Joseph O. Humtsoe, PhD
Associate Researcher, Dept. of Otolaryngology, Head and Neck Surgery, UCSF
Education
Science College Kohima, Kohima, Nagaland, BS, 1993, Life sciences
North Eastern Hill University, Shillong, Meghalaya, MS, 1995, Biochemistry
North Eastern Hill University, Shillong, Meghalaya, PhD, 2000, Biochemistry
University of Houston, Texas, Postdoctoral Fellow, 2004, Cell and Molecular Biology
Honors & Awards
- 1996
Junior Research Fellowship, University Grants Commission, New Delhi, INDIA - 1998
Senior Research Fellowship, University Grants Commission, New Delhi, INDIA - 1999
Guest Scientist to Institute of Medicine, Research Center, Juelich, Germany - 2000
"Dr. A. R. Gopal-Ayenger Best Poster Award" at the International Conference on Radiation Biology- RADIOBIOLOGY 2000, Regional Cancer Center, Trivandrum, India
Selected Publications
- Humtsoe JO, Kim HS, Jones L, Cevallos J, Boileau P, Kuo F, Morris LGT, Ha P. Development and Characterization of MYB-NFIB Fusion Expression in Adenoid Cystic Carcinoma. Cancers (Basel). 2022 Apr 30;14(9):2263.
View on PubMed - Humtsoe JO, Kim HS, Leonard B, Ling S, Keam B, Marchionni L, Afsari B, Considine M, Favorov AV, Fertig EJ, Kang H, Ha PK. Newly Identified Members of FGFR1 Splice Variants Engage in Cross-talk with AXL/AKT Axis in Salivary Adenoid Cystic Carcinoma. Cancer Res. 2021 Feb 15;81(4):1001-1013.
View on PubMed - Park S, Vora M, van Zante A, Humtsoe J, Kim HS, Yom S, Agarwal S, Ha P. Clinicopathologic implications of Myb and Beta-catenin expression in adenoid cystic carcinoma. J Otolaryngol Head Neck Surg. 2020 Jul 10;49(1):48.
View on PubMed - Humtsoe JO, Pham E, Louie RJ, Chan DA, Kramer RH. ErbB3 upregulation by the HNSCC 3D microenvironment modulates cell survival and growth. Oncogene. 2015.
View on PubMed - Humtsoe JO, Koya E, Pham E, Aramoto T, Zuo J, et al. Transcriptional profiling identifies upregulated genes following induction of epithelial-mesenchymal transition in squamous carcinoma cells. Experimental cell research. 2012; 318(4):379-90.
View on PubMed - Chatterjee I, Humtsoe JO, Kohler EE, Sorio C, Wary KK. Lipid phosphate phosphatase-3 regulates tumor growth via β-catenin and CYCLIN-D1 signaling. Molecular cancer. 2011; 10:51.
View on PubMed - Humtsoe JO, Liu M, Malik AB, Wary KK. Lipid phosphate phosphatase 3 stabilization of beta-catenin induces endothelial cell migration and formation of branching point structures.Molecular and cellular biology. 2010; 30(7):1593-606.
View on PubMed - Humtsoe JO, Kramer RH.Differential epidermal growth factor receptor signaling regulates anchorage-independent growth by modulation of the PI3K/AKT pathway. Oncogene. 2010; 29(8):1214-26.
View on PubMed - Zuo J, Ishikawa T, Boutros S, Xiao Z, Humtsoe JO, et al. Bcl-2 overexpression induces a partial epithelial to mesenchymal transition and promotes squamous carcinoma cell invasion and metastasis. Molecular cancer research : MCR. 2010; 8(2):170-82.
View on PubMed - Onishi A, Chen Q, Humtsoe JO, Kramer RH. STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells. Experimental cell research. 2008; 314(2):377-86.
View on PubMed