Research Summary

Dr. Kavita K. Mishra is an internationally renowned expert radiation oncologist focused on the treatment of uveal melanomas with proton beam radiotherapy as well as plaque brachytherapy. She earned her undergraduate degree in Biology at Harvard University, followed by her medical degree at the UCSF School of Medicine. She then completed a masters degree at the Harvard School of Public Health. Dr. Mishra finished her residency in radiation oncology at the UCSF Medical Center and thereafter joined the faculty at UCSF.

Dr. Mishra specializes in the use of proton beam radiation and plaque brachytherapy to treat malignant and benign conditions of the eye. Dr. Mishra believes in a multidisciplinary approach to ocular oncology care with the aim to provide the most efficacious and individualized therapy for her patients. She is active in the national and international ocular oncology community, is the Co-Chair of PTCOG Ocular (Particle Therapy Co-Operative Group) - the largest collection of proton beam ocular radiation therapy institutions, and has multiple significant research publications and oral presentations globally in her areas of expertise.

Her current research protocols are focused on the clinical outcomes of uveal melanoma patients, particularly with respect to tumor control, preservation of the eye, and quality of life issues. She hopes to continue using a unified, team-oriented approach to maintain excellent outcomes for patients undergoing modern proton beam, plaque therapy, and external beam radiation techniques for ocular malignancies.

Research Funding

  • January 20, 2021 - January 20, 2021 - Millimeter scale particle dosimeter for cancer radiotherapy, Co-Investigator. Sponsor: , Sponsor Award ID:
  • January 20, 2021 - January 20, 2021 - Long-Term Investigation of Proton Beam Radiation Therapy, Helium Ion, and Plaque Therapy Techniques for Treatment of Uveal Melanoma and Other Ocular Tumors, Principal Investigator. Sponsor: , Sponsor Award ID:
  • January 26, 2021 - January 26, 2021 - Long-Term Investigation of Proton Beam Radiation Therapy, Helium Ion, and Plaque Therapy Techniques for Treatment of Uveal Melanoma and Other Ocular Tumors, Principal Investigator. Sponsor: , Sponsor Award ID:
  • January 26, 2021 - January 26, 2021 - Millimeter scale particle dosimeter for cancer radiotherapy, Co-Investigator. Sponsor: , Sponsor Award ID:

Education

Residency, 2008 - Radiation Oncology, University of California, San Francisco
M.P.H., 2003 - Masters in Public Health, Harvard School of Public Health
M.D., 2002 - Medicine, University of California, San Francisco
A.B., 1998 - Biology, Harvard University
Residency, 2008 - Radiation Oncology, University of California, San Francisco
M.P.H., 2003 - Masters in Public Health, Harvard School of Public Health
M.D., 2002 - Medicine, University of California, San Francisco
A.B., 1998 - Biology, Harvard University
Residency, 2008 - Radiation Oncology, University of California, San Francisco
M.P.H., 2003 - Masters in Public Health, Harvard School of Public Health
M.D., 2002 - Medicine, University of California, San Francisco
A.B., 1998 - Biology, Harvard University
Residency, 2008 - Radiation Oncology, University of California, San Francisco
M.P.H., 2003 - Masters in Public Health, Harvard School of Public Health
M.D., 2002 - Medicine, University of California, San Francisco
A.B., 1998 - Biology, Harvard University
Residency, 2008 - Radiation Oncology, University of California, San Francisco
M.P.H., 2003 - Masters in Public Health, Harvard School of Public Health
M.D., 2002 - Medicine, University of California, San Francisco
A.B., 1998 - Biology, Harvard University

Honors & Awards

  • Faculty Scholar, Osher Center for Integrative Medicine, University of California San Francisco, 2020
  • Highest ranked scientific abstract, Particle Therapy Co-Operative Group, 2015
  • RSNA Roentgen Resident/Fellow Research Award, University of California San Francisco, 2008
  • Class Speaker, UCSF School of Medicine Commencement, University of California San Francisco, 2002
  • Rainer Scholarship for International Health Research, University of California San Francisco, 1999
  • Harvard College Scholar, Dean's List, Harvard University, 1998
  • First Class Marshal, Harvard Class of 1998, Harvard University, 1998

Selected Publications

  1. Lee K, Scholey J, Norman EB, Daftari IK, Mishra KK, Faddegon BA, Maharbiz MM, Anwar M A Millimeter-scale Single Charged Particle Dosimeter for Cancer Radiotherapy.  View on PubMed
  2. Mishra KK, Scholey JE, Daftari IK, Afshar A, Tsai T, Park S, Quivey JM, Char DH Oral isotretinoin and topical retinoid use in a series of young patients with ocular melanoma.  View on PubMed
  3. Mishra KK, Afshar A, Thariat J, Shih HA, Scholey JE, Daftari IK, Kacperek A, Pica A, Hrbacek J, Dendale R, Mazal A, Heufelder J, Char DH, Sauerwein WAG, Weber DC, Damato BE Practice Considerations for Proton Beam Radiation Therapy of Uveal Melanoma During the Coronavirus Disease Pandemic: Particle Therapy Co-Operative Group Ocular Experience.  View on PubMed
  4. Mukkamala LK, Mishra K, Daftari I, Moshiri A, Park SS Phase I/II randomized study of proton beam with anti-VEGF for exudative age-related macular degeneration: long-term results.  View on PubMed
  5. Lu JE, Welch RJ, Mishra KK, Daftari IK, Park SS Ultrasonography and transillumination for uveal melanoma localisation in proton beam treatment planning.  View on PubMed
  6. Haas-Kogan D, Indelicato D, Paganetti H, Esiashvili N, Mahajan A, Yock T, Flampouri S, MacDonald S, Fouladi M, Stephen K, Kalapurakal J, Terezakis S, Kooy H, Grosshans D, Makrigiorgos M, Mishra K, Poussaint TY, Cohen K, Fitzgerald T, Gondi V, Liu A, Michalski J, Mirkovic D, Mohan R, Perkins S, Wong K, Vikram B, Buchsbaum J, Kun L National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury.  View on PubMed
  7. Daftari IK, Quivey JM, Chang JS, Mishra KK Technical Note: Feasibility study of titanium markers in choroidal melanoma localization for proton beam radiation therapy.  View on PubMed
  8. Osmanovic S, Moisseiev E, Mishra KK, Daftari I, Moshiri A, Morse L, Park SS Phase I/II Randomized Study of Proton Beam with Anti-Vascular Endothelial Growth Factor for Exudative Age-Related Macular Degeneration: One-Year Results.  View on PubMed
  9. Polishchuk AL, Mishra KK, Weinberg V, Daftari IK, Nguyen JM, Cole TB, Quivey JM, Phillips TL, Char DH Temporal Evolution and Dose-Volume Histogram Predictors of Visual Acuity After Proton Beam Radiation Therapy of Uveal Melanoma.  View on PubMed
  10. Mishra KK, Daftari IK Proton therapy for the management of uveal melanoma and other ocular tumors.  View on PubMed
  11. Mishra KK, Chiu-Tsao ST, Orton CG Point/Counterpoint. Particle therapy is ideal for the treatment of ocular melanomas.  View on PubMed
  12. Hrbacek J, Mishra KK, Kacperek A, Dendale R, Nauraye C, Auger M, Herault J, Daftari IK, Trofimov AV, Shih HA, Chen YE, Denker A, Heufelder J, Horwacik T, Swakon J, Hoehr C, Duzenli C, Pica A, Goudjil F, Mazal A, Thariat J, Weber DC Practice Patterns Analysis of Ocular Proton Therapy Centers: The International OPTIC Survey.  View on PubMed
  13. Roach M, Schulte R, Mishra K, Faddegon B, Barani I, Lazar A, Blakely EA New Clinical and Research Programs in Particle Beam Radiation Therapy: The University of California San Francisco Perspective.  View on PubMed
  14. Mishra KK, Quivey JM, Daftari IK, Weinberg V, Castro JR, Phillips TL, Char DH In Reply to Kamrava and McCannel.  View on PubMed
  15. Mishra KK, Quivey JM, Daftari IK, Weinberg V, Cole TB, Patel K, Castro JR, Phillips TL, Char DH Long-term Results of the UCSF-LBNL Randomized Trial: Charged Particle With Helium Ion Versus Iodine-125 Plaque Therapy for Choroidal and Ciliary Body Melanoma.  View on PubMed
  16. Seider MI, Stewart PJ, Mishra KK, Damato BE Uveal melanoma gene expression profile test result provided for uveal metastasis.  View on PubMed
  17. Mishra KK, Daftari IK, Weinberg V, Cole T, Quivey JM, Castro JR, Phillips TL, Char DH Risk factors for neovascular glaucoma after proton beam therapy of uveal melanoma: a detailed analysis of tumor and dose-volume parameters.  View on PubMed
  18. Chappell MC, Char DH, Cole TB, Harbour JW, Mishra K, Weinberg VK, Phillips TL Uveal melanoma: molecular pattern, clinical features, and radiation response.  View on PubMed
  19. Daftari IK, Mishra KK, O'Brien JM, Tsai T, Park SS, Sheen M, Phillips TL Fundus image fusion in EYEPLAN software: an evaluation of a novel technique for ocular melanoma radiation treatment planning.  View on PubMed
  20. Mishra KK, Squire S, Lamborn K, Banerjee A, Gupta N, Wara WM, Prados MD, Berger MS, Haas-Kogan DA Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update.  View on PubMed

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