Research Funding

  • May 4, 2015 - April 30, 2020 - Improving risk allocation and developing novel therapies for children with T-ALL, Co-Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R01CA193776
  • June 1, 2010 - May 31, 2015 - Interplay of Innate and Adaptive Immunity in Lupus Pathogenesis, Principal Investigator. Sponsor: NIH/NIAID, Sponsor Award ID: R01AI089831
  • July 11, 2003 - June 30, 2007 - Role of CD45 in Hematopoiesis and Lymphomagenesis, Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: K08CA098418
  • May 4, 2015 - April 30, 2020 - Improving risk allocation and developing novel therapies for children with T-ALL, Co-Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R01CA193776

Education

University of Iowa, B.S August, 1988, Physiology
Washington University School of Medicine, Ph.D., May, 1997, Developmental Biology
Washington University School of Medicine, M.D., May, 1997, Medicine
University of California, San Francisco, Resident, 1997-99, Pediatrics
University of California, San Francisco, Fellow, 1999-03, Hematology/Oncology
University of California, San Francisco, Post-Doctoral Fellow,2001-2007,Immunology

Honors & Awards

  • 1987
    Mortar Board Honor Society, University of Iowa
  • 1988
    Honors Graduate, University of Iowa
  • 1988
    University of Iowa Homecoming Award for Excellence in Scholarship, Leadership, and Service
  • 1990
    Medical Scientist Training Program Fellowship, Washington University
  • 1990
    Edmond V. Cowdry Prize in Histology, Washington University
  • 1993
    Spencer T. and Ann W. Olin Foundation Medical Scientist Fellowship, Washington University
  • 1995
    Barbara Jackshik Award for Excellence in the Field of Cellular Regulation, Washington University
  • 1996
    American College of Physicians Award for Excellence in Physical Diagnosis
  • 1997
    American Medical Women's Association Janet M. Glasgow Memorial Achievement Citation, presented to women graduating in the top ten percent of their medical school class
  • 1997
    Missouri State Medical Association Award for Outstanding Achievement in Medicine
  • 1997
    Alpha Omega Alpha, Washington University School of Medicine
  • 1997
    UCSF Molecular Medicine Research Fellowship Program
  • 2001
    Molecular Oncology Investigator, University of California San Francisco Cancer Center
  • 2004
    FASEB Summer Protein Phosphatase Research Conference Poster Award
  • 2005
    Nominee, Department of Pediatrics Housestaff Teaching Award, UCSF
  • 2007-10
    Nominee, Fellow Mentoring Award, Department of Pediatrics, UCSF
  • 2008
    St. Baldrick's Foundation, Young Investigator Career Development Award
  • 2009
    Alex Lemonade Stand Young Investigator Career Development Award
  • 2010
    Histiocyte Society Nezelof Prize in Basic Science

Selected Publications

  1. Fabrizio VA, Phillips CL, Lane A, Baggott C, Prabhu S, Egeler E, Mavroukakis S, Pacenta HL, Rossoff J, Stefanski H, Talano JA, Moskop A, Margossian SP, Verneris MR, Myers GD, Karras NA, Brown PA, Qayed M, Hermiston ML, Satwani P, Krupski C, Keating AK, Wilcox R, Rabik CA, Chinnabhandar V, Kunicki M, Goksenin AY, Curran KJ, Mackall CL, Laetsch TW, Schultz LM. Tisagenlecleucel Outcomes in Relapsed/Refractory Extramedullary ALL: A Pediatric Real World CAR Consortium Report. Blood Adv. 2021 Nov 18.  View on PubMed
  2. Fabrizio VA, Boelens JJ, Mauguen A, Baggott C, Prabhu S, Egeler E, Mavroukakis S, Pacenta HL, Phillips CL, Rossoff J, Stefanski H, Talano JA, Moskop A, Margossian SP, Verneris MR, Myers GD, Karras NA, Brown PA, Qayed M, Hermiston ML, Satwani P, Krupski C, Keating AK, Wilcox R, Rabik CA, Chinnabhandar V, Kunicki M, Goksenin AY, Mackall CL, Laetsch TW, Schultz LM, Curran KJ. Optimal fludarabine lymphodepletion is associated with improved outcomes following CAR T-cell Therapy. Blood Adv. 2021 Nov 17.  View on PubMed
  3. Paul Harker-Murray, Brent L. Wood, Meenakshi Devidas, Zhiguo Chen, Tal Schechter-Finkelstein, Robert J. Hayashi, Keith J August, Kimberly P. Dunsmore, Michelle L. Hermiston, Terzah M. Horton, Yoav H. Messinger, Sarah L Vargas, Eric S Schafer, Maria Luisa Sulis, Stuart S. Winter, Charlotte Wood, Catherine M Bollard, Mignon L. Loh, Stephen P Hunger, Elizabeth A. Raetz, David T. Teachey. Intensification of Chemotherapy Using a Modified BFM Backbone for Children, Adolescents and Young Adults with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL) Identifies Highly Chemorefractory Patients Who Benefit from Allogeneic Hematopoietic Stem Cell Transplantation. Blood. 2021 Nov 5; 138(Supplement 1):3487-3487.  View on PubMed
  4. Nirali N. Shah, Eric S Schafer, Kenneth Matthew Heym, Andrew E. Place, Melissa A. Burns, Nathan Gossai, Peter Shaw, Michael J. Burke, Bill H. Chang, Michelle L. Hermiston, Reuven J Schore, Teresa Rushing, Paul F Jarosinski, Richard Sposto, Ellynore Florendo, Jemily Malvar, Yueh-Yun Chi, James A. Whitlock, Lewis B. Silverman, Deepa Bhojwani, Alan S. Wayne. Vincristine Sulfate Liposome Injection (VSLI, Marqibo®) in Combination with UK ALL-R3 Induction Chemotherapy for Children, Adolescents and Young Adults with Relapsed Acute Lymphoblastic Leukemia (ALL): A Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium Trial. Blood. 2021 Nov 5; 138(Supplement 1):3402-3402.  View on PubMed
  5. Fitch B, Zhou M, Situ J, Surianarayanan S, Reeves MQ, Hermiston ML, Wiemels JL, Kogan SC. Decreased IL-10 accelerates B-cell leukemia/lymphoma in a mouse model of pediatric lymphoid leukemia. Blood Adv. 2021 Nov 02.  View on PubMed
  6. Collins GS, Beaman H, Ho AM, Hermiston ML, Cohen HJ, Dzeng EW. Perceptions of specialty palliative care and its role in pediatric stem cell transplant: A multidisciplinary qualitative study. Pediatr Blood Cancer. 2021 Oct 27; e29424.  View on PubMed
  7. Lin H, Scull BP, Goldberg BR, Abhyankar HA, Eckstein OE, Zinn DJ, Lubega J, Agrusa J, El Mallawaney N, Gulati N, Forbes L, Chinn I, Chakraborty R, Velasquez J, Goldman J, Bashir D, Lam F, Muscal E, Henry MM, Greenberg JN, Ladisch S, Hermiston ML, Meyer LK, Jeng M, Naqvi A, McClain K, Nguyen T, Wong H, Man TK, Jordan MB, Allen CE. IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS. Blood Adv. 2021 Sep 14; 5(17):3457-3467.  View on PubMed
  8. Rossoff J, Baggott C, Prabhu S, Pacenta HL, Phillips CL, Stefanski H, Talano JA, Moskop A, Margossian SP, Verneris MR, Myers GD, Karras NA, Brown PA, Qayed M, Hermiston ML, Satwani P, Krupski C, Keating AK, Wilcox R, Rabik CA, Fabrizio VA, Kunicki M, Chinnabhandar V, Goksenin AY, Curran KJ, Mackall CL, Laetsch TW, Schultz LM. Out of Specification Tisagenlecleucel Does Not Compromise Safety or Efficacy in Pediatric Acute Lymphoblastic Leukemia. Blood. 2021 Sep 09.  View on PubMed
  9. Michael W. Boyer, Sonali Chaudhury, Kara L. Davis, Timothy Alan Driscoll, Stephan A. Grupp, Michelle Hermiston, Samuel John, Amy K. Keating, Christina Kovacs, G. Doug Myers, Christine L. Phillips, Michael A. Pulsipher, Julie-An Talano, Gabor Kari, Jennifer Willert. ALL-026: Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion Following Loss of B-Cell Aplasia in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia: HESTER Phase II Study. Clinical Lymphoma Myeloma & Leukemia. 2021 Sep 1; 21:s262-s263.  View on PubMed
  10. Michael W. Boyer, Sonali Chaudhury, Kara L. Davis, Timothy Alan Driscoll, Stephan A. Grupp, Michelle Hermiston, Samuel John, Amy K. Keating, Christina Kovacs, G. Doug Myers, Christine L. Phillips, Michael A. Pulsipher, Julie-An Talano, Gabor Kari, Jennifer Willert. Poster: ALL-026: Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion Following Loss of B-Cell Aplasia in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia: HESTER Phase II Study. Clinical Lymphoma Myeloma & Leukemia. 2021 Sep 1; 21:s209.  View on PubMed
  11. Nguyen MC, Nguyen V, Le H, Nguyen DV, Nguyen ML, Hermiston ML, Bui CB, Loh AHP. Subcutaneous panniculitis-like T-cell lymphomas with homozygous inheritance of HAVCR2 mutations in Vietnamese pedigrees. Pediatr Blood Cancer. 2021 Aug 16; e29292.  View on PubMed
  12. Smith GA, Levinson AL, Galvin RT, Lalor LE, McCalmont T, Wang L, Geis MC, Odegaard K, Hupp M, Maguiness S, Turcotte LM, Cordoro KM, Hermiston ML. Concurrent Subcutaneous Panniculitis-like T-Cell Lymphoma and B-Cell Acute Lymphoblastic Leukemia in 2 Pediatric Patients. J Pediatr Hematol Oncol. 2021 08 01; 43(6):e791-e794.  View on PubMed
  13. Lauren K. Meyer, Ritu Roy, Benjamin J. Huang, Cristina Delgado-Martin, Tiffaney L. Vincent, Brent L. Wood, Yu Liu, Jinghui Zhang, Charles Grenfell Mullighan, Terzah M. Horton, Mignon L. Loh, Meenakshi Devidas, Elizabeth A. Raetz, Robert J. Hayashi, Stuart S. Winter, Kimberly P. Dunsmore, Stephen Hunger, David T. Teachey, Adam B. Olshen, Michelle L. Hermiston. Targeted gene expression classifier identifies pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients at high risk for end induction minimal residual disease positivity. Journal of Clinical Oncology. 2021 May 20; 39(15_suppl):10002-10002.  View on PubMed
  14. K.J. Curran, V.A. Fabrizio, A. Mauguen, J.J. Boelens, C. Baggott, S. Prabhu, H. Placenta, C.L. Phillips, J. Rossoff, H. Stefanski, J. Talano, A. Moskop, S.P. Margossian, M.R. Verneris, G. Myers, N.A. Karras, P.A. Brown, M. Qayed, M. Hermiston, P. Satwani, C. Krupski, A. Keating, R. Wilcox, C.A. Rabik, V. Chinnabhandar, M. Kunicki, A. Goksenin, C. Mackall, T.W. Laetsch, L.M. Schultz. Fludarabine-exposure predicts disease control following CD19-specific car t cell (tisagenlecleucel); a report from pediatric real-world car consortium. Cytotherapy. 2021 May 1; 23(5):s27.  View on PubMed
  15. Chaturvedi V, Marsh RA, Zoref-Lorenz A, Owsley E, Chaturvedi V, Nguyen TC, Goldman JR, Henry MM, Greenberg JN, Ladisch S, Hermiston ML, Jeng M, Naqvi A, Allen CE, Wong HR, Jordan MB. T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis. Blood. 2021 Apr 29; 137(17):2337-2346.  View on PubMed
  16. Hermiston ML. Double trouble for Langerhans cell histiocytosis. Blood. 2021 04 01; 137(13):1705-1706.  View on PubMed
  17. Michael W Boyer, Sonali Chaudhury, Kara L Davis, Timothy Alan Driscoll, Stephan Grupp, Michelle Hermiston, Samuel John, Amy K Keating, Christina Kovacs, Andrea Magley, G. Doug Myers, Christine L Phillips, Mike A. Pulsipher, Das Purkayastha, Julie-An Talano, Olufolake A Adisa, Jennifer Willert. 149 Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion Following Loss of B-Cell Aplasia in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia: HESTER Phase II Study. . 2021 Mar 1; 27(3):s141-s142.  View on PubMed
  18. David T. Teachey, Meenakshi Devidas, Brent L Wood, Zhiguo Chen, Robert James Hayashi, Robert D Annett, Barbara L Asselin, Keith J August, Steve Y Cho, Kimberly P. Dunsmore, Brian T. Fisher, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Michelle L. Hermiston, Terzah M Horton, Alok I Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I Patel, Eric S. Schafer, Tal Schechter-Finkelstein, Kristin A. Shimano, Neelam Singh, Amii C. Steele, Maria L. Sulis, Sarah L Vargas, Stuart S. Winter, Charlotte Wood, Patrick Zweider McKay, Catherine M. Bollard, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz. Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231. Blood. 2020 Nov 5; 136(Supplement 1):11-12.  View on PubMed
  19. Michael W Boyer, Sonali Chaudhury, Kara L Davis, Timothy Alan Driscoll, Stephan A Grupp, Michelle Hermiston, Samuel John, Amy K Keating, Christina Kovacs, Andrea Magley, Gary Douglas Myers, Christine L Phillips, Michael A Pulsipher, Das Purkayastha, Julie-An Talano, Jennifer Willert. HESTER: A Phase II Study Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia Experiencing Loss of B-Cell Aplasia. Blood. 2020 Nov 5; 136(Supplement 1):23-24.  View on PubMed
  20. Alan S. Wayne, Gerard Michel, Daniel W. Lee, André Baruchel, Sonali Chaudhury, Patrick A. Brown, Michelle Hermiston, Joerg Krueger, Tong Shen, Kristy Tailford, Behzad Kharabi Masouleh. ZUMA-4: A Phase 1/2 Multicenter Study of KTE-X19 in Pediatric and Adolescent Patients With Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma. Blood. 2020 Nov 5; 136(Supplement 1):42-42.  View on PubMed

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