Dr. Krishna Komanduri

Krishna Komanduri, MD

Julius R. Krevans, M.D., Distinguished Professorship in Internal Medicine, UCSF

Professor and Chief, Division of Hematology and Oncology, Dept. of Medicine; Physician-in-Chief, Helen Diller Family Comprehensive Cancer Center; Clinical Director, Living Therapeutics Initiative, UCSF

[email protected]

Box 0324, UCSF
San Francisco, CA 94143

UCSF Profiles

Research Funding

  • August 22, 2011 - June 30, 2024 - Reduction of Relapse Risk Through Incorporation of Novel Biologic Agents Following Reduced Intensity Haploidentical Donor Transplant for Acute Myeloid Leukemia. , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: UG1HL109526
  • February 11, 2008 - December 31, 2012 - Immune Reconstitution After Cord Blood Transplantation , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01HL091749
  • September 28, 2005 - May 31, 2012 - T Cell Reconstitution After Allogeneic SCT , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01CA109326

Education

06/1999 - Postdoctoral Fellowship, Immunology, Gladstone Institute of Virology & Immunology
06/1997 - Hematology/Oncology Fellowship, UCSF
06/1994 - Internal Medicine Residency, UCLA Center for Health Sciences
M.D., 06/1991 - Medicine, University of Minnesota Medical School
S.B., 06/1987 - Biology, Literature, Massachusetts Institute of Technology

Honors & Awards

  • Elected, Henry Kunkel Society, 2021
  • Honorary Fellow, American Society for Transplantation and Cellular Therapy, 2021
  • Best Doctors in America, 2013-2021
  • Elected, American Society for Clinical Investigation, 2009
  • Division of Cancer Medicine Leadership in Education Award, University of Texas M.D. Anderson Cancer Center, 2008
  • Solomon Scholar Research Award, UCLA School of Medicine, 1994
  • President's Student Leadership and Service Award, University of Minnesota, 1991
  • Merck Foundation Graduating Medical Student Award, University of Minnesota Medical School, 1991
  • Minnesota Medical Foundation Outstanding Student Award, University of Minnesota Medical School, 1991
  • National Merit Scholar, 1983

Selected Publications

  1. Rueda-Lara M, Barrera I, Komanduri KV, Pereira D, Lekakis L, Wang TP, Jimenez AM, Beitinjaneh A, Holtzman NG, Green DJ, Goodman M, Benjamin CL, Spiegel J, Lehardy EN, Antoni MH, Goldstein H, Harvey PD, Wright BJ. Psychosocial correlates of failure to complete hematopoietic stem cell transplants in a diverse population. Bone Marrow Transplant. 2025 Jun 02.  View on PubMed
  2. Fleszar-Pavlovic SE, Noriega Esquives B, Lovan P, Brito AE, Sia AM, Kauffman MA, Lopes M, Moreno PI, Koru-Sengul T, Gong R, Wang T, Wieder ED, Rueda-Lara M, Antoni M, Komanduri K, Lesiuk T, Penedo FJ. Development of an eHealth Mindfulness-Based Music Therapy Intervention for Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: Qualitative Study. JMIR Form Res. 2025 Apr 11; 9:e65188.  View on PubMed
  3. Pearson ADJ, Rossig C, Mackall CL, Shah NN, Baruchel A, Daems S, Anderson J, Biondi A, Bird N, Bodmer N, Brivio E, Buechner J, Calkoen FG, Cooper T, de Rojas T, Fox E, Gardner R, Ghorashian S, Heenen D, Ifversen M, Jacoby E, Juan M, Knox L, Komanduri K, Larghero J, Locatelli F, Ludwinski D, Majzner RG, McDonough J, Minard-Colin V, Nysom K, Pappo A, Park JR, Qasim W, Quintarelli C, Rives S, Rouce RH, Scobie N, Seitz C, Tasian SK, Weigel B, Weiner S, Zwaan CM, Vassal G. New models for the development of and access to CAR T-cell therapies for children and adolescents with cancer: an ACCELERATE multistakeholder analysis. Lancet Oncol. 2025 Apr; 26(4):e214-e224.  View on PubMed
  4. Locke FL, Mahmoudjafari Z, Kebriaei P, Gardner RA, Frigault MJ, Frey NV, Komanduri KV, Perales MA, Nikiforow S. Awakening from REMS: ASTCT 80/20 Ongoing Recommendations for Safe Use of Chimeric Antigen Receptor T Cells. Transplant Cell Ther. 2025 Feb 13.  View on PubMed
  5. Amaria RN, Komanduri KV, Schoenfeld AJ, Ramsingh G, Burga RA, Jagasia MH. Entering a new era of tumor-infiltrating lymphocyte cell therapy innovation. Cytotherapy. 2024 Dec 28.  View on PubMed
  6. Lin RY, Anderson AD, Natori Y, Raja M, Morris MI, Jimenez AJ, Beitinjaneh A, Wang T, Goodman M, Lekakis L, Spiegel J, Holtzman NG, Pereira D, Benjamin C, Natori A, Komanduri KV, Camargo JF. Incidence and outcomes of cytomegalovirus reactivation after chimeric antigen receptor T-cell therapy. Blood Adv. 2024 07 23; 8(14):3813-3822.  View on PubMed
  7. Gritti G, Belousov A, Relf J, Dixon M, Tandon M, Komanduri K. Predictive model for the risk of cytokine release syndrome with glofitamab treatment for diffuse large B-cell lymphoma. Blood Adv. 2024 07 23; 8(14):3615-3618.  View on PubMed
  8. Fleszar-Pavlovic SE, Esquives BN, Brito AE, Sia AM, Kauffman MA, Lopes M, Moreno PI, Koru-Sengul T, Gong R, Wang T, Wieder ED, Rueda-Lara M, Antoni M, Komanduri K, Lesiuk T, Penedo FJ. eHealth mindfulness-based music therapy for patients undergoing allogeneic hematopoietic stem cell transplantation: A pilot randomized controlled trial protocol. Contemp Clin Trials. 2024 Jul; 142:107577.  View on PubMed
  9. Gardner RA, White C, Elsallab M, Farnia S, Fraint E, Grilley B, Bateman-House A, Grupp SA, Kenderian S, Locke FL, Nikiforow S, Oluwole OO, Rouce RH, Spiegel J, Shah NN, Sharma A, Komanduri K, Gill S. ACT To Sustain: Adoptive Cell Therapy To Sustain Access to Non-Commercialized Genetically Modified Cell Therapies. Transplant Cell Ther. 2024 Aug; 30(8):776-787.  View on PubMed
  10. Copsel SN, Garrido VT, Barreras H, Bader CS, Pfeiffer B, Mateo-Victoriano B, Wolf D, Gallardo M, Paczesny S, Komanduri KV, Benjamin CL, Villarino AV, Saluja AK, Levy RB. Minnelide suppresses GVHD and enhances survival while maintaining GVT responses. JCI Insight. 2024 Apr 11; 9(9).  View on PubMed
  11. Betof Warner A, Hamid O, Komanduri K, Amaria R, Butler MO, Haanen J, Nikiforow S, Puzanov I, Sarnaik A, Bishop MR, Schoenfeld AJ. Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy. J Immunother Cancer. 2024 02 29; 12(2).  View on PubMed
  12. Spinner MA, Komanduri KV. Long-term Survivors and Failures of CAR-T Therapy for Lymphoma: Is there a Role for Allogeneic Transplantation After the CAR-T Crash? Transplant Cell Ther. 2023 Dec; 29(12):725-726.  View on PubMed
  13. Khatri AM, Natori Y, Anderson A, Jabr R, Shah SA, Natori A, Chandhok NS, Komanduri K, Morris MI, Camargo JF, Raja M. Breakthrough invasive fungal infections on isavuconazole prophylaxis in hematologic malignancy & hematopoietic stem cell transplant patients. Transpl Infect Dis. 2023 Nov; 25 Suppl 1:e14162.  View on PubMed
  14. Bianchi A, De Castro Silva I, Deshpande NU, Singh S, Mehra S, Garrido VT, Guo X, Nivelo LA, Kolonias DS, Saigh SJ, Wieder E, Rafie CI, Dosch AR, Zhou Z, Umland O, Amirian H, Ogobuiro IC, Zhang J, Ban Y, Shiau C, Nagathihalli NS, Montgomery EA, Hwang WL, Brambilla R, Komanduri K, Villarino AV, Toska E, Stanger BZ, Gabrilovich DI, Merchant NB, Datta J. Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer. Cancer Discov. 2023 06 02; 13(6):1428-1453.  View on PubMed
  15. Benjamin CL, Desai S, Pereira D, Beitinjaneh A, Jimenez A, Goodman M, Lekakis L, Spiegel J, Komanduri KV, Wang TP. Cryopreservation and storage patterns of hematopoietic progenitor stem cells for multiple myeloma. Transfus Apher Sci. 2023 Oct; 62(5):103731.  View on PubMed
  16. Hines MR, Knight TE, McNerney KO, Leick MB, Jain T, Ahmed S, Frigault MJ, Hill JA, Jain MD, Johnson WT, Lin Y, Mahadeo KM, Maron GM, Marsh RA, Neelapu SS, Nikiforow S, Ombrello AK, Shah NN, Talleur AC, Turicek D, Vatsayan A, Wong SW, Maus MV, Komanduri KV, Berliner N, Henter JI, Perales MA, Frey NV, Teachey DT, Frank MJ, Shah NN. Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome. Transplant Cell Ther. 2023 07; 29(7):438.e1-438.e16.  View on PubMed
  17. Lin RY, Anderson AD, Morris MI, Raja M, Komanduri KV, Camargo JF. Successful restoration of protective immunity against measles, mumps, and rubella following MMR vaccination in adult hematopoietic cell transplant recipients. Transpl Infect Dis. 2023 Apr; 25(2):e14043.  View on PubMed
  18. Barreras H, Copsel SN, Bader CS, Ding Y, Wolf D, Cash C, Stacey CJ, Benjamin C, Seavey MM, Wolf J, Jasuja RR, Pfeiffer B, Hill GR, Komanduri KV, Jurecic R, Malek TR, Levy RB. Regulatory T Cell Amelioration of Graft-versus-Host Disease following Allogeneic/Xenogeneic Hematopoietic Stem Cell Transplantation Using Mobilized Mouse and Human Peripheral Blood Donors. Transplant Cell Ther. 2023 05; 29(5):341.e1-341.e9.  View on PubMed
  19. Nikiforow S, Frigault MJ, Frey NV, Gardner RA, Komanduri KV, Perales MA, Kebriaei P, Warkentin PI, Pasquini M, Aho JL, Levine BL, Heslop HE, Hlucky TL, Habucky K, Gharibo M, Jagasia M, Locke FL. Paving the Road for Chimeric Antigen Receptor T Cells: American Society for Transplantation and Cellular Therapy 80/20 Task Force Consensus on Challenges and Solutions to Improving Efficiency of Clinical Center Certification and Maintenance of Operations for Commercially Approved Immune Effector Cell Therapies. Transplant Cell Ther. 2023 04; 29(4):228-239.  View on PubMed
  20. Shah AM, Galor A, Mones K, Jean P, Komanduri KV, Wang TP. Conjunctival inflammation and dry eye symptoms at day 100 post-transplantation do not predict risk for chronic graft-versus-host disease. Taiwan J Ophthalmol. 2023 Jan-Mar; 13(1):43-48.  View on PubMed

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