Research Summary
I am a Professor in the Department of Laboratory Medicine and the Helen Diller Family Comprehenive Cancer Center at the University of California San Francisco. I am a board-certified hematopathologist with 17 years in active practice diagnosing lymphomas, leukemias, and other hematologic disorders. As a past chair of the Hematopathology subcommittee of the National Cancer Institute’s Mouse Models of Human Cancers Consortium, I am an internationally recognized expert in the characteri¬zation and classification of hematopoietic neoplasms in mice as well as in humans. I am also a noted researcher in the molecular pathogenesis of leukemia, including in the role of MYC in hematologic malignancy. My hematopathology training and research background combine to facilitate consultations and collaborations with investigators at UCSF, nationally, and internationally. I use my expertise in the pathology of humans and mice, as well as my experience in clinical pathology/laboratory medicine, to direct the mouse pathology core of the UCSF HDFCCC.
Research Funding
September 25, 2009 - June 30, 2019 - Center for Integrative Research on Childhood Leukemia and the Environment, Co-Investigator. Sponsor: NIH, Sponsor Award ID: P50ES018172
June 1, 2014 - May 31, 2019 - Impact of low IL-10 levels at birth and leukemia risk, Co-Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R01CA185058
February 1, 2013 - January 31, 2015 - Impact of B-Cell Lineage on Progression of B-Acute Lymphoblastic Leukemia, Co-Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R21CA173028
April 1, 2002 - March 31, 2008 - Molecular Mechanisms of Leukemogenesis by PMLRAR alpha, Principal Investigator. Sponsor: NIH/NCI, Sponsor Award ID: R01CA095274
Education
Harvard College, Cambridge, MA, A.B., 1986, Biochemical Sciences
University of California San Francisco, M.D., 1991, Medicine
Laboratory Medicine Residency, UCSF, 1991-1993, Laboratory Medicine
Hematopathology Fellowship, UCSF, 1997-1998, Hematopathology