Dr. Krishna Komanduri

Krishna Komanduri, MD

Julius R. Krevans, M.D., Distinguished Professorship in Internal Medicine, UCSF

Professor and Chief, Division of Hematology and Oncology, Dept. of Medicine; Physician-in-Chief, Helen Diller Family Comprehensive Cancer Center; Clinical Director, Living Therapeutics Initiative, UCSF

[email protected]

Box 0324, UCSF
San Francisco, CA 94143

UCSF Profiles

Research Funding

  • August 22, 2011 - June 30, 2024 - Reduction of Relapse Risk Through Incorporation of Novel Biologic Agents Following Reduced Intensity Haploidentical Donor Transplant for Acute Myeloid Leukemia. , Co-Principal Investigator . Sponsor: NIH, Sponsor Award ID: UG1HL109526
  • February 11, 2008 - December 31, 2012 - Immune Reconstitution After Cord Blood Transplantation , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01HL091749
  • September 28, 2005 - May 31, 2012 - T Cell Reconstitution After Allogeneic SCT , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01CA109326

Honors & Awards

  • Elected, Henry Kunkel Society, 2021
  • Honorary Fellow, American Society for Transplantation and Cellular Therapy, 2021
  • Best Doctors in America, 2013-2021
  • Elected, American Society for Clinical Investigation, 2009
  • Division of Cancer Medicine Leadership in Education Award, University of Texas M.D. Anderson Cancer Center, 2008
  • Solomon Scholar Research Award, UCLA School of Medicine, 1994
  • President's Student Leadership and Service Award, University of Minnesota, 1991
  • Merck Foundation Graduating Medical Student Award, University of Minnesota Medical School, 1991
  • Minnesota Medical Foundation Outstanding Student Award, University of Minnesota Medical School, 1991
  • National Merit Scholar, 1983

Selected Publications

  1. Khatri AM, Natori Y, Anderson A, Jabr R, Shah SA, Natori A, Chandhok NS, Komanduri K, Morris MI, Camargo JF, Raja M. Breakthrough invasive fungal infections on isavuconazole prophylaxis in hematologic malignancy & hematopoietic stem cell transplant patients. Transpl Infect Dis. 2023 Oct 04; e14162.  View on PubMed
  2. Bianchi A, De Castro Silva I, Deshpande NU, Singh S, Mehra S, Garrido VT, Guo X, Nivelo LA, Kolonias DS, Saigh SJ, Wieder E, Rafie CI, Dosch AR, Zhou Z, Umland O, Amirian H, Ogobuiro IC, Zhang J, Ban Y, Shiau C, Nagathihalli NS, Montgomery EA, Hwang WL, Brambilla R, Komanduri K, Villarino AV, Toska E, Stanger BZ, Gabrilovich DI, Merchant NB, Datta J. Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer. Cancer Discov. 2023 06 02; 13(6):1428-1453.  View on PubMed
  3. Benjamin CL, Desai S, Pereira D, Beitinjaneh A, Jimenez A, Goodman M, Lekakis L, Spiegel J, Komanduri KV, Wang TP. Cryopreservation and storage patterns of hematopoietic progenitor stem cells for multiple myeloma. Transfus Apher Sci. 2023 May 20; 103731.  View on PubMed
  4. Hines MR, Knight TE, McNerney KO, Leick MB, Jain T, Ahmed S, Frigault MJ, Hill JA, Jain MD, Johnson WT, Lin Y, Mahadeo KM, Maron GM, Marsh RA, Neelapu SS, Nikiforow S, Ombrello AK, Shah NN, Talleur AC, Turicek D, Vatsayan A, Wong SW, Maus MV, Komanduri KV, Berliner N, Henter JI, Perales MA, Frey NV, Teachey DT, Frank MJ, Shah NN. Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome. Transplant Cell Ther. 2023 07; 29(7):438.e1-438.e16.  View on PubMed
  5. Lin RY, Anderson AD, Morris MI, Raja M, Komanduri KV, Camargo JF. Successful restoration of protective immunity against measles, mumps, and rubella following MMR vaccination in adult hematopoietic cell transplant recipients. Transpl Infect Dis. 2023 Apr; 25(2):e14043.  View on PubMed
  6. Barreras H, Copsel SN, Bader CS, Ding Y, Wolf D, Cash C, Stacey CJ, Benjamin C, Seavey MM, Wolf J, Jasuja RR, Pfeiffer B, Hill GR, Komanduri KV, Jurecic R, Malek TR, Levy RB. Regulatory T Cell Amelioration of Graft-versus-Host Disease following Allogeneic/Xenogeneic Hematopoietic Stem Cell Transplantation Using Mobilized Mouse and Human Peripheral Blood Donors. Transplant Cell Ther. 2023 05; 29(5):341.e1-341.e9.  View on PubMed
  7. Nikiforow S, Frigault MJ, Frey NV, Gardner RA, Komanduri KV, Perales MA, Kebriaei P, Warkentin PI, Pasquini M, Aho JL, Levine BL, Heslop HE, Hlucky TL, Habucky K, Gharibo M, Jagasia M, Locke FL. Paving the Road for Chimeric Antigen Receptor T Cells: American Society for Transplantation and Cellular Therapy 80/20 Task Force Consensus on Challenges and Solutions to Improving Efficiency of Clinical Center Certification and Maintenance of Operations for Commercially Approved Immune Effector Cell Therapies. Transplant Cell Ther. 2023 04; 29(4):228-239.  View on PubMed
  8. Shah AM, Galor A, Mones K, Jean P, Komanduri KV, Wang TP. Conjunctival inflammation and dry eye symptoms at day 100 post-transplantation do not predict risk for chronic graft-versus-host disease. Taiwan J Ophthalmol. 2023 Jan-Mar; 13(1):43-48.  View on PubMed
  9. Zurko J, Ramdial J, Shadman M, Ahmed S, Szabo A, Iovino L, Tomas AA, Sauter C, Perales MA, Shah NN, Acharya UH, Jacobson C, Soiffer RJ, Wang T, Komanduri KV, Jaglowski S, Kittai AS, Denlinger N, Iqbal M, Kharfan-Dabaja MA, Ayala E, Chavez J, Jain M, Locke FL, Samara Y, Budde LE, Mei MG, Pia AD, Feldman T, Ahmed N, Jacobs R, Ghosh N, Dholaria B, Oluwole OO, Hess B, Hassan A, Kenkre VP, Reagan P, Awan F, Nieto Y, Hamadani M, Herrera AF. Allogeneic transplant following CAR T-cell therapy for large B-cell lymphoma. Haematologica. 2023 01 01; 108(1):98-109.  View on PubMed
  10. Shaw BE, Jimenez-Jimenez AM, Burns LJ, Logan BR, Khimani F, Shaffer BC, Shah NN, Mussetter A, Tang XY, McCarty JM, Alavi A, Farhadfar N, Jamieson K, Hardy NM, Choe H, Ambinder RF, Anasetti C, Perales MA, Spellman SR, Howard A, Komanduri KV, Luznik L, Norkin M, Pidala JA, Ratanatharathorn V, Confer DL, Devine SM, Horowitz MM, Bolaños-Meade J. Three-Year Outcomes in Recipients of Mismatched Unrelated Bone Marrow Donor Transplants Using Post-Transplantation Cyclophosphamide: Follow-Up from a National Marrow Donor Program-Sponsored Prospective Clinical Trial. Transplant Cell Ther. 2023 03; 29(3):208.e1-208.e6.  View on PubMed
  11. Liu H, Nuksani P, Rajagopalan M, Patil M, Komanduri K, Murphy B, Khuntia D, Beriwal S. Improvement in plan quality after Implementation of clinical goals in a large network of cancer centers. Med Dosim. 2023 Spring; 48(1):51-54.  View on PubMed
  12. Watson AN, Shah SA, Shalhoub SD, Piedra KM, Komanduri KV, Kwon D, Pereira DL. Melphalan on day -1 versus day -2 in patients with plasma cell disorders undergoing autologous stem cell transplant. J Oncol Pharm Pract. 2022 Oct 17; 10781552221125871.  View on PubMed
  13. Jimenez Jimenez A, Komanduri K, Brown S, Wang T, Pereira D, Goodman M, Beitinjaneh A, Lekakis L, Chinapen S, Devlin S, Ponce D, Sauter C, Perales MA, Shaffer BC. Improved GRFS after posttransplant cyclophosphamide-based vs ATG-based HLA-mismatched unrelated donor transplant. Blood Adv. 2022 08 09; 6(15):4491-4500.  View on PubMed
  14. Datta J, Bianchi A, De Castro Silva I, Deshpande NU, Cao LL, Mehra S, Singh S, Rafie C, Sun X, Chen X, Dai X, Colaprico A, Sharma P, Dosch AR, Pillai A, Hosein PJ, Nagathihalli NS, Komanduri KV, Wilson JM, Ban Y, Merchant NB. Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer. Oncogene. 2022 07; 41(28):3640-3654.  View on PubMed
  15. Jimenez Jimenez AM, De Lima M, Komanduri KV, Wang TP, Zhang MJ, Chen K, Abdel-Azim H, Abid MB, Aljurf M, Alkhateeb H, Assal A, Bacher U, Baron F, Battiwalla M, Beitinjaneh A, Bejanyan N, Bhatt VR, Byrne M, Cahn JY, Cairo M, Castillo P, Copelan E, DeFilipp Z, Perez MAD, Elsawy M, Gale RP, George B, Grunwald MR, Hildebrandt GC, Hogan WJ, Kanakry CG, Kansagra A, Kharfan-Dabaja MA, Khera N, Krem MM, Lazaryan A, Maakaron J, Martino R, McGuirk J, Michelis FV, Milone G, Mishra A, Murthy HS, Mussetti A, Nathan S, Nishihori T, Olsson RF, Palmisiano N, Patel S, Saad A, Seo S, Sharma A, Solh M, Verdonck LF, Wirk B, Yared JA, Litzow M, Kebriaei P, Hourigan CS, Saber W, Weisdorf D. Correction to: An adapted European LeukemiaNet genetic risk stratification for acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplant. A CIBMTR analysis. Bone Marrow Transplant. 2022 May; 57(5):852.  View on PubMed
  16. Wolf D, Barreras H, Copsel SN, Komanduri KV, Levy RB. Improved NK Cell Recovery Following Use of PTCy or Treg Expanded Donors in Experimental MHC-Matched Allogeneic HSCT. Transplant Cell Ther. 2022 06; 28(6):303.e1-303.e7.  View on PubMed
  17. Spiegel JY, Komanduri KV. Treating CAR-T relapses: check not checkmate. Blood. 2022 02 17; 139(7):955-957.  View on PubMed
  18. Camargo JF, Jabr R, Anderson AD, Lekakis L, Diaz-Paez M, Briski LM, Raja M, Morris MI, Komanduri KV, Pereira D. Successful Treatment of Disseminated Disease Due to Highly Resistant Aspergillus calidoustus with a Novel Antifungal Therapy. Antimicrob Agents Chemother. 2022 03 15; 66(3):e0220621.  View on PubMed
  19. Jimenez Jimenez AM, De Lima M, Komanduri KV, Wang TP, Zhang MJ, Chen K, Abdel-Azim H, Abid MB, Aljurf M, Alkhateeb H, Assal A, Bacher U, Baron F, Battiwalla M, Beitinjaneh A, Bejanyan N, Bhatt VR, Byrne M, Cahn JY, Cairo M, Castillo P, Copelan E, DeFilipp Z, Perez MAD, Elsawy M, Gale RP, George B, Grunwald MR, Hildebrandt GC, Hogan WJ, Kanakry CG, Kansagra A, Kharfan-Dabaja MA, Khera N, Krem MM, Lazaryan A, Maakaron J, Martino R, McGuirk J, Michelis FV, Milone G, Mishra A, Murthy HS, Mussetti A, Nathan S, Nishihori T, Olsson RF, Palmisiano N, Patel S, Saad A, Seo S, Sharma A, Solh M, Verdonck LF, Wirk B, Yared JA, Litzow M, Kebriaei P, Hourigan CS, Saber W, Weisdorf D. An adapted European LeukemiaNet genetic risk stratification for acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplant. A CIBMTR analysis. Bone Marrow Transplant. 2021 12; 56(12):3068-3077.  View on PubMed
  20. Chandorkar A, Anderson AD, Morris MI, Natori Y, Jimenez A, Komanduri KV, Camargo JF. Viral kinetics and outcomes of adenovirus viremia following allogeneic hematopoietic cell transplantation. Clin Transplant. 2021 12; 35(12):e14481.  View on PubMed

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