Research Summary

Dr. Chiung-Yu Huang is a Professor of Biostatistics at the Department of Epidemiology and Biostatistics at the University of California, San Francisco (UCSF) and serves as an Adjunct Professor at the Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center. Dr. Huang is a Fellow of the American Statistical Association (ASA) and is well known for her contributions to methodology research, particularly in the areas of survival analysis, competing risks analysis, recurrent event analysis, outcome-dependent sampling, and the design and evaluation of vaccine efficacy trials.

Dr. Huang's recent work has focused on developing innovative statistical methodologies to improve analysis efficiency in small-scale studies by integrating external large databases, modeling and predicting the risk of recurrent events to identify high-risk individuals, and incorporating information on infecting pathogens in the analysis of vaccine trials with active or passive surveillance. Additionally, she has developed efficient statistical methods for analyzing survival data collected in prevalent cohort studies, benefit-risk assessment tools for evaluating treatment risks and benefits in patients with end-stage disease, and statistical methods that can account for informative clinic visits in the analysis of electronic health records.

In addition to her methodological research, Dr. Huang has extensive experience in collaborative research across a wide range of fields, including influenza, malaria, transplant, and cancer studies. During her tenure as a Mathematical Statistician at the National Institute of Allergy and Infectious Diseases (NIAID), she collaborated with both extramural and intramural scientists on the design, conduct, monitoring, analysis, and presentation of preclinical and clinical studies. She also served as a statistician to the NIAID Influenza Research Collaboration (NIRC) and the Mexican Emerging Infectious Disease Clinical Research Network (La Red), and received numerous awards for her collaborative research, including the prestigious NIAID Merit Award.

Since joining UCSF in 2017, Dr. Huang has served as the lead statistician for the Hematopoietic Malignancies Program at UCSF Helen Diller Family Comprehensive Cancer Center and the University of California Hematologic Malignancies Consortium (UCHMC). She also established and currently serves as the core director of the UCSF Department of Surgery Biostatistics Research Core, which provides statistical support to surgery investigators in designing and conducting rigorous, high-quality research.

Research Funding

  • August 1, 2022 - July 31, 2027 - The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation , Co-Investigator . Sponsor: NIH/NHLBI, Sponsor Award ID: U01HL163242
  • September 1, 2022 - August 31, 2025 - CF Statistical Expertise and Network (CF StatNet) Award , Statistician . Sponsor: Cystic Fibrosis Foundation, Sponsor Award ID: CFStatNet 003789Y7122
  • November 1, 2021 - January 31, 2025 - Mixed Data Meta-analysis: Integration of Individual Participant and Aggregate Data , Co-Investigator . Sponsor: PCORI, Sponsor Award ID: ME-2020C3-21269
  • June 15, 2018 - May 31, 2023 - Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation , Co-Investigator . Sponsor: NIH, Sponsor Award ID: R01AG059183


National Tsing-Hua University, Hsinchu, Taiwan, B.S., 07/1994, Mathematics
National Tsing-Hua University, Hsinchu, Taiwan, M.S., 07/1996, Mathematics
Johns Hopkins University, Baltimore, Maryland, Ph.D., 05/2002, Biostatistics

Honors & Awards

  • 1991
    Invited Contestant, Asian Pacific Mathematics Olympiad (APMO)
  • 1991
    College admission for gifted students under Taiwan’s Special Education Act
  • 1991-1995
    Four-Year College Scholarship for Gifted Students in Mathematics and Sciences, Taiwanese Ministry of Education
  • 1992, 1993, 1994
    President’s Academic Awards (3 times), National Tsing-Hua University
  • 1994
    Graduated first in class from the Department of Mathematics, National Tsing-Hua University, Taiwan (completed a bachelor's degree in three years and admitted into graduate school without entrance exam)
  • 1997-2002
    Five-year departmental scholarship, Department of Biostatistics, Johns Hopkins University
  • 2002
    Margaret Merrell Award for Excellence in Research, Department of Biostatistics, Johns Hopkins University
  • 2004
    NIH Travel Award, ENAR Young Investigators Meeting
  • 2003-2005
    Grant-in-Aid of Research, Artistry, and Scholarship, University of Minnesota
  • 2005
    Performance Award for special achievement, Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, NIH
  • 2005, 2006, 2007, 2008, 2010, 2011
    Special Act or Service Award, National Institute of Allergy and Infectious Diseases, NIH
  • 2007
    NIAID Merit Award, National Institute of Allergy and Infectious Diseases, NIH

Selected Publications

  1. Sheng Y, Sun Y, McCulloch CE, Huang CY. Scalable estimation for high velocity survival data able to accommodate adding covariates. Statistica Sinica. 2024; 3(34).  View on PubMed
  2. Qin J, Sun Y, Yuan A, Huang CY. . Maximum likelihood estimation for shape-restricted single-index hazard models. Journal of Data Science. 2023.  View on PubMed
  3. Sun Y, Chiou SY, Wu CO, McGarry M, Huang CY. Dynamic risk prediction triggered by intermediate events using survival tree ensembles. Annals of Applied Statistics. 2023; 17(2):1375-1397.  View on PubMed
  4. Banerjee R, Huang CY, Ryan C, Lee A, Brassil KJ, Moore J, Arora S, Chung A, Wong SW, Wolf J, Martin T, Dhruva A, Shah N. Randomized phase 2 study of digital life coaching during transplantation for myeloma. Bone Marrow Transplantation. 2023.  View on PubMed
  5. Greenberg AL, Barnes KE, Karimzada MM, Huang CY, Alseidi A, Rapp JH, O’Sullivan PS, Chern H, Syed SM. Difficult or high risk? Objective task assessment vs. faculty perceptions of surgical skills. Journal of Surgical Education. 2023.  View on PubMed
  6. Singer JP, Gao Y, Huang CY, Hays SR, Kukreja J, Calabrese DR, Greenland JR. The association between frailty and chronic lung allograft dysfunction after lung transplantation. Transplantation. 2023.  View on PubMed
  7. Natsuhara KH, Huang CY, Knoche J, Arora S, Alfred Chung A, Martin T, Wolf J, Wong SW, Nina Shah N, Rahul Banerjee R. . Significance of the Pee-Value: Relevance of 24-hour urine studies for patients with myeloma. Leukemia & Lymphoma. 2023.  View on PubMed
  8. Nunez M, Praglin CR, Torres AM, Agudelo EZ, Braun HJ, Huang CY, Syed S, Roberts JP, Roll GR. Steroid avoidance after adult living donor liver transplant: a cohort analysis. Transplantation Direct. 2023.  View on PubMed
  9. Ha NB, Seetharaman S, Kent DS, Yao F, Shui AM, Huang CY, Walston J, Lai JC. Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis. Liver Transpl. 2023 Mar 20.  View on PubMed
  10. Reyes KR, Huang CY, Lo M, Arora S, Chung A, Wong SW, Wolf J, Olin RL, Martin T, Shah N, Banerjee R. Safety and efficacy of BCMA CAR-T cell therapy in older patients with multiple myeloma. Transplant Cell Ther. 2023 Mar 16.  View on PubMed
  11. Ge AY, Huang CY, Banerjee R, Knoche J, Chung A, Arora S, Martin TG, Wolf J, Wong SW, Wiita AP, Shah N. Cytomegalovirus seropositivity is associated with improved responses to CD38 monoclonal antibody therapies in multiple myeloma: A single-centre retrospective study. Br J Haematol. 2023 Feb 27.  View on PubMed
  12. Wang M, Huang CY, Cullaro G, Covinsky K, Lai JC. Women with cirrhosis have lower self-rated health than men. Hepatol Commun. 2023 03 01; 7(3):e0065.  View on PubMed
  13. Lai JC, Shui AM, Duarte-Rojo A, Rahimi RS, Ganger DR, Verna EC, Volk ML, Kappus M, Ladner DP, Boyarsky B, Segev DL, Gao Y, Huang CY, Singer JP. Association of Frailty With Health-Related Quality of Life in Liver Transplant Recipients. JAMA Surg. 2023 02 01; 158(2):130-138.  View on PubMed
  14. Chiou SY, Xu G, Yan J, Huang CY. Regression modeling for recurrent events possibly with an informative terminal event using R package reReg. Journal of Statistical Software. 2023; 105(5):1-34.  View on PubMed
  15. Ha NB, Fan B, Shui AM, Huang CY, Brandman D, Lai JC. CT-quantified sarcopenic visceral obesity is associated with poor transplant waitlist mortality in patients with cirrhosis. Liver Transpl. 2023 May 01; 29(5):476-484.  View on PubMed
  16. Cheng YW, McLean R, Sewell JL, Huang CY, Khalili M. Inflammatory bowel disease type influences development of elevated liver enzymes. JGH Open. 2022 Dec; 6(12):846-853.  View on PubMed
  17. Huang MY, Huang CY. Improved semiparametric estimation of the proportional rate model with recurrent event data. Biometrics. 2022 Oct 31.  View on PubMed
  18. Cheng YJ, Liu YC, Tsai CY, Huang CY. Semiparametric estimation of the transformation model by leveraging external aggregate data in the presence of population heterogeneity. Biometrics. 2022 Oct 31.  View on PubMed
  19. Greenberg AL, Karimzada MM, Brian R, Yap A, Luu HY, Ahmed S, Huang CY, Waits SA, Hirose R, Alseidi A, Rapp JH, O'Sullivan PS, Chern H, Syed SM. Assessment of Surgeon Performance of Advanced Open Surgical Skills Using a Microskills-Based Novel Curriculum. JAMA Netw Open. 2022 09 01; 5(9):e2229787.  View on PubMed
  20. Chung A, Banbury B, Vignali M, Huang CY, Asoori S, Johnson R, Kurtz T, Arora S, Wong SW, Shah N, Martin TG, Wolf JL. Antibody and T-cell responses by ultra-deep T-cell receptor immunosequencing after COVID-19 vaccination in patients with plasma cell dyscrasias. Br J Haematol. 2022 11; 199(4):520-528.  View on PubMed

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