Research Summary

Steven Hetts, MD, is an Associate Professor of Radiology in Residence at the University of California, San Francisco, and he is Chief of Neuroradiology at the San Francisco General Hospital where he has established a new clinical Interventional Neuroradiology service, providing cutting edge minimally invasive endovascular therapy. Dr. Hetts received his medical degree from Harvard Medical School in Boston, Massachusetts in 2000, and completed a residency in Diagnostic Radiology at UCSF, followed by a fellowship in Diagnostic Neuroradiology and Interventional Neuroradiology from UCSF.

Dr. Hetts is involved in translational research as Co-Director of the Interventional Radiology Laboratory at China Basin, including the conception, performance, and management of research projects translating basic science and engineering research into clinical applicability. One of his projects is Magnetic Catheter Navigation and Microinfarction Evaluation in the Brain and Heart. Dr. Hetts also implements many clinical research projects involving retrospective and prospective patient data. The main focus of his clinical research is endovascular therapy for cerebrovascular disease, spinal vascular disease, and neurooncology.

Research Funding

  • September 23, 2021 - June 30, 2022 - Endovascular ChemoFilter to Reduce Doxorubicin Toxicity during Intra-Arterial Chemotherapy , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R42CA265316
  • August 1, 2011 - March 31, 2022 - Endovascular Interventional MRI: Optimizing Tools and Techniques at 3T , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01EB012031
  • June 1, 2015 - May 31, 2021 - Endovascular Chemofiltration: Optimizing Removal of Chemotherapeutics and Nanoparticles from the Blood to Reduce Toxicity , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01CA194533
  • February 1, 2016 - January 31, 2019 - Improved sensitivity and safety for endovascular MR imaging at 3T , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21EB020283

Education

Harvard College, Boston, MA, AB summa cum laude, 06/1996, Biology
Harvard Medical School, Boston, MA, MD, 06/2000, Medicine
Stanford University Medical Center, Stanford, CA, Internship, 06/2001, Internal Medicine
UCSF Medical Center, San Francisco, CA, Residency, 06/2005, Diagnostic Radiology
UCSF Medical Center, San Francisco, CA, Fellowship, 06/2006, Diagnostic Neuroradiology
UCSF Medical Center, San Francisco, CA, Fellowship, 02/2008, Interventional Neuroradiology

Honors & Awards

  • 1992
    United States Presidential Scholar, highest academic honor for US high school students
  • 1993-1996
    John Harvard Scholarship and Dean’s List, Harvard College
  • 1995
    Phi Beta Kappa, elected in Senior 45, Harvard College
  • 1996
    Biology Undergraduate Honors Thesis, summa cum laude
  • 1997
    Finalist, Rhodes Scholarship, California Nominee to Region VIII Competition
  • 1999
    Aesculapian Club, Harvard Medical School
  • 2001
    Nominee, Resident Teaching Award, Department of Internal Medicine, Stanford Hospital
  • 2002, 2003
    Margulis Society Radiology Resident Research Award
  • 2003
    American Roentgen Ray Society Introduction to Research Program
  • 2004
    International Society for Magnetic Resonance in Medicine Amersham Fellowship
  • 2004
    American Society of Pediatric Neuroradiology Annual Research Award
  • 2005
    Executive Council Award, Residents in Radiology Competition, American Roentgen Ray Society
  • 2010, 2011
    American Society of Neuroradiology, Neuroradiology Research and Education Foundation Scholar Award in Neuroradiology Research
  • 2012
    Visiting Professor, Memorial Sloan Kettering Cancer Center
  • 2015
    Nominee, QB3 Award for Startup of the Year, ChemoFilter
  • 2015
    Fellow, Rosenman Institute, UCSF

Selected Publications

  1. Baker A, Hemphill K, Smith ER, Cooke DL, Hetts SW, Amans MR, Higashida RT, Narsinh KH. Transvenous coil embolization of a Cognard V transverse-sigmoid sinus dural arteriovenous fistula. Interv Neuroradiol. 2023 Aug 08; 15910199231188257.  View on PubMed
  2. Cooke DL, Shen H, Duvvuri M, Thompson D, Neylan T, Wolfe W, Hetts S, Ovbiagele B, Whooley M, Cohen B. Association of select psychiatric disorders with incident brain aneurysm and subarachnoid hemorrhage among veterans. Front Integr Neurosci. 2023; 17:1207610.  View on PubMed
  3. Hetts SW, Al-Mufti F, Dabus G, Fifi JT, Mocco J, Jayaraman MV. Focused update to guidelines for endovascular therapy for emergent large vessel occlusion: large core and basilar artery occlusion patients. J Neurointerv Surg. 2023 Jul 21.  View on PubMed
  4. Garcia JH, Carrete L, Rutledge WC, Raygor KP, Winkler EA, Pereira MP, Nelson J, Kim H, Cooke DL, Hetts SW, Lawton MT, Abla AA. Factors Associated with Unfavorable Clinical Presentations in Patients with Ruptured BrainArteriovenous Malformations. World Neurosurg. 2023 Jul 06.  View on PubMed
  5. Hoh BL, Ko NU, Amin-Hanjani S, Chou SH-Y, Cruz-Flores S, Dangayach NS, Derdeyn CP, Du R, Hänggi D, Hetts SW, Ifejika NL, Johnson R, Keigher KM, Leslie-Mazwi TM, Lucke-Wold B, Rabinstein AA, Robicsek SA, Stapleton CJ, Suarez JI, Tjoumakaris SI, Welch BG. 2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2023 07; 54(7):e314-e370.  View on PubMed
  6. Schirmer CM, Bulsara KR, Al-Mufti F, Haranhalli N, Thibault L, Hetts SW, SNIS Standards and Guidelines Committee. Antiplatelets and antithrombotics in neurointerventional procedures: Guideline update. J Neurointerv Surg. 2023 May 15.  View on PubMed
  7. Yusuf HM, Rasheed A, Hetts S, Kim H, Loftus P, Conrad M. Exploring effects of atmospheric conditions in hereditary hemorrhagic telangiectasia. Int Forum Allergy Rhinol. 2023 May 15.  View on PubMed
  8. Reynolds CD, Caton MT, Baker A, Smith ER, Amans MR, Cooke DL, Dowd CF, Higashida RT, Gupta N, Abla AA, Auguste K, Fox CH, Fullerton H, Hetts SW. Clarifying the clinical landscape of pediatric spinal arteriovenous shunts: an institutional experience and individual patient-data meta-analysis. J Neurointerv Surg. 2023 Mar 15.  View on PubMed
  9. Lu AY, Winkler EA, Garcia JH, Raygor KP, Fullerton HJ, Fox CK, Kim H, Auguste KI, Sun PP, Hetts SW, Lawton MT, Abla AA, Gupta N. A comparison of incidental and symptomatic unruptured brain arteriovenous malformations in children. J Neurosurg Pediatr. 2023 05 01; 31(5):463-468.  View on PubMed
  10. Baker A, Caton MT, Smith ER, Narsinh KH, Amans MR, Higashida RT, Cooke DL, Dowd CF, Hetts SW. Evolving indications for pediatric neurointerventional radiology: A single institutional 25-year experience in infants less than one year of age and a brief historical review. Interv Neuroradiol. 2023 Feb 09; 15910199231154689.  View on PubMed
  11. Caton MT, Duvvuri M, Baker A, Smith ER, Narsinh KH, Amans MR, Hetts SW, Higashida RT, Cooke DL, Dowd CF. Percutaneous sclerotherapy for head and neck lymphatic malformations in neonates and infants ≤12 months of age. J Neurointerv Surg. 2022 Nov 22.  View on PubMed
  12. Baker A, Narayanan S, Tsai JP, Tjoumakaris SI, Haranhalli N, Fraser JF, Hetts SW, SNIS Standards and Guidelines Committee, SNIS Board of Directors. Society of NeuroInterventional Surgery: position statement on pregnancy and parental leave for physicians practicing neurointerventional surgery. J Neurointerv Surg. 2022 Nov 17.  View on PubMed
  13. Kilbride BF, Narsinh KH, Jordan CD, Mueller K, Moore T, Martin AJ, Wilson MW, Hetts SW. MRI-guided endovascular intervention: current methods and future potential. Expert Rev Med Devices. 2022 Oct; 19(10):763-778.  View on PubMed
  14. Yusuf H, Rasheed A, Kim H, Conrad MB, Hetts SW. Identifying racial disparities in hereditary hemorrhagic telangiectasia. J Neurointerv Surg. 2023 Oct; 15(10):1050-1054.  View on PubMed
  15. Karandikar A, Solberg A, Fung A, Lee AY, Farooq A, Taylor AC, Oliveira A, Narayan A, Senter A, Majid A, Tong A, McGrath AL, Malik A, Brown AL, Roberts A, Fleischer A, Vettiyil B, Zigmund B, Park B, Curran B, Henry C, Jaimes C, Connolly C, Robson C, Meltzer CC, Phillips CH, Dove C, Glastonbury C, Pomeranz C, Kirsch CFE, Burgan CM, Scher C, Tomblinson C, Fuss C, Santillan C, Daye D, Brown DB, Young DJ, Kopans D, Vargas D, Martin D, Thompson D, Jordan DW, Shatzkes D, Sun D, Mastrodicasa D, Smith E, Korngold E, Dibble EH, Arleo EK, Hecht EM, Morris E, Maltin EP, Cooke EA, Schwartz ES, Lehrman E, Sodagari F, Shah F, Doo FX, Rigiroli F, Vilanilam GK, Landinez G, Kim GG, Rahbar H, Choi H, Bandesha H, Ojeda-Fournier H, Ikuta I, Dragojevic I, Schroeder JLT, Ivanidze J, Katzen JT, Chiang J, Nguyen J, Robinson JD, Broder JC, Kemp J, Weaver JS, Conyers JM, Robbins JB, Leschied JR, Wen J, Park J, Mongan J, Perchik J, Barbero JPM, Jacob J, Ledbetter K, Macura KJ, Maturen KE, Frederick-Dyer K, Dodelzon K, Cort K, Kisling K, Babagbemi K, McGill KC, Chang KJ, Feigin K, Winsor KS, Seifert K, Patel K, Porter KK, Foley KM, Patel-Lippmann K, McIntosh LJ, Padilla L, Groner L, Harry LM, Ladd LM, Wang L, Spalluto LB, Mahesh M, Marx MV, Sugi MD, Sammer MBK, Sun M, Barkovich MJ, Miller MJ, Vella M, Davis MA, Englander MJ, Durst M, Oumano M, Wood MJ, McBee MP, Fischbein NJ, Kovalchuk N, Lall N, Eclov N, Madhuripan N, Ariaratnam NS, Vincoff NS, Kothary N, Yahyavi-Firouz-Abadi N, Brook OR, Glenn OA, Woodard PK, Mazaheri P, Rhyner P, Eby PR, Raghu P, Gerson RF, Patel R, Gutierrez RL, Gebhard R, Andreotti RF, Masum R, Woods R, Mandava S, Harrington SG, Parikh S, Chu S, Arora SS, Meyers SM, Prabhu S, Shams S, Pittman S, Patel SN, Payne S, Hetts SW, Hijaz TA, Chapman T, Loehfelm TW, Juang T, Clark TJ, Potigailo V, Shah V, Planz V, Kalia V, DeMartini W, Dillon WP, Gupta Y, Koethe Y, Hartley-Blossom Z, Wang ZJ, McGinty G, Haramati A, Allen LM, Germaine P. Radiologists staunchly support patient safety and autonomy, in opposition to the SCOTUS decision to overturn Roe v Wade. Clin Imaging. 2023 01; 93:117-121.  View on PubMed
  16. Abruzzo T, van den Berg R, Vadivelu S, Hetts SW, Dishop M, Cornejo P, Narayanan V, Ramsey KE, Coopwood C, Medici-van den Herik EG, Roosendaal SD, Lawton M, Bernes S. Arterioectatic Spinal Angiopathy of Childhood: Clinical, Imaging, Laboratory, Histologic, and Genetic Description of a Novel CNS Vascular Pathology. AJNR Am J Neuroradiol. 2022 07; 43(7):1060-1067.  View on PubMed
  17. Saggi S, Winkler EA, Ammanuel SG, Morshed RA, Garcia JH, Young JS, Semonche A, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Abla A, Lawton MT, Gupta N. Machine learning for predicting hemorrhage in pediatric patients with brain arteriovenous malformation. J Neurosurg Pediatr. 2022 08 01; 30(2):203-209.  View on PubMed
  18. Baker A, Raygor K, Caton MT, Narsinh KH, Smith E, Dowd CF, Cooke DL, Higashida RT, Amans MR, Abla AA, Hetts SW. Pharyngo-tympano-stapedial middle meningeal artery variant supply to a falcotentorial dural arteriovenous fistula. J Neurointerv Surg. 2022 May 11.  View on PubMed
  19. Yue JK, Chang D, Caton MT, Haddad AF, Dalle Ore CL, Wozny TA, Oh T, Wang AS, Tonetti DA, Auguste KI, Sun PP, Cooke DL, Hetts SW, Abla AA, Gupta N, Roland JL. The Hybrid Operative Suite with Intraoperative Biplane Rotational Angiography in Pediatric Cerebrovascular Neurosurgery: Utility and Lessons Learned. Pediatr Neurosurg. 2022; 57(4):245-259.  View on PubMed
  20. Caton MT, Mark IT, Narsinh KH, Baker A, Cooke DL, Hetts SW, Dowd CF, Halbach VV, Higashida RT, Ko NU, Chung SA, Amans MR. Endovascular Therapy for Intracranial Giant Cell Arteritis : Systematic Review, Technical Considerations and the Effect of Intra-arterial Calcium Channel Blockers. Clin Neuroradiol. 2022 May 03.  View on PubMed

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