Research Summary

Dr. Chiung-Yu Huang is a Professor of Biostatistics at the Department of Epidemiology and Biostatistics at the University of California, San Francisco (UCSF) and serves as an Adjunct Professor at the Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center. Dr. Huang is a Fellow of the American Statistical Association (ASA) and is well known for her contributions to methodology research, particularly in the areas of survival analysis, competing risks analysis, recurrent event analysis, outcome-dependent sampling, and the design and evaluation of vaccine efficacy trials.

Dr. Huang's recent work has focused on developing innovative statistical methodologies to improve analysis efficiency in small-scale studies by integrating external large databases, modeling and predicting the risk of recurrent events to identify high-risk individuals, and incorporating information on infecting pathogens in the analysis of vaccine trials with active or passive surveillance. Additionally, she has developed efficient statistical methods for analyzing survival data collected in prevalent cohort studies, benefit-risk assessment tools for evaluating treatment risks and benefits in patients with end-stage disease, and statistical methods that can account for informative clinic visits in the analysis of electronic health records.

In addition to her methodological research, Dr. Huang has extensive experience in collaborative research across a wide range of fields, including influenza, malaria, transplant, and cancer studies. During her tenure as a Mathematical Statistician at the National Institute of Allergy and Infectious Diseases (NIAID), she collaborated with both extramural and intramural scientists on the design, conduct, monitoring, analysis, and presentation of preclinical and clinical studies. She also served as a statistician to the NIAID Influenza Research Collaboration (NIRC) and the Mexican Emerging Infectious Disease Clinical Research Network (La Red), and received numerous awards for her collaborative research, including the prestigious NIAID Merit Award.

Since joining UCSF in 2017, Dr. Huang has served as the lead statistician for the Hematopoietic Malignancies Program at UCSF Helen Diller Family Comprehensive Cancer Center and the University of California Hematologic Malignancies Consortium (UCHMC). She also established and currently serves as the core director of the UCSF Department of Surgery Biostatistics Research Core, which provides statistical support to surgery investigators in designing and conducting rigorous, high-quality research.

Research Funding

  • August 1, 2022 - July 31, 2027 - The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation , Co-Investigator . Sponsor: NIH/NHLBI, Sponsor Award ID: U01HL163242
  • September 1, 2022 - August 31, 2025 - CF Statistical Expertise and Network (CF StatNet) Award , Statistician . Sponsor: Cystic Fibrosis Foundation, Sponsor Award ID: CFStatNet 003789Y7122
  • November 1, 2021 - January 31, 2025 - Mixed Data Meta-analysis: Integration of Individual Participant and Aggregate Data , Co-Investigator . Sponsor: PCORI, Sponsor Award ID: ME-2020C3-21269
  • June 15, 2018 - May 31, 2023 - Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation , Co-Investigator . Sponsor: NIH, Sponsor Award ID: R01AG059183

Education

National Tsing-Hua University, Hsinchu, Taiwan, B.S., 07/1994, Mathematics
National Tsing-Hua University, Hsinchu, Taiwan, M.S., 07/1996, Mathematics
Johns Hopkins University, Baltimore, Maryland, Ph.D., 05/2002, Biostatistics

Honors & Awards

  • 1991
    Invited Contestant, Asian Pacific Mathematics Olympiad (APMO)
  • 1991
    College admission for gifted students under Taiwan’s Special Education Act
  • 1991-1995
    Four-Year College Scholarship for Gifted Students in Mathematics and Sciences, Taiwanese Ministry of Education
  • 1992, 1993, 1994
    President’s Academic Awards (3 times), National Tsing-Hua University
  • 1994
    Graduated first in class from the Department of Mathematics, National Tsing-Hua University, Taiwan (completed a bachelor's degree in three years and admitted into graduate school without entrance exam)
  • 1997-2002
    Five-year departmental scholarship, Department of Biostatistics, Johns Hopkins University
  • 2002
    Margaret Merrell Award for Excellence in Research, Department of Biostatistics, Johns Hopkins University
  • 2004
    NIH Travel Award, ENAR Young Investigators Meeting
  • 2003-2005
    Grant-in-Aid of Research, Artistry, and Scholarship, University of Minnesota
  • 2005
    Performance Award for special achievement, Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, NIH
  • 2005, 2006, 2007, 2008, 2010, 2011
    Special Act or Service Award, National Institute of Allergy and Infectious Diseases, NIH
  • 2007
    NIAID Merit Award, National Institute of Allergy and Infectious Diseases, NIH

Selected Publications

  1. Sheng Y, Sun Y, McCulloch CE, Huang CY. Scalable estimation for high velocity survival data able to accommodate adding covariates. Statistica Sinica. 2024; 3(34).  View on PubMed
  2. Huang Y, Huang CY, Kim MO. Simultaneous selection and incorporation of consistent external aggregate information. Stat Med. 2023 Oct 03.  View on PubMed
  3. Shifman HP, Huang CY, Beck AF, Bucuvalas J, Perito ER, Hsu EK, Ebel NH, Lai JC, Wadhwani SI. Association of State Medicaid Expansion Policies with Pediatric Liver Transplant Outcomes. Am J Transplant. 2023 Sep 28.  View on PubMed
  4. Banerjee R, Huang CY, Ryan C, Lee A, Brassil KJ, Moore J, Arora S, Chung A, Wong SW, Wolf J, Martin T, Dhruva A, Shah N. Randomized phase 2 study of digital life coaching during transplantation for myeloma. Bone Marrow Transplant. 2023 Sep 25.  View on PubMed
  5. Ha NB, Fan B, Shui AM, Huang CY, Wadhwani S, Lai JC. Variation in skeletal muscle mass among patients with cirrhosis of different self-identified race/ethnicity. JGH Open. 2023.  View on PubMed
  6. Hennessy MA, Leal JP, Huang CY, Solnes LB, Denbow R, Abramson VG, Carey LA, Liu MC, Rimawi M, Specht J, Storniolo AM, Valero V, Vaklavas C, Winer EP, Krop IE, Wolff AC, Cimino-Mathews A, Wahl RL, Stearns V, Connolly RM. Correlation of SUV on Early Interim PET with Recurrence-Free Survival and Overall Survival in Primary Operable HER2-Positive Breast Cancer (the TBCRC026 Trial). J Nucl Med. 2023 Aug 31.  View on PubMed
  7. Duvalyan E, Shah N, Lo M, Martin T, Wolf JL, Chung A, Arora S, Huang CY, Wong SW. Impact of corticosteroids on efficacy of BCMA targeted CAR-T therapy in multiple myeloma. Leuk Lymphoma. 2023 Aug 21; 1-4.  View on PubMed
  8. McGarry ME, Huang CY, Ly NP. Ethnic differences in staphylococcus aureus acquisition in cystic fibrosis. J Cyst Fibros. 2023 Jul 15.  View on PubMed
  9. Xiong F, Wang J, Nierenberg JL, Van Blarigan EL, Kenfield SA, Chan JM, Schmajuk G, Huang CY, Graff RE. Diabetes mellitus and risk of breast cancer: a large-scale, prospective, population-based study. Br J Cancer. 2023 09; 129(4):648-655.  View on PubMed
  10. Qin J, Sun Y, Yuan A, Huang CY. . Maximum likelihood estimation for shape-restricted single-index hazard models. Journal of Data Science. 2023.  View on PubMed
  11. Banerjee R, Wang V, Huang CY, Pandita D, Leonard MK, LaRue S, Ahmadi M, Kaplan L, Ai WZ, Fakhri B, Spinner M, Seshadri MR, Pampaloni MH, Andreadis CB. Hypoxia-specific imaging in patients with lymphoma undergoing CAR-T therapy. Eur J Nucl Med Mol Imaging. 2023 Jun 10.  View on PubMed
  12. Singer JP, Gao Y, Huang CY, Kordahl RC, Sriram A, Hays SR, Kukreja J, Venado A, Calabrese DR, Greenland JR. The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation. Transplantation. 2023 10 01; 107(10):2255-2261.  View on PubMed
  13. Wang M, Ge J, Ha N, Shui AM, Huang CY, Cullaro G, Lai JC. Clinical Characteristics Associated With Posttransplant Survival Among Adults 70 Years Old or Older Undergoing Liver Transplantation. J Clin Gastroenterol. 2023 Jun 07.  View on PubMed
  14. Zafar A, Huang CY, Lo M, Arora S, Chung A, Wong SW, Wolf J, Martin TG, Shah N, Banerjee R. Intensity of Cyclophosphamide-Based Bridging Therapy Before Chimeric Antigen Receptor T Cell Therapy in Myeloma. Transplant Cell Ther. 2023 08; 29(8):504.e1-504.e7.  View on PubMed
  15. Nunez M, Praglin CR, Torres AM, Agudelo EZ, Braun HJ, Huang CY, Syed S, Roberts JP, Roll GR. Steroid Avoidance After Adult Living Donor Liver Transplant: A Cohort Analysis. Transplant Direct. 2023 Jun; 9(6):e1488.  View on PubMed
  16. Sun Y, Chiou SH, Wu CO, McGarry M, Huang CY. DYNAMIC RISK PREDICTION TRIGGERED BY INTERMEDIATE EVENTS USING SURVIVAL TREE ENSEMBLES. Ann Appl Stat. 2023 Jun; 17(2):1375-1397.  View on PubMed
  17. Natsuhara KH, Huang CY, Knoche J, Arora S, Chung A, Martin T, Wolf J, Wong SW, Shah N, Banerjee R. Significance of the pee-value: relevance of 24-hour urine studies for patients with myeloma. Leuk Lymphoma. 2023 06; 64(6):1186-1193.  View on PubMed
  18. Wang M, Shui AM, Barry F, Verna E, Kent D, Yao F, Seetharaman S, Berry K, Grubbs RK, George G, Huang CY, Duarte-Rojo A, Lai JC. The tele-liver frailty index (TeLeFI): development of a novel frailty tool in patients with cirrhosis via telemedicine. Am J Transplant. 2023 07; 23(7):966-975.  View on PubMed
  19. Greenberg AL, Barnes KE, Karimzada MM, Huang CY, Alseidi A, Rapp JH, O’Sullivan PS, Chern H, Syed SM. Difficult or high risk? Objective task assessment vs. faculty perceptions of surgical skills. Global Surgical Education. 2023.  View on PubMed
  20. Ha NB, Seetharaman S, Kent DS, Yao F, Shui AM, Huang CY, Walston J, Lai JC. Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis. Liver Transpl. 2023 Oct 01; 29(10):1089-1099.  View on PubMed

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