Ana Velázquez Mañana, MD, MSc

Assistant Clinical Professor, Medicine, UCSF

Cancer Center Program Membership

Cancer Control

Research Summary

Dr. Ana Velázquez Mañana, MD, MSc, is an Assistant Professor of Medicine in the UCSF Division of Hematology/Oncology at Zuckerberg San Francisco General and a thoracic oncologist at the UCSF Helen Diller Family Comprehensive Cancer Center. As a Latina and proud Puerto Rican, she is a passionate advocate for diversity and inclusion. Dr. Velazquez previously served as Assistant Director of Diversity, Equity, Inclusion, and Accessibility for Trainees of the UCSF Helen Diller Family Comprehensive Cancer Center and co-chaired the UCSF Department of Medicine Fellowship Diversity Committee. Her research, advocacy, and education efforts are focused on promoting and advancing health equity and workforce diversity.

Dr. Velazquez completed her MD at the University of Puerto Rico School of Medicine, Master of Biomedical Science at Mayo Clinic Graduate School, and Internal Medicine residency at Mount Sinai Beth Israel, where she was also a Chief Resident. She joined UCSF in 2018 to complete her clinical fellowship in Medical Oncology and a postdoctoral research fellowship at the National Clinician Scholars Program. Dr. Velazquez is a scientist scholar affiliated with the UCSF Center for Aging in Diverse Communities (CADC) and the UCSF Multiethnic Health Equity Research Center. She has been selected as a 2022 UCSF John A. Watson Faculty Scholars.

Dr. Velazquez’s research portfolio centers on the use of health services and cancer disparities research to decrease barriers to clinical trial participation, improve the quality of care delivered to underserved and racial minority patients with cancer, and evaluate the unmet social and supportive care needs of patients with lung cancer from vulnerable backgrounds. Her goals are to develop interventions that improve healthcare access and cancer care delivery for vulnerable populations. Dr. Velazquez’s research is supported by the American Association for Cancer Research, Conquer Cancer Foundation of ASCO, Stavros Niarchos Foundation, LUNGevity, National Institute on Aging, National Cancer Institute, and pilot funds from the Helen Diller Family Comprehensive Cancer Center.

 

Research Funding:

AACR Career Development Award to Further Diversity, Equity, and Inclusion in Clinical Cancer Research Title: Lung Cancer Equity Through Screening for Social Needs: The LESSON Study Role: Principal Investigator

12/2022 – 11/2025

2022 LUNGevity Health Equity and Inclusiveness Junior Investigator Research Award Title: Lung cancer Equity Through Social needs SCREENing (LETS SCREEN) Role: Principal Investigator

 

11/2022 – 10/2024

Conquer Cancer – Women Who Conquer Cancer Young Investigator Award in Recognition of an Outstanding Latina Researcher   Title: Longitudinal Evaluation of Health-Related Social Needs in Advanced Lung Cancer

Role: Principal Investigator

07/2022 – 06/2023

Education

  • University of Puerto Rico; Mayaguez, PR, BS, 06/2009, Pre-Medicine
  • University of Puerto Rico School of Medicine; San Juan, PR, MD, 06/2014, Doctor in Medicine
  • Mayo Graduate School; Rochester, MN, MSc, 06/2015, Master’s in Science
  • Icahn School of Medicine Mount Sinai Beth Israel; New York, NY, 06/2017, Internal Medicine Residency
  • Icahn School of Medicine Mount Sinai Beth Israel, New York, NY, 06/2018, Chief Residency, Fellow in Medical Education
  • University of California, San Francisco, CA, Medical Oncology Fellowship
  • University of California, San Francisco, CA, National Clinician Scholar

Honors & Awards

  • 2022
    Conquer Cancer Foundation Merit Award, ASCO Quality Care Symposium
  • 2022
    University of California, San Francisco John A. Watson Scholar
  • 2021
    Women Leaders in Oncology LEAD Rising Star
  • 2021
    Conquer Cancer Foundation Merit Award, ASCO Annual Meeting
  • 2021
    Conquer Cancer Foundation Merit Award, ASCO Quality Care Symposium
  • 2021
    American Association for Cancer Research Student and Early Career Investigator Scholarship
  • 2020
    University of California, San Francisco UCSF Health Exceptional Physician Award
  • 2020
    American Association for Cancer Research Scholar-in-Training Award, 13th AACR Conference on the Science of Cancer Health Disparities
  • 2020
    University of California, San Francisco Center for Aging in Diverse Communities Scientists Program (NIA P30AG015272)
  • 2020
    Conquer Cancer Foundation Merit Award, ASCO Annual Meeting
  • 2020
    Advancing the Science of Cancer in Latinos Travel Scholarship
  • 2019
    Honor Society of Phi Kappa Phi Love of Learning Award
  • 2019
    American Association for Cancer Research Scholar-in-Training Award, 12th AACR Conference on the Science of Cancer Health Disparities
  • 2019
    Conquer Cancer Foundation Merit Award, ASCO Quality Care Symposium
  • 2019
    Association of Northern California Oncologists ASCO Annual Meeting Travel Award
  • 2017
    Icahn School of Medicine at Mount Sinai Beth Israel Department of Medicine Ira B. Cohen Award
  • 2016
    NIDDK/NHMA Academic Career Development Workshop and Travel Award

Selected Publications

  1. Butler B, Velazquez AI, Trejo E, Huppert LA, Hsu G, Babik JM, Santhosh L How do Internal Medicine Residents from Different Backgrounds Make Subspecialty Career Choices? A Qualitative Analysis.  View on PubMed
  2. Leite LF, da Conceição LD, Saldanha EF, Menezes S, de Melo AC, Borea R, Corassa M, Manana AV, Cardona AF, Arrieta O, Rios-Garcia E, Corrales L, Rolfo C, Cordeiro de Lima VC Cancer Incidence and Mortality Estimates in Latin America and the Caribbean: A Systematic Analysis of the GLOBOCAN 2022.  View on PubMed
  3. Florez N, Patel S, Wakelee HA, Rotow J, Shum E, Sands J, Salgia R, Hirsch FR, Peters S, Sabari J, Husain H, Bazhenova L, Massarelli E, Backhus LM, Lee P, Herbst RS, Bestvina C, Higgins K, Desai A, Dietrich M, Keshava HB, Halmos B, Gandara DR, Riess JW, Velázquez AI, Sibley A, Shields M, Sen T, Kim ES Clinical strategies for lung cancer management: Recommendations from the Bridging the Gaps Lung Cancer Consensus Conference 2024.  View on PubMed
  4. Nassar AH, Kim C, Adeyelu T, Bou Farhat E, Abushukair H, Rakaee M, Matteson K, Lau SF, Takabe Y, Ocejo A, Ardeshir-Larijani F, Leal T, Ramalingam S, Alam S, Gray JE, Hicks J, Kaldas D, Baena J, Berjaga MZ, Nana FA, Grohe C, Leuders H, Citarella F, Cortellini A, Mingo EC, Pancirer D, Das M, Ellis-Caleo TJ, Cheung JM, Lin JJ, Watson AS, Camidge DR, Sridhar A, Parikh K, Crowley F, Marron TU, Aggarwal V, Ahmed M, Sankar K, Kawtharany H, Zhang J, Owen DH, Li M, Nagasaka M, Pinato DJ, Awosika N, Alhamad K, Puri S, Zaman U, Gupta DM, Lau C, Khan H, Liauw J, Velazquez AI, Brown T, Moliner L, Mosteiro M, Rocha P, Evans M, Vanderwalde A, Elliott A, Nieva J, Lopes G, Ma PC, Borghaei H, Lee M, Young L, Aljumaily R, Mirza H, Kwiatkowski DJ, Herbst RS, Flavell RA, Naqash AR, Chiang AC Integrated molecular and clinical characterization of pulmonary large cell neuroendocrine carcinoma.  View on PubMed
  5. Reuss JE, Kuruvilla S, Ismaila N, Azar IH, Feldman J, Furuya N, Wheatley-Price P, Roof L, Velazquez AI, Wang Y, Leighl NB Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2025.1.  View on PubMed
  6. Hernández-Marrero J, Rivera-Santiago T, Bournigal-Feliciano M, Colón-López V, Velázquez AI, Salmerón J, Palefsky JM, Ortiz AP, Soto-Salgado M Perception of healthcare professionals about the knowledge of people living with HIV regarding clinical trials for HIV-related cancers.  View on PubMed
  7. Florez N, Kiel L, Kaufman R, LoPiccolo J, Ricciuti B, Morabito A, Fakorede O, Mantz C, Olazagasti C, Swami N, Kanan D, Alder L, Sridhar A, Bergerot CD, Bye B, Velazquez AI, Shaw AT Young lung cancer: from diagnosis to survivorship.  View on PubMed
  8. Castañeda-Avila MA, Santiago-Rodríguez EJ, Rodríguez-Cintrón W, Olazagasti C, Flores EJ, Rodríguez E, Velázquez Mañana AI, Otero-Domínguez Y, Núñez ER Lung Cancer Screening Eligibility, Uptake, and Adherence in Puerto Rico, 2022.  View on PubMed
  9. Olazagasti C, Celi CV, Mahtani A, Velazquez AI, Kiel L, Sridhar A, Horiguchi M, Gonzalez M, Bernabe C, Abioye O, Dizman N, Florez N. Going Back Home: Understanding the Challenges and Discrimination of Early and Mid-Career International and Puerto Rican Medical Graduates in Oncology Fields in the United States. JCO Glob Oncol. 2025 Mar; 11:e2400513.  View on PubMed
  10. Hum CE, Velazquez AI, Marshall AL. Gender Equity Education in Oncology: A Survey Study of Hematology-Oncology Fellowship Program Directors. J Cancer Educ. 2025 Feb 18.  View on PubMed
  11. Lee HJ, Boscardin J, Walter LC, Smith AK, Cohen HJ, Giri S, Williams GR, Presley CJ, Singhal S, Huang LW, Velazquez AI, Gubens MA, Blakely CM, Mulvey CK, Cheng ML, Sakoda LC, Kushi LH, Quesenberry C, Liu R, Fleszar-Pavlovic S, Eskandar C, Cutler E, Mercurio AM, Wong ML. Associations of frailty with survival, hospitalization, functional decline, and toxicity among older adults with advanced non-small cell lung cancer. Oncologist. 2024 Dec 09.  View on PubMed
  12. Singhal S, Walter LC, Smith AK, Boscardin WJ, Shi Y, Cohen HJ, Presley CJ, Kushi LH, Giri S, Magnuson A, Williams GR, Velazquez AI, Lee HJ, Sakoda LC, Quesenberry CP, Falvey JR, Van Dyk KM, Wong ML. Function, cognition, and quality of life among older adults with lung cancer who live alone: A prospective cohort study. J Geriatr Oncol. 2024 11; 15(8):102068.  View on PubMed
  13. Nassar AH, Jayakrishnan R, Feng J, Shepherd F, Adib E, Cheung JM, Lin JJ, Liu Y, Lin SH, Parikh K, Sridhar A, Shakya P, Dilling TJ, Kaldas D, Gray JE, Lobachov A, Bar J, Luders H, Grohe C, Gupta S, Leal T, Fitzgerald B, Crowley F, Fujiwara Y, Marron TU, Wilgucki M, Reuss J, Chen L, Sankar K, Aredo JV, Neal JW, Wakelee HA, Thummalapalli R, Yu H, Whitaker R, Velazquez A, Ragavan M, Cortellini A, Kwiatkowski DJ, Naqash AR, Goldberg SB, Kim SY. Consolidation ALK Tyrosine Kinase Inhibitors Versus Durvalumab or Observation After Chemoradiation in Unresectable Stage III ALK-Positive NSCLC. J Thorac Oncol. 2025 Jan; 20(1):109-118.  View on PubMed
  14. Chan A, Eng L, Jiang C, Dagsi M, Ke Y, Tanay M, Bergerot C, Dixit N, Gutiérrez AC, Velazquez AI, Islami F, Soto-Perez-de-Celis E. Global disparities in cancer supportive care: An international survey. Cancer Med. 2024 Sep; 13(17):e70234.  View on PubMed
  15. Chan A, Ke Y, Tanay M, Dagsi M, Bergerot C, Dixit N, Eng L, Cardeña Gutiérrez A, Jiang C, Velázquez AI, Islami F, Soto-Perez-de-Celis E. Financial Toxicity in Cancer Supportive Care: An International Survey. JCO Glob Oncol. 2024 Jul; 10:e2400043.  View on PubMed
  16. Owen DH, Ismaila N, Freeman-Daily J, Roof L, Singh N, Velazquez AI, Leighl NB. Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2024.1. J Clin Oncol. 2024 Jul 10; 42(20):e44-e59.  View on PubMed
  17. Trejo E, Velazquez AI, Castillo E, Couey P, Cicerelli B, McBride R, Burke NJ, Dixit N. Acceptability and Feasibility of Survivorship Group Medical Visits for Breast Cancer Survivors in a Safety Net Hospital. J Cancer Educ. 2024 Aug; 39(4):445-454.  View on PubMed
  18. Litt HK, Greenstreet-Akman E, Trejo E, Florez N, Velazquez AI. Quality and Accessibility of Liquid Biopsy Information. JAMA Netw Open. 2024 05 01; 7(5):e2410171.  View on PubMed
  19. Kumar A, Ragavan M, Velazquez AI, Zeng S, Wong ML. Receipt of financial assistance for oral targeted therapy among older adults with advanced non-small cell lung cancer: A prospective cohort study. J Geriatr Oncol. 2024 06; 15(5):101746.  View on PubMed
  20. Soto-Perez-de-Celis E, Ke Y, Tanay M, Dagsi M, Bergerot C, Dixit N, Eng L, Cardeña-Gutiérrez A, Jiang C, Velazquez AI, Islami F, Chan A. Equity, diversity, and inclusion in the Multinational Association for Supportive Care in Cancer: a global membership survey. Support Care Cancer. 2024 Mar 04; 32(3):205.  View on PubMed

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