charles Grenfell Mullighan, Terzah M. Horton, Mignon L. Loh, Meenakshi Devidas, Elizabeth A. Raetz, Robert J. Hayashi, Stuart Winter, Kimberly P. Dunsmore, Stephen Hunger, David T. Teachey, Michelle L. Hermiston Gene expression signature associated with in vitro dexamethasone resistance and post-induction minimal residual disease in pediatric T-cell acute lymphoblastic leukemia.  View on PubMed
20. Burkhardt B, Hermiston ML Lymphoblastic lymphoma in children and adolescents: review of current challenges and future opportunities.  View on PubMed

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