University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Pratik Mukherjee, MD, PhD

Pratik Mukherjee, MD, PhD

Assistant Professor, Department of Radiology, UCSF

Cancer Center Program Memberships

Affiliate Member

Research Summary

Pratik Mukherjee, MD, PhD, is a Professor in Residence in the Department Radiology and Biomedical Imaging, Bioengineering, and he is an attending neuroradiologist at the University of California, San Francisco. He is the Director of the Center for Imaging of Neurodegenerative Disease (CIND) based at the San Francisco VA Medical Center. He also directs the Neural Connectivity Laboratory (NCL) at UCSF China Basin.

Dr. Mukherjee received his PhD in Neuroscience from Rockefeller University, New York in 1994 and his MD from Cornell University, New York, in 1995. He completed his internship in Internal Medicine at New York Hospital - Cornell Medical Center, followed by a residency in Radiology and fellowship in Neuroradiology at Washington University Medical Center in St. Louis, Missouri, completed in 2002.

Dr. Mukherjee’s primary clinical research is the study of neurodevelopmental disorders and traumatic brain injury (TBI) using advanced MRI. His research has been focused on technical development, neuroscience and clinical applications of advanced imaging methods for mapping structure and function of the human brain, especially diffusion MRI, which is a popular technique for assessing the development and integrity of white matter and for mapping axonal fiber pathways.

Dr. Mukherjee has served as Principal Investigator or Co-Principal Investigator for several NIH grants. His work has also been funded by grants from the Dept. of Defense, the Simons Foundation, McDonnell Foundation, Dana Foundation, Wallace Research Foundation, GE Healthcare and the GE-NFL Head Health Initiative. He has published over 80 peer-reviewed papers.

Expertise:

Radiology, Neuroradiology, Pediatric Neuroradiology, Cognitive Neuroscience, Computational Neuroscience

Specialty:

Neuroradiology, traumatic brain injury (TBI), neurodevelopmental disorders

Professional Interests:

Brain development, computational neuroscience, connectomics, diffusion tensor imaging (DTI), epilepsy, functional MRI (fMRI), machine learning, magnetoencephalography (MEG), pediatric neuroradiology, traumatic brain injury (TBI), ultra-high field MRI, white matter tractography

Education and Training:

• Medical School: Cornell University, New York - Medicine

• Internship: New York Cornell Medical Center - Internal Medicine

• Residency: Washington University of Medical Center, St. Louis, Missouri - Radiology

• Fellowship: Washington University Medical Center, St. Louis, Missouri - Neuroradiology

• Doctor of Philosophy: Rockefeller University, New York - Neuroscience

• National Board of Medical Examiners Certificate

• American Board of Radiology Certificate

• Missouri Medical License

• California Medical License

• American Board of Radiology Certificate of Added Qualification Neuroradiology

Education

Yale University, New Haven, CT, B.A., 1988, Computer Science & Psychology
Rockefeller Univ., New York, NY, Ph.D., 1994, Neuroscience
Cornell University, New York, NY, M.D., 1995, Medicine


Professional Experience

  • 1995-1996
    Internal Medicine Internship, New York Hospital - Cornell Medical Center, New York, NY
  • 1996-2000
    Radiology Residency, Washington University Medical Center, St. Louis, MO
  • 2000-2002
    Neuroradiology Fellowship, Washington University Medical Center, St. Louis, MO
  • 2002-present
    Assistant Professor, University of California, San Francisco, CA

Honors & Awards

  • 1988-95
    Medical Scientist Training Program Grant, National Institutes of Health
  • 1994
    S. Koide Memorial Fellowship, Rockefeller University
  • 1999
    Roentgen Resident/Fellow Research Award, Radiological Society of North America
  • 2001
    Berlex/ASNR Award in Basic Science Research, American Society of Neuroradiology

Selected Publications

  1. Hinkley LBN, Dale C, Luks TL, Findlay AM, Bukshpun P, Pojman N, Thieu T, Chung WK, Berman J, Roberts TPL, Mukherjee P, Sherr EH, Nagarajan SS. Sensorimotor cortical oscillations during movement preparation in 16p11.2 deletion carriers. J Neurosci. 2019 Jul 03.
    View on PubMed
  2. Nelson LD, Temkin NR, Dikmen S, Barber J, Giacino JT, Yuh E, Levin HS, McCrea MA, Stein MB, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT. Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study. JAMA Neurol. 2019 Jun 03.
    View on PubMed
  3. Mallott JM, Palacios EM, Maruta J, Ghajar J, Mukherjee P. Disrupted White Matter Microstructure of the Cerebellar Peduncles in Scholastic Athletes After Concussion. Front Neurol. 2019; 10:518.
    View on PubMed
  4. Payabvash S, Palacios EM, Owen JP, Wang MB, Tavassoli T, Gerdes M, Brandes-Aitken A, Marco EJ, Mukherjee P. Diffusion tensor tractography in children with sensory processing disorder: Potentials for devising machine learning classifiers. Neuroimage Clin. 2019 Apr 24; 23:101831.
    View on PubMed
  5. Yue JK, Levin HS, Suen CG, Morrissey MR, Runyon SJ, Winkler EA, Puffer RC, Deng H, Robinson CK, Rick JW, Phelps RRL, Sharma S, Taylor SR, Vassar MJ, Cnossen MC, Lingsma HF, Gardner RC, Temkin NR, Barber J, Dikmen SS, Yuh EL, Mukherjee P, Stein MB, Cage TA, Valadka AB, Okonkwo DO, Manley GT. Age and sex-mediated differences in six-month outcomes after mild traumatic brain injury in young adults: a TRACK-TBI study. Neurol Res. 2019 Jul; 41(7):609-623.
    View on PubMed
  6. Yue JK, Cnossen MC, Winkler EA, Deng H, Phelps RRL, Coss NA, Sharma S, Robinson CK, Suen CG, Vassar MJ, Schnyer DM, Puccio AM, Gardner RC, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Lingsma HF, Manley GT. Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study. Front Neurol. 2019; 10:343.
    View on PubMed
  7. Payabvash S, Palacios EM, Owen JP, Wang MB, Tavassoli T, Gerdes M, Brandes-Aitken A, Mukherjee P, Marco EJ. White Matter Connectome Correlates of Auditory Over-Responsivity: Edge Density Imaging and Machine-Learning Classifiers. Front Integr Neurosci. 2019; 13:10.
    View on PubMed
  8. Payabvash S, Palacios EM, Owen JP, Wang MB, Tavassoli T, Gerdes M, Brandes-Aitken A, Cuneo D, Marco EJ, Mukherjee P. White Matter Connectome Edge Density in Children with Autism Spectrum Disorders: Potential Imaging Biomarkers Using Machine-Learning Models. Brain Connect. 2019 Mar; 9(2):209-220.
    View on PubMed
  9. Tavassoli T, Brandes-Aitken A, Chu R, Porter L, Schoen S, Miller LJ, Gerdes MR, Owen J, Mukherjee P, Marco EJ. Sensory over-responsivity: parent report, direct assessment measures, and neural architecture. Mol Autism. 2019; 10:4.
    View on PubMed
  10. Stein MB, Jain S, Giacino JT, Levin H, Dikmen S, Nelson LD, Vassar MJ, Okonkwo DO, Diaz-Arrastia R, Robertson CS, Mukherjee P, McCrea M, Mac Donald CL, Yue JK, Yuh E, Sun X, Campbell-Sills L, Temkin N, Manley GT, Adeoye O, Badjatia N, Boase K, Bodien Y, Bullock MR, Chesnut R, Corrigan JD, Crawford K, Diaz-Arrastia R, Dikmen S, Duhaime AC, Ellenbogen R, Feeser VR, Ferguson A, Foreman B, Gardner R, Gaudette E, Giacino JT, Gonzalez L, Gopinath S, Gullapalli R, Hemphill JC, Hotz G, Jain S, Korley F, Kramer J, Kreitzer N, Levin H, Lindsell C, Machamer J, Madden C, Martin A, McAllister T, McCrea M, Merchant R, Mukherjee P, Nelson LD, Noel F, Okonkwo DO, Palacios E, Perl D, Puccio A, Rabinowitz M, Robertson CS, Rosand J, Sander A, Satris G, Schnyer D, Seabury S, Sherer M, Stein MB, Taylor S, Toga A, Temkin N, Valadka A, Vassar MJ, Vespa P, Wang K, Yue JK, Yuh E, Zafonte R. Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury: A TRACK-TBI Study. JAMA Psychiatry. 2019 Jan 30.
    View on PubMed
  11. Keenan KE, Biller JR, Delfino JG, Boss MA, Does MD, Evelhoch JL, Griswold MA, Gunter JL, Hinks RS, Hoffman SW, Kim G, Lattanzi R, Li X, Marinelli L, Metzger GJ, Mukherjee P, Nordstrom RJ, Peskin AP, Perez E, Russek SE, Sahiner B, Serkova N, Shukla-Dave A, Steckner M, Stupic KF, Wilmes LJ, Wu HH, Zhang H, Jackson EF, Sullivan DC. Recommendations towards standards for quantitative MRI (qMRI) and outstanding needs. J Magn Reson Imaging. 2019 Jan 24.
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  12. Brandes-Aitken A, Anguera JA, Chang YS, Demopoulos C, Owen JP, Gazzaley A, Mukherjee P, Marco EJ. White Matter Microstructure Associations of Cognitive and Visuomotor Control in Children: A Sensory Processing Perspective. Front Integr Neurosci. 2018; 12:65.
    View on PubMed
  13. Shang Y, Hinkley LB, Cai C, Subramaniam K, Chang YS, Owen JP, Garrett C, Mizuiri D, Mukherjee P, Nagarajan SS, Cheung SW. Functional and Structural Brain Plasticity in Adult Onset Single-Sided Deafness. Front Hum Neurosci. 2018; 12:474.
    View on PubMed
  14. Shetty T, Nguyen JT, Cogsil T, Tsiouris AJ, Niogi SN, Kim EU, Dalal A, Halvorsen K, Cummings K, Zhang T, Masdeu JC, Mukherjee P, Marinelli L. Clinical Findings in a Multicenter MRI Study of Mild TBI. Front Neurol. 2018; 9:836.
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  15. Madhavan R, Joel SE, Mullick R, Cogsil T, Niogi SN, Tsiouris AJ, Mukherjee P, Masdeu JC, Marinelli L, Shetty T. Longitudinal Resting State Functional Connectivity Predicts Clinical Outcome in Mild Traumatic Brain Injury. J Neurotrauma. 2019 Mar 01; 36(5):650-660.
    View on PubMed
  16. Yue JK, Winkler EA, Puffer RC, Deng H, Phelps RRL, Wagle S, Morrissey MR, Rivera EJ, Runyon SJ, Vassar MJ, Taylor SR, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Schnyer DM, Puccio AM, Valadka AB, Okonkwo DO, Manley GT. Temporal lobe contusions on computed tomography are associated with impaired 6-month functional recovery after mild traumatic brain injury: a TRACK-TBI study. Neurol Res. 2018 Nov; 40(11):972-981.
    View on PubMed
  17. Korley FK, Yue JK, Wilson DH, Hrusovsky K, Diaz-Arrastia R, Ferguson AR, Yuh EL, Mukherjee P, Wang KKW, Valadka AB, Puccio AM, Okonkwo DO, Manley GT. Performance Evaluation of a Multiplex Assay for Simultaneous Detection of Four Clinically Relevant Traumatic Brain Injury Biomarkers. J Neurotrauma. 2018 Jul 23.
    View on PubMed
  18. Ngwenya LB, Gardner RC, Yue JK, Burke JF, Ferguson AR, Huang MC, Winkler EA, Pirracchio R, Satris GG, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT. Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study. Brain Inj. 2018; 32(9):1071-1078.
    View on PubMed
  19. Seabury SA, Gaudette É, Goldman DP, Markowitz AJ, Brooks J, McCrea MA, Okonkwo DO, Manley GT, Adeoye O, Badjatia N, Boase K, Bodien Y, Bullock MR, Chesnut R, Corrigan JD, Crawford K, Diaz-Arrastia R, Dikmen S, Duhaime AC, Ellenbogen R, Feeser VR, Ferguson A, Foreman B, Gardner R, Giacino J, Gonzalez L, Gopinath S, Gullapalli R, Hemphill JC, Hotz G, Jain S, Korley F, Kramer J, Kreitzer N, Levin H, Lindsell C, Machamer J, Madden C, Martin A, McAllister T, Merchant R, Mukherjee P, Nelson L, Noel F, Palacios E, Perl D, Puccio A, Rabinowitz M, Robertson C, Rosand J, Sander A, Satris G, Schnyer D, Sherer M, Stein M, Taylor S, Temkin N, Toga A, Valadka A, Vassar M, Vespa P, Wang K, Yue J, Yuh E, Zafonte R. Assessment of Follow-up Care After Emergency Department Presentation for Mild Traumatic Brain Injury and Concussion: Results From the TRACK-TBI Study. JAMA Netw Open. 2018 May 18; 1(1):e180210.
    View on PubMed
  20. Ouyang M, Dubois J, Yu Q, Mukherjee P, Huang H. Delineation of early brain development from fetuses to infants with diffusion MRI and beyond. Neuroimage. 2019 01 15; 185:836-850.
    View on PubMed

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