Mary C. Nakamura, MD
Professor, Department of Medicine, UCSF
I am a clinical rheumatologist who has done basic research in the area of innate immune receptors, myeloid and natural killer cells for the past 29 years. For the last 20 years we have focused much of our work on the role of innate immune receptors on osteoclasts and innate immune regulation of normal and pathological bone turnover. We were one of the early groups focusing our research in the area of osteoimmunology and one of the first to identify the role of innate receptors in osteoclast differentiation and function. Our current research interests continue to primarily focus on osteoclasts and macrophage in arthritis, bone repair and turnover. Our studies of myeloid cells and bone repair have led us to also examine the roles of myeloid cells in tissue repair more broadly involving studies of brain and cardiac injury and ischemia.
I am on the organizing committee for the 8th International Osteoimmunology meeting (2022) and was the lead organizer for the 7th (2018), previously served on the scientific advisory committee for the Rheumatology Research Foundation and completed a term as a regular member of the NIH study section: Skeletal Biology Development and Disease (SBDD). I am currently Director of PREMIER (Precision Medicine in Rheumatology, an NIH funded P30 center) at UCSF. Our PREMIER Cores focus on Clinical Informatics, Genomic Technology (particularly single cell transcriptomics) and Integrative Bioinformatics. I am experienced in basic and translational research. My ongoing research collaborations with rheumatology, immunology, endocrinology, orthopedics and bone biology investigators uniquely position me to participate in and support research in innate immunity, osteoimmunology and translational studies in rheumatology. Recently, I have been participating in clinical care and translational research regarding patients with immune related adverse events due to cnacer immunotherapy. am an experienced mentor and am Director of the mentoring program for rheumatology fellows in our division and assist fellows both within and outside our division in the development of their individual development plans and career advancement.
Swarthmore College, Swarthmore, PA, B.A., 1981, Biology
Yale University School of Medicine, New Haven, CT, M.D., cum laude, 1986, Medicine
Intern and resident, Department of Internal Medicine, UCSF, San Francisco, CA, 1986-1989
Rheumatology Fellow, Div. Rheumatology, Johns Hopkins U., Baltimore, MD, 1990-1991
Rheumatology Fellow, Div. Rheumatology, UCSF, San Francisco, CA, 1991-1994