Research Summary

Steven Hetts, MD, is an Associate Professor of Radiology in Residence at the University of California, San Francisco, and he is Chief of Neuroradiology at the San Francisco General Hospital where he has established a new clinical Interventional Neuroradiology service, providing cutting edge minimally invasive endovascular therapy. Dr. Hetts received his medical degree from Harvard Medical School in Boston, Massachusetts in 2000, and completed a residency in Diagnostic Radiology at UCSF, followed by a fellowship in Diagnostic Neuroradiology and Interventional Neuroradiology from UCSF.

Dr. Hetts is involved in translational research as Co-Director of the Interventional Radiology Laboratory at China Basin, including the conception, performance, and management of research projects translating basic science and engineering research into clinical applicability. One of his projects is Magnetic Catheter Navigation and Microinfarction Evaluation in the Brain and Heart. Dr. Hetts also implements many clinical research projects involving retrospective and prospective patient data. The main focus of his clinical research is endovascular therapy for cerebrovascular disease, spinal vascular disease, and neurooncology.

Research Funding

  • June 1, 2015 - May 31, 2020 - Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce Toxicity, Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R01CA194533
  • February 1, 2016 - January 31, 2018 - Improved sensitivity and safety for endovascular MR imaging at 3T, Co-Principal Investigator. Sponsor: NIH/NIBIB, Sponsor Award ID: R21EB020283
  • August 1, 2011 - May 31, 2015 - Endovascular Interventional MRI: Optimizing Tools and Techniques at 3T, Principal Investigator. Sponsor: NIH/NIBIB, Sponsor Award ID: R01EB012031
  • June 1, 2015 - May 31, 2020 - Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce Toxicity, Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R01CA194533

Education

Harvard College, Boston, MA, AB summa cum laude, 06/1996, Biology
Harvard Medical School, Boston, MA, MD, 06/2000, Medicine
Stanford University Medical Center, Stanford, CA, Internship, 06/2001, Internal Medicine
UCSF Medical Center, San Francisco, CA, Residency, 06/2005, Diagnostic Radiology
UCSF Medical Center, San Francisco, CA, Fellowship, 06/2006, Diagnostic Neuroradiology
UCSF Medical Center, San Francisco, CA, Fellowship, 02/2008, Interventional Neuroradiology

Honors & Awards

  • 1992
    United States Presidential Scholar, highest academic honor for US high school students
  • 1993-1996
    John Harvard Scholarship and Dean’s List, Harvard College
  • 1995
    Phi Beta Kappa, elected in Senior 45, Harvard College
  • 1996
    Biology Undergraduate Honors Thesis, summa cum laude
  • 1997
    Finalist, Rhodes Scholarship, California Nominee to Region VIII Competition
  • 1999
    Aesculapian Club, Harvard Medical School
  • 2001
    Nominee, Resident Teaching Award, Department of Internal Medicine, Stanford Hospital
  • 2002, 2003
    Margulis Society Radiology Resident Research Award
  • 2003
    American Roentgen Ray Society Introduction to Research Program
  • 2004
    International Society for Magnetic Resonance in Medicine Amersham Fellowship
  • 2004
    American Society of Pediatric Neuroradiology Annual Research Award
  • 2005
    Executive Council Award, Residents in Radiology Competition, American Roentgen Ray Society
  • 2010, 2011
    American Society of Neuroradiology, Neuroradiology Research and Education Foundation Scholar Award in Neuroradiology Research
  • 2012
    Visiting Professor, Memorial Sloan Kettering Cancer Center
  • 2015
    Nominee, QB3 Award for Startup of the Year, ChemoFilter
  • 2015
    Fellow, Rosenman Institute, UCSF

Selected Publications

  1. Garcia JH, Morshed RA, Winkler EA, Li Y, Fox CK, Fullerton HJ, Rutledge C, Beniwal AS, Lawton MT, Abla AA, Gupta N, Hetts SW. Pediatric moyamoya MRI score: an imaging-based scale to predict outcomes in surgically treated pediatric patients with moyamoya. Neurosurg Focus. 2021 09; 51(3):E8.  View on PubMed
  2. Narsinh KH, Paez R, Mueller K, Caton MT, Baker A, Higashida RT, Halbach VV, Dowd CF, Amans MR, Hetts SW, Norbash AM, Cooke DL. Robotics for neuroendovascular intervention: Background and primer. Neuroradiol J. 2021 Aug 16; 19714009211034829.  View on PubMed
  3. Yue JK, Chang D, Oh T, Winkler EA, Lu AY, Hetts SW, Young EP, Reddy AT, Fox CK, Abla AA, Roland JL. Multiple Tumor-Associated Intracranial Aneurysms Adjacent to a Suprasellar Germ Cell Tumor: Case Report and Review of Literature. Pediatr Neurosurg. 2021; 56(5):482-491.  View on PubMed
  4. Eisenmenger LB, Junn JC, Cooke D, Hetts S, Zhu C, Johnson KM, Manunga JM, Saloner D, Hess C, Kim H. Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall "Enhancement". Front Neurosci. 2021; 15:697432.  View on PubMed
  5. Mekonnen ZK, Everett LA, Hetts SW, Afshar AR. Retinal emboli after cervicopetrous junction internal carotid artery pseudoaneurysm stenting. Am J Ophthalmol Case Rep. 2021 Sep; 23:101164.  View on PubMed
  6. Al-Mufti F, Schirmer CM, Starke RM, Chaudhary N, De Leacy R, Tjoumakaris SI, Haranhalli N, Abecassis IJ, Amuluru K, Bulsara KR, Hetts SW, SNIS Standards and Guidelines Committee and SNIS Board of Directors . Thrombectomy in special populations: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee. J Neurointerv Surg. 2021 Jul 08.  View on PubMed
  7. Gao S, Nelson J, Weinsheimer S, Winkler EA, Rutledge C, Abla AA, Gupta N, Shieh JT, Cooke DL, Hetts SW, Tihan T, Hess CP, Ko N, Walcott BP, McCulloch CE, Lawton MT, Su H, Pawlikowska L, Kim H. Somatic mosaicism in the MAPK pathway in sporadic brain arteriovenous malformation and association with phenotype. J Neurosurg. 2021 Jul 02; 1-8.  View on PubMed
  8. Faughnan ME, Mager JJ, Hetts SW, Palda VA, Ratjen F. Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia. Ann Intern Med. 2021 07; 174(7):1035-1036.  View on PubMed
  9. Hanel RA, Yoon N, Sauvageau E, Aghaebrahim A, Lin E, Jadhav AP, Jovin TG, Khaldi A, Gupta RG, Johnson A, Frei D, Loy D, Malek A, Toth G, Siddiqui A, Reavey-Cantwell J, Thomas A, Hetts SW, Jankowitz BT, Zaidat OO. Neuroform Atlas Stent for Treatment of Middle Cerebral Artery Aneurysms: 1-Year Outcomes From Neuroform Atlas Stent Pivotal Trial. Neurosurgery. 2021 06 15; 89(1):102-108.  View on PubMed
  10. Yee DW, Hetts SW, Greer JR. 3D-Printed Drug Capture Materials Based on Genomic DNA Coatings. ACS Appl Mater Interfaces. 2021 Sep 08; 13(35):41424-41434.  View on PubMed
  11. Caton MT, Narsinh KH, Baker A, Hetts SW, Cooke DL, Higashida RT, Dowd CF, Halbach VV, Amans MR. Endovascular treatment strategy, technique, and outcomes for dural arteriovenous fistulas of the marginal sinus region. J Neurointerv Surg. 2021 May 26.  View on PubMed
  12. Amans MR, Smith E, Narsinh KH, Dowd CF, Higashida RT, Halbach VV, Hetts SW, Cooke DL, Nelson J, Mccoy D, Ciano M, Dillon WP, Copelan AZ, Drocton GT, Khangura RS, Murph D, Hartley ZJ, Abla AA. Reply. AJNR Am J Neuroradiol. 2021 08; 42(8):E58-E59.  View on PubMed
  13. Hetts SW, Shieh JT, Ohliger MA, Conrad MB. Hereditary Hemorrhagic Telangiectasia: The Convergence of Genotype, Phenotype, and Imaging in Modern Diagnosis and Management of a Multisystem Disease. Radiology. 2021 07; 300(1):17-30.  View on PubMed
  14. Caton MT, Narsinh KH, Baker A, Dowd CF, Higashida RT, Cooke DL, Hetts SW, Halbach VV, Amans MR. Dural Arteriovenous Fistulas of the Foramen Magnum Region: Clinical Features and Angioarchitectural Phenotypes. AJNR Am J Neuroradiol. 2021 08; 42(8):1486-1491.  View on PubMed
  15. Chaudhary N, Elijovich L, Martinez M, Fifi JT, Ortega-Gutierrez S, Shaibani A, Pandey AS, Suzuki S, Field RR, Gemmete JJ, Cooke DL, Narayanan S, Hetts SW, Orbach DB, Pearl MS. Pediatric diagnostic cerebral angiography: practice recommendations from the SNIS Pediatric Committee. J Neurointerv Surg. 2021 Aug; 13(8):762-766.  View on PubMed
  16. Caton MT, Copelan AZ, Narsinh KH, Baker A, Abla AA, Higashida RT, Amans MR, Hetts SW, Cooke DL. The Geometry of Y-Stent Configurations Used for Wide-Necked Aneurysm Treatment: Analyzing Double-Barrel Stents In Vitro Using Flat-Panel Computed Tomography. World Neurosurg. 2021 07; 151:e363-e371.  View on PubMed
  17. Nogueira RG, Abdalkader M, Qureshi MM, Frankel MR, Mansour OY, Yamagami H, Qiu Z, Farhoudi M, Siegler JE, Yaghi S, Raz E, Sakai N, Ohara N, Piotin M, Mechtouff L, Eker O, Chalumeau V, Kleinig TJ, Pop R, Liu J, Winters HS, Shang X, Vasquez AR, Blasco J, Arenillas JF, Martinez-Galdamez M, Brehm A, Psychogios MN, Lylyk P, Haussen DC, Al-Bayati AR, Mohammaden MH, Fonseca L, Luís Silva M, Montalverne F, Renieri L, Mangiafico S, Fischer U, Gralla J, Frei D, Chugh C, Mehta BP, Nagel S, Mohlenbruch M, Ortega-Gutierrez S, Farooqui M, Hassan AE, Taylor A, Lapergue B, Consoli A, Campbell BC, Sharma M, Walker M, Van Horn N, Fiehler J, Nguyen HT, Nguyen QT, Watanabe D, Zhang H, Le HV, Nguyen VQ, Shah R, Devlin T, Khandelwal P, Linfante I, Izzath W, Lavados PM, Olavarría VV, Sampaio Silva G, de Carvalho Sousa AV, Kirmani J, Bendszus M, Amano T, Yamamoto R, Doijiri R, Tokuda N, Yamada T, Terasaki T, Yazawa Y, Morris JG, Griffin E, Thornton J, Lavoie P, Matouk C, Hill MD, Demchuk AM, Killer-Oberpfalzer M, Nahab F, Altschul D, Ramos-Pachón A, Pérez de la Ossa N, Kikano R, Boisseau W, Walker G, Cordina SM, Puri A, Luisa Kuhn A, Gandhi D, Ramakrishnan P, Novakovic-White R, Chebl A, Kargiotis O, Czap A, Zha A, Masoud HE, Lopez C, Ozretic D, Al-Mufti F, Zie W, Duan Z, Yuan Z, Huang W, Hao Y, Luo J, Kalousek V, Bourcier R, Guile R, Hetts S, Al-Jehani HM, AlHazzani A, Sadeghi-Hokmabadi E, Teleb M, Payne J, Lee JS, Hong JM, Sohn SI, Hwang YH, Shin DH, Roh HG, Edgell R, Khatri R, Smith A, Malik A, Liebeskind D, Herial N, Jabbour P, Magalhaes P, Ozdemir AO, Aykac O, Uwatoko T, Dembo T, Shimizu H, Sugiura Y, Miyashita F, Fukuda H, Miyake K, Shimbo J, Sugimura Y, Beer-Furlan A, Joshi K, Catanese L, Abud DG, Neto OG, Mehrpour M, Al Hashmi A, Saqqur M, Mostafa A, Fifi JT, Hussain S, John S, Gupta R, Sivan-Hoffmann R, Reznik A, Sani AF, Geyik S, Akil E, Churojana A, Ghoreishi A, Saadatnia M, Sharifipour E, Ma A, Faulder K, Wu T, Leung L, Malek A, Voetsch B, Wakhloo A, Rivera R, Barrientos Iman DM, Pikula A, Lioutas VA, Thomalla G, Birnbaum L, Machi P, Bernava G, McDermott M, Kleindorfer D, Wong K, Patterson MS, Fiorot JA, Huded V, Mack W, Tenser M, Eskey C, Multani S, Kelly M, Janardhan V, Cornett O, Singh V, Murayama Y, Mokin M, Yang P, Zhang X, Yin C, Han H, Peng Y, Chen W, Crosa R, Frudit ME, Pandian JD, Kulkarni A, Yagita Y, Takenobu Y, Matsumaru Y, Yamada S, Kono R, Kanamaru T, Yamazaki H, Sakaguchi M, Todo K, Yamamoto N, Sonoda K, Yoshida T, Hashimoto H, Nakahara I, Cora E, Volders D, Ducroux C, Shoamanesh A, Ospel J, Kaliaev A, Ahmed S, Rashid U, Rebello LC, Pereira VM, Fahed R, Chen M, Sheth SA, Palaiodimou L, Tsivgoulis G, Chandra R, Koyfman F, Leung T, Khosravani H, Dharmadhikari S, Frisullo G, Calabresi P, Tsiskaridze A, Lobjanidze N, Grigoryan M, Czlonkowska A, de Sousa DA, Demeestere J, Liang C, Sangha N, Lutsep HL, Ayo-Martín Ó, Cruz-Culebras A, Tran AD, Young CY, Cordonnier C, Caparros F, De Lecinana MA, Fuentes B, Yavagal D, Jovin T, Spelle L, Moret J, Khatri P, Zaidat O, Raymond J, Martins S, Nguyen T. Global impact of COVID-19 on stroke care. Int J Stroke. 2021 07; 16(5):573-584.  View on PubMed
  18. Nguyen TN, Haussen DC, Qureshi MM, Yamagami H, Fujinaka T, Mansour OY, Abdalkader M, Frankel M, Qiu Z, Taylor A, Lylyk P, Eker OF, Mechtouff L, Piotin M, Lima FO, Mont'Alverne F, Izzath W, Sakai N, Mohammaden M, Al-Bayati AR, Renieri L, Mangiafico S, Ozretic D, Chalumeau V, Ahmad S, Rashid U, Hussain SI, John S, Griffin E, Thornton J, Fiorot JA, Rivera R, Hammami N, Cervantes-Arslanian AM, Dasenbrock HH, Vu HL, Nguyen VQ, Hetts S, Bourcier R, Guile R, Walker M, Sharma M, Frei D, Jabbour P, Herial N, Al-Mufti F, Ozdemir AO, Aykac O, Gandhi D, Chugh C, Matouk C, Lavoie P, Edgell R, Beer-Furlan A, Chen M, Killer-Oberpfalzer M, Pereira VM, Nicholson P, Huded V, Ohara N, Watanabe D, Shin DH, Magalhaes PS, Kikano R, Ortega-Gutierrez S, Farooqui M, Abou-Hamden A, Amano T, Yamamoto R, Weeks A, Cora EA, Sivan-Hoffmann R, Crosa R, Möhlenbruch M, Nagel S, Al-Jehani H, Sheth SA, Lopez Rivera VS, Siegler JE, Sani AF, Puri AS, Kuhn AL, Bernava G, Machi P, Abud DG, Pontes-Neto OM, Wakhloo AK, Voetsch B, Raz E, Yaghi S, Mehta BP, Kimura N, Murakami M, Lee JS, Hong JM, Fahed R, Walker G, Hagashi E, Cordina SM, Roh HG, Wong K, Arenillas JF, Martinez-Galdamez M, Blasco J, Rodriguez Vasquez A, Fonseca L, Silva ML, Wu TY, John S, Brehm A, Psychogios M, Mack WJ, Tenser M, Todaka T, Fujimura M, Novakovic R, Deguchi J, Sugiura Y, Tokimura H, Khatri R, Kelly M, Peeling L, Murayama Y, Winters HS, Wong J, Teleb M, Payne J, Fukuda H, Miyake K, Shimbo J, Sugimura Y, Uno M, Takenobu Y, Matsumaru Y, Yamada S, Kono R, Kanamaru T, Morimoto M, Iida J, Saini V, Yavagal D, Bushnaq S, Huang W, Linfante I, Kirmani J, Liebeskind DS, Szeder V, Shah R, Devlin TG, Birnbaum L, Luo J, Churojana A, Masoud HE, Lopez CY, Steinfort B, Ma A, Hassan AE, Al Hashmi A, McDermott M, Mokin M, Chebl A, Kargiotis O, Tsivgoulis G, Morris JG, Eskey CJ, Thon J, Rebello L, Altschul D, Cornett O, Singh V, Pandian J, Kulkarni A, Lavados PM, Olavarria VV, Todo K, Yamamoto Y, Silva GS, Geyik S, Johann J, Multani S, Kaliaev A, Sonoda K, Hashimoto H, Alhazzani A, Chung DY, Mayer SA, Fifi JT, Hill MD, Zhang H, Yuan Z, Shang X, Castonguay AC, Gupta R, Jovin TG, Raymond J, Zaidat OO, Nogueira RG, SVIN COVID-19 Registry, the Middle East North Africa Stroke and Interventional Neurotherapies Organi , Japanese Society of Vascular and Interventional Neurology Society (JVIN) . Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID-19 pandemic. Stroke Vasc Neurol. 2021 Mar 26.  View on PubMed
  19. Jankowitz BT, Jadhav AP, Gross B, Jovin TG, Alhajeri AA, Fraser JF, Hanel RA, Sauvageau E, Aghaebrahim A, Frei D, Bellon R, Loy D, Puri AS, Malek AM, Thomas A, Toth G, Lopes DK, Crowley RW, Arthur AS, Reavey-Cantwell J, Lin E, Siddiqui AH, Alexander MJ, Khaldi A, Colby GP, Caplan JM, Satti SR, Turk AS, Spiotta AM, Klucznik R, Hallam DK, Kung D, Froehler MT, Callison RC, Kan P, Hetts SW, Zaidat OO. Pivotal trial of the Neuroform Atlas stent for treatment of posterior circulation aneurysms: one-year outcomes. J Neurointerv Surg. 2021 Mar 15.  View on PubMed
  20. Fargen KM, Lee SK, Mokin M, Kayan Y, De Leacy R, Al-Mufti F, Ansari SA, Haranhalli N, Prestigiacomo CJ, Schirmer CM, Fraser JF, Hetts SW, SNIS Standards and Guidelines Committee , SNIS Board of Directors . Social media usage for neurointerventionalists: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee. J Neurointerv Surg. 2021 Jul; 13(7):674-678.  View on PubMed

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