Research Funding

  • June 1, 2024 - May 31, 2029 - Using microvolumetric cyst fluid proteolysis for early detection of pancreatic cancer , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01CA282269
  • May 16, 2023 - April 30, 2028 - Advancing the Clinical Translation of Cyst Fluid Assays for Early Detection of Pancreatic Cancer , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01CA271250
  • July 1, 2015 - June 30, 2021 - Molecular Correlates of progression in pancreatic cystic neoplasms , Site Principal Investigator, UCSF . Sponsor: NCI/NIH, Sponsor Award ID: U01
  • November 1, 2017 - November 1, 2020 - Minimally Invasive Classification of Pancreatic Cystic Neoplasms , Principal Investigator . Sponsor: V Foundation, Sponsor Award ID: T2017-013
  • February 1, 2017 - June 30, 2018 - Development of fluorogenic substrates for the diagnosis of pancreatic cysts , Principal Investigator . Sponsor: UCSF Clinical and Translational Sciences Institute, Sponsor Award ID: Catalyst Awards Program
  • January 1, 2015 - December 31, 2017 - Non-invasive Differentiation of Benign Lesions from Aggressive Pancreatic Cancer , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21CA185689
  • May 15, 1994 - March 31, 2014 - Neural Regulation of Pancreatic Function , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01DK046285

Education

Reed College, Portland, OR, B.A., 1977-1981, Biology
University of Pennsylvania School of Medicine, Philadelphia, PA, M.D., 1981-1985, Medicine

Honors & Awards

Past Research Support (Selected)

  • 1981
    Phi Beta Kappa National Honor Society
  • 1981
    Walter Croll Scholarship, University of Pennsylvania School of Medicine
  • 1983-85
    President, Alpha Omega Alpha National Medical Honor Society, University of Pennsylvania Chapter
  • 1989-90
    Claude E. Welch Research Fellowship Award, Department of Surgery, Mass General Hospital
  • 1990-91
    Claude E. Welch Research Fellowship Award, Department of Surgery, Mass General Hospital
  • 1995-96
    Nominated, Kaiser Award for Excellence in Teaching, UCSF School of Medicine
  • 1996-97
    Excellence in Teaching, UCSF Department of Surgery Chief Residents
  • 1998
    Clinical Teaching Award, UCSF School of Medicine, Class of 1998
  • 1999
    Nominated, Kaiser Award for Excellence in Teaching, Medical Students
  • 2001
    Excellence in Teaching Award, UCSF Department of Surgery Residents
  • 2004
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2004
    Kaiser Award for Excellence in Teaching Nomination, UCSF School of Medicine
  • 2008
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2009
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2010
    AGA Student Abstract Prize (Victoria Lyo), American Gastroenterological Association (AGA) Foundation
  • 2010
    Kaiser Award for Excellence in Teaching Nomination, UCSF School of Medicine
  • 2010
    Pancreas Club Warren Award (Victoria Lyo), Pancreas Club
  • 2010
    Howard Hughes Research Fellowship (Victoria Lyo), Howard Hughes Medical Institute
  • 2012
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2013
    Excellence in Teaching Award, UCSF School of Medicine, Surgical Clerkship
  • 2014
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2015
    Excellence in Teaching Award, Inaugural, UCSF Department of Surgery Junior Residents
    • 7/2013-6/2014
      CTSI Phase 1, TI Catalyst: Early Diagnosis of Pancreatic Cancer Using a Non-Invasive Imaging Tool
    • 7/2013-6/2014
      UCSF RAP Cancer Pilot: Non-Invasive Imaging of Proteolytic Activity in the Pancreas: Towards Early Diagnosis of Pancreatic Cancer
    • 04/01/03-03/31/14
      R01 DK46285 (no cost extension) NIH: Neural Regulation of Pancreatic Function
      The major goals of this project are to examine the role of proteases, sensory nerves, tachykinins, ion channels, and neurokinin receptors in pancreatic inflammation and pain.
    • 07/01/2009-06/30/12
      2T32DK07573-21 NIH: GI Training Grant
      The goal of this project is to provide 2 years of independent research training to fellows with academic career goals in the field of gastrointestinal surgery. Dr. Kirkwood has mentored 8 surgical research fellows in 17 years.
    • 02/01/10-01/31/11
      3R01DK046285-10S1 NIH: Neural Regulation of Pancreatic Function (Recovery Act Administrative Supplement)
      The purpose of this study is to further to examine the role of proteases, sensory nerves, tachykinins, ion channels, and neurokinin receptors in pancreatic inflammation and pain.
    • 07/01/2010-06/30/11
      Foundation - Greenwall Foundation (Co PI: Kirkwood, Lo) Ethics of Informed Consent for Innovative surgical procedures
      The purpose of this study is to develop an understanding of the ethical and legal issues that surround informed consent for innovative surgical procedures.
    • 04/01/08-03/31/13
      2 R01 DK046285-14 NIH: Neural Regulation of Pancreatic Function
      The major goals of this project are to examine the role of proteases, sensory nerves, tachykinins, ion channels, and neurokinin receptors in pancreatic inflammation and pain.

Selected Publications

  1. Wong P, Todeschini L, Pollini T, Hernandez S, Zampese M, Aguilar LL, Peng JS, Thornblade LW, Adam MA, Alseidi A, Corvera CU, Hirose K, Kirkwood KS, Nakakura EK, Maker AV. Minimally Invasive Versus Open Resection for Solid Pseudopapillary Tumors of the Pancreas: A Propensity Score-Matched Analysis. J Surg Oncol. 2025 Sep; 132(4):676-683. View on PubMed
  2. Maher MH, Treekitkarnmongkol W, Ghatak S, Dai J, Liu S, Nguyen T, Duose DY, Kim MP, Hu TY, Hurd MW, Paris PL, Kirkwood KS, Maitra A, Luthra R, Sen S, Roy-Chowdhuri S. An integrated multi-omics biomarker approach using molecular profiling and microRNAs for evaluation of pancreatic cyst fluid. View on PubMed
  3. Yin H, Sharma D, Wang JJ, Ganjouei AA, Kouanda A, Hirose K, Nakakura E, Kirkwood K, Corvera C, Alseidi A, Adam MA. Robotic-assisted trans-mesocolic side-to-side duodenojejunostomy for palliative management of malignant distal duodenal obstruction. Chin Clin Oncol. 2025 Feb; 14(1):5. View on PubMed
  4. Yin H, Romero-Hernandez F, Ganjouei AA, Wang JJ, Brown A, Hirose K, Maker AV, Nakakura E, Corvera C, Kirkwood KS, Wilhelm A, Peng JS, Alseidi A, Adam MA. Adult Pancreatoblastoma: Clinical Insights and Outcomes Compared to Pancreatic Ductal Adenocarcinoma (PDAC). Curr Oncol. 2024 08 28; 31(9):5008-5020. View on PubMed
  5. Hoffman D, Ganjouei AA, Hernandez FR, Ifuku K, Miller P, Glencer A, Corvera C, Kirkwood K, Alseidi A, Adam M, Maker A, Hirose K, Hirose R, Nakakura EK. Graft choice in pancreatectomy with vascular resection: equivalent safety in selected patients. J Gastrointest Surg. 2024 11; 28(11):1799-1804. View on PubMed
  6. Miller PN, Romero-Hernandez F, Calthorpe L, Wang JJ, Kim SS, Corvera CU, Hirose K, Kirkwood KS, Hirose R, Maker AV, Alseidi AA, Adam MA, Kim GE, Tempero MA, Ko AH, Nakakura EK. ASO Visual Abstract: Long-Duration Neoadjuvant Therapy with FOLFIRINOX Yields Favorable Outcomes for Patients Who Undergo Surgery for Pancreatic Cancer. Ann Surg Oncol. 2024 Jul 27. View on PubMed
  7. Wong P, Pollini T, Adam MA, Alseidi A, Corvera CU, Hirose K, Kirkwood KS, Nakakura EK, Thornblade L, Maker AV. Distinct Indications for Adjuvant Therapy in Resected Invasive Mucinous Cystic Neoplasms of the Pancreas Compared with Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol. 2024 Nov; 31(12):8276-8286. View on PubMed
  8. Miller PN, Romero-Hernandez F, Calthorpe L, Wang JJ, Kim SS, Corvera CU, Hirose K, Kirkwood KS, Hirose R, Maker AV, Alseidi AA, Adam MA, Kim GE, Tempero MA, Ko AH, Nakakura EK. Long-Duration Neoadjuvant Therapy with FOLFIRINOX Yields Favorable Outcomes for Patients Who Undergo Surgery for Pancreatic Cancer. Ann Surg Oncol. 2024 Sep; 31(9):6147-6156. View on PubMed
  9. Casey M, Brown A, Romero-Hernandez F, Wang JJ, Ganjouei AA, Tozzi F, Rashidian N, Kirkwood K, Corvera C, Nakakura E, Alseidi A, Adam M. National practice patterns in the use of endoscopic ultrasound biopsy for resectable Pancreatic Neuroendocrine Tumors: Insights into the role of DOTATATE PET/CT in diagnosis. Am J Surg. 2024 Sep; 235:115779. View on PubMed
  10. Ashraf Ganjouei A, Romero-Hernandez F, Conroy PC, Miller PN, Calthorpe L, Wang JJ, Lin JJ, Feng J, Kirkwood KS, Alseidi A, Sarin A, Adam MA. A Novel Machine Learning Approach to Predict Textbook Outcome in Colectomy. Dis Colon Rectum. 2024 Feb 01; 67(2):322-332. View on PubMed
  11. Sheik DA, Byers K, Thomas M, Rajesh UC, Ifuku K, Kirkwood K, Al-Haddad M, Craik CS, Davisson VJ. Addressing the unmet clinical need for low-volume assays in early diagnosis of pancreatic cancer. Front Gastroenterol (Lausanne). 2023; 2. View on PubMed
  12. Ashraf Ganjouei A, Romero-Hernandez F, Wang JJ, Casey M, Frye W, Hoffman D, Hirose K, Nakakura E, Corvera C, Maker AV, Kirkwood KS, Alseidi A, Adam MA. A Machine Learning Approach to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy Using Only Preoperatively Known Data. Ann Surg Oncol. 2023 Nov; 30(12):7738-7747. View on PubMed
  13. Calthorpe L, Romero-Hernandez F, Casey M, Nunez M, Conroy PC, Hirose K, Kim A, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA. ASO Visual Abstract: National Practice Patterns in Malignant Peritoneal Mesothelioma-Updates in Management and Survival. Ann Surg Oncol. 2023 Aug; 30(8):5131. View on PubMed
  14. Calthorpe L, Romero-Hernandez F, Casey M, Nunez M, Conroy PC, Hirose K, Kim A, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA. National Practice Patterns in Malignant Peritoneal Mesothelioma: Updates in Management and Survival. Ann Surg Oncol. 2023 Aug; 30(8):5119-5129. View on PubMed
  15. Zhu G, Ifuku KA, Kirkwood KS. Robotic-assisted approach for complex cholecystectomies. Mini Invasive Surg. 2023; 7. View on PubMed
  16. Lin JJ, Conroy PC, Romero-Hernandez F, Yilma M, Feng J, Hirose K, Nakakura E, Maker AV, Corvera C, Kirkwood K, Alseidi A, Adam MA. Hypertension Requiring Medication Use: a Silent Predictor of Poor Outcomes After Pancreaticoduodenectomy. J Gastrointest Surg. 2023 02; 27(2):328-336. View on PubMed
  17. Calthorpe L, Romero-Hernandez F, Miller P, Conroy PC, Hirose K, Kim A, Kirkwood K, Nakakura E, Corvera C, Maker AV, Alseidi A, Adam MA. Contemporary Trends in Malignant Peritoneal Mesothelioma: Incidence and Survival in the United States. Cancers (Basel). 2022 Dec 30; 15(1). View on PubMed
  18. Conroy PC, Mohamedaly S, Karimzada M, Brian R, Im C, Hernandez S, Roman S, Hirose K, Mukhtar R, Kirkwood K, O'Sullivan P, Alseidi A. Implementation, evaluation, and modification of a near-peer learning group in graduate surgical education. Am J Surg. 2023 03; 225(3):591-592. View on PubMed
  19. Miller PN, Romero-Hernandez F, Conroy P, Calthorpe L, Yilma M, Mohamedaly S, Kelly YM, Feng J, Hirose K, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA. Hand-Assisted Versus Pure Minimally-Invasive Distal Pancreatectomy: Is There a Downside to Lending a Hand? World J Surg. 2023 03; 47(3):750-758. View on PubMed
  20. Romero-Hernandez F, Mohamedaly S, Miller P, Rodriguez N, Calthorpe L, Conroy PC, Ganjouei AA, Hirose K, Maker AV, Nakakura E, Corvera C, Kirkwood KS, Alseidi A, Adam MA. Minimally Invasive Distal Pancreatectomy Techniques: A Contemporary Analysis Exploring Trends, Similarities, and Differences to Open Surgery. Cancers (Basel). 2022 Nov 16; 14(22). View on PubMed

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