Research Summary

Johannes R. Kratz, M.D. is Director of Minimally Invasive and Robotic Thoracic Surgery and holds the Van Auken Endowed Chair in Thoracic Oncology. Kratz graduated magna cum laude from Harvard Medical School and holds a Masters in Philosophy from Stanford.

Kratz worked as research fellow in the Thoracic Oncology Lab from 2008-2011 where he played a pivotal role in the development of a prognostic assay for early-stage lung cancer patients. The novel assay was validated in an international clinical trial led by thoracic surgeons David M. Jablons, M.D. and Michael Mann, M.D. The assay better predicted risk of death in early-stage lung cancer patients versus conventional staging guidelines and later successfully identified Stage 1A lung cancer patients who had a very high likelihood of mortality after surgery. Kratz finished his clinical training as a clinical fellow in Thoracic Surgery at UCSF from 2014 - 2017.

Kratz has published numerous papers and has been the recipient of numerous awards and honors including the Partners Healthcare Resident/Fellow as Teacher Award, Willard M. Daggett Award, Edward Churchill Surgical Research Fellowship, Wyeth Scholarship of the American College of Surgeons, John E. Thayer Scholarship Award, Howard Hughes Medical Fellows Program Continued Support Award, Hellman Family Clinical-Translational Research Development Award, Howard Hughes Medical Student Research Fellowship, Michael DeBakey Research Scholarship, and designation as a Soma Weiss Scholar.

Research Funding

  • July 1, 2020 - June 30, 2022 - Immune Phenotypes of High-Risk Early Stage Lung Adenocarcinoma, Principal Investigator. Sponsor: American Association of Thoracic Surgery, Sponsor Award ID:
  • August 1, 2019 - July 31, 2021 - CoProject Pilot in Early-Stage Lung Cancer, Principal Investigator. Sponsor: Bakar ImmunoX Foundation, Sponsor Award ID:
  • June 3, 2020 - June 2, 2021 - COVID-19 Related Rapid Research Pilot Initiative, Principal Investigator. Sponsor: University of California, San Francisco, Sponsor Award ID:
  • October 19, 2019 - September 30, 2020 - Lung Cancer Tumor Immune Microenvironments, Principal Investigator. Sponsor: Helen Diller Family Comprehensive Cancer Center, Sponsor Award ID:

Education

Stanford University, Palo Alto, CA, B.A. (with Distinction), 06/1999, Philosophy
Stanford University, Palo Alto, CA, B.S. (with Honors with Distinction), 06/1999, Biological Sciences
Stanford University, Palo Alto, CA, M.A., 06/2000, Philosophy
Harvard Medical School, Boston, MA, M.D. (Magna cum laude), 06/2006
Massachusetts General Hospital, Boston, MA, Residency, 06/2014, General Surgery
University of California, San Francisco, CA, Post-Doctoral Research Fellowship, 06/2011, Thoracic Oncology
University of California, San Francisco, CA, Fellowship, 06/2017, Cardiothoracic Surgery

Honors & Awards

  • 2005
    Soma Weiss Scholar Award, Harvard Medical School
  • 2006
    John E. Thayer Scholarship Award, Harvard Medical School
  • 2010
    Willard M. Daggett Award, Massachusetts General Hospital
  • 2011
    President's Conference Selection, World Conference on Lung Cancer, International Association for the Study of Lung Cancer
  • 2012
    First Place, Oral Presentation, Harvard Medical School Surgery Research Conference, Harvard Medical School
  • 2012
    Partners HealthCare Resident/Fellow as Teacher Award (awarded to one resident among all specialties across all eleven Partners HealthCare hospitals), Partners HealthCare
  • 2017
    UCSF Health Exceptional Physician Award (awarded for Professionalism, Respect, Integrity, Diversity and Excellence), UCSF
  • 2018
    Van Auken Endowed Chair in Thoracic Oncology, University of California, San Francisco
  • 2019
    Hellman Family Clinical-Translational Research Development Award, Bakar ImmunoX Initiative
  • 2019
    Haile T. Debas Academy of Medical Educators Excellence in Teaching Award (awarded for Medical Student education), UCSF
  • 2019
    Michael DeBakey Research Scholarship (awarded to a single North American surgeon committed to pursuing an academic career in cardiothoracic surgery)

Selected Publications

  1. Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.  View on PubMed
  2. Calixto-Hope G. Lucas, Johannes R. Kratz, Anatoly Urisman Pulmonary Embolus of Benign Liver Tissue Following Partial Hepatectomy.  View on PubMed
  3. Haro GJ, Sheu B, Marcus SG, Sarin A, Campbell L, Jablons DM, Kratz JR Perioperative Lung Resection Outcomes After Implementation of a Multidisciplinary, Evidence-based Thoracic ERAS Program.  View on PubMed
  4. Haro GJ, Sheu B, Cook NR, Woodard GA, Mann MJ, Kratz JR Comparison of Conventional TNM and Novel TNMB Staging Systems for Non-Small Cell Lung Cancer.  View on PubMed
  5. Greg J. Haro, Fang Yu Sheu, Stanley J. Rogers, David M. Jablons, Johannes R. Kratz Esophagectomy Outcomes after Implementation of an Enhanced Recovery after Surgery Program.  View on PubMed
  6. G. Woodard, V. Ding, I. Kim, K. Jones, G. Chavez, G. Haro, J. Kratz, M. Mann, J. Rotow, C. Blakely, D. Jablons MA06.09 Timing of Driver Mutation Development and the Genetic Evolution of Semi-Solid Lung Nodules into Early NSCLC.  View on PubMed
  7. J. Rotow, A. Urisman, C. Mccoach, T. Jahan, T. Bivona, K. Jones, A. Gupta, H. Do, J. Riess, D. Aisner, R. Doebele, D. Jablons, J. Kratz, C. Blakely P1.14-58 A Phase II Study to Evaluate Neoadjuvant Osimertinib for Surgically Resectable, EGFR-Mutant Non-Small Cell Lung Cancer.  View on PubMed
  8. Jiang L, Tolani B, Yeh CC, Fan Y, Reza JA, Horvai AE, Xia E, Kratz JR, Jablons DM, Mann MJ Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma.  View on PubMed
  9. Kratz JR, Haro GJ, Cook NR, He J, Van Den Eeden SK, Woodard GA, Gubens MA, Jahan TM, Jones KD, Kim IJ, He B, Jablons DM, Mann MJ Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging.  View on PubMed
  10. Lancaster EM, Jablons D, Kratz JR Applications of Next-Generation Sequencing in Neoantigen Prediction and Cancer Vaccine Development.  View on PubMed
  11. Haro GJ, Seeley EJ, Jablons DM, Kratz JR Central Airway Obstruction Due to Tracheal Glomus Tumor.  View on PubMed
  12. Ramirez JL, Kratz JR, Wieselthaler GM Giant right coronary artery aneurysm presenting as cardiac tamponade.  View on PubMed
  13. G. Woodard, S. Wang, J. Kratz, G. Haro, M. Gubens, C. Blakely, T. Jahan, K. Jones, M. Mann, D. Jablons P2.16-12 Expanded Data Confirm Molecular Testing Identifies Lung Adenocarcinoma Patients, Including Stage IA, Who Benefit from Adjuvant Chemotherapy.  View on PubMed
  14. G. Haro, J. Kratz, N. Cook, J. He, S. Van Den Eeden, G. Woodard, M. Gubens, T. Jahan, K. Jones, I. Kim, B. He, D. Jablons, M. Mann P3.03-24 Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging.  View on PubMed
  15. Greg J. Haro, Johannes R. Kratz, David M. Jablons, Michael J. Mann, Jasleen Kukreja Propensity Matched Analysis of Perioperative Outcomes in Robotic-Assisted Thoracic Surgery, Video Assisted Thoracic Surgery, and Open Lung Resections.  View on PubMed
  16. Ramirez J, Wieselthaler G, Kratz J Intraoperative identification and treatment of a giant right coronary artery aneurysm.  View on PubMed
  17. Ramirez JL, Urisman A, Kukreja J, Kratz JR Surgical Management of Pulmonary Mucormycosis in Third-Trimester Pregnancy.  View on PubMed
  18. Woodard GA, Wang SX, Kratz JR, Zoon-Besselink CT, Chiang CY, Gubens MA, Jahan TM, Blakely CM, Jones KD, Mann MJ, Jablons DM Adjuvant Chemotherapy Guided by Molecular Profiling and Improved Outcomes in Early Stage, Non-Small-Cell Lung Cancer.  View on PubMed
  19. Kratz JR, Woodard G, Jablons DM Management of Lung Cancer Invading the Superior Sulcus.  View on PubMed
  20. Gavitt Woodard, Jane Crockard, Clara Zoon-Besselink, Johannes Kratz, Matthew Gubens, Thierry Jahan, Collin Blakely, Kirk Jones, Michael Mann, David Jablons OA19.06 Adjuvant Chemotherapy Decisions Based on Molecular Risk Status Improves Outcomes in Early Stage, Non-Small Cell Lung Cancer.  View on PubMed

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