University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Michael Rosenblum, MD, PhD

Michael Rosenblum, MD, PhD

Assistant Professor, Dept. of Dermatology, UCSF

Cancer Center Program Memberships

Cancer Immunology

Education

University of Western Ontario, Canada, HBSc, 05/1997, Cell Biology
Medical College of Wisconsin, Milwaukee, PhD, 06/2003, Immunology
Medical College of Wisconsin, Milwaukee, MD, 06/2006, Medicine
University of California, San Francisco, Residency, 07/2010, Dermatology


Professional Experience

  • 1998-­2006
    Medical Scientist Training Program (MSTP), Medical College of Wisconsin
  • 2006-­2007
    Medical Internship, Aurora St. Luke's Transitional Year Program, Milwaukee, WI
  • 2007-­2010
    Dermatology Resident, UCSF Department of Dermatology, San Francisco, CA
  • 2009-­2012
    Postdoctoral Research Fellowship, Laboratory of Abul K. Abbas, UCSF
  • 2012-­present
    Assistant Professor of Dermatology, UCSF Department of Dermatology, San Francisco, CA

Honors & Awards

  • 2004
    Outstanding Doctoral Dissertation Award, Medical College of Wisconsin
  • 2006
    Armand J. Quick Award for Outstanding Senior Medical Student in Biochemistry, Medical College of Wisconsin
  • 2014
    NIH Director's New Innovator Award
  • 2015
    Charles & Daneen Stiefel Scholar Award in Autoimmune & Connective Tissue Diseases

Selected Publications

  1. Lowe MM, Rosenblum MD. They Mite B GCs. Sci Immunol. 2019 Oct 04; 4(40).
    View on PubMed
  2. Kalekar LA, Cohen JN, Prevel N, Sandoval PM, Mathur AN, Moreau JM, Lowe MM, Nosbaum A, Wolters PJ, Haemel A, Boin F, Rosenblum MD. Regulatory T cells in skin are uniquely poised to suppress profibrotic immune responses. Sci Immunol. 2019 Sep 06; 4(39).
    View on PubMed
  3. Kalekar LA, Rosenblum MD. Regulatory T cells in inflammatory skin disease: from mice to humans. Int Immunol. 2019 Jul 13; 31(7):457-463.
    View on PubMed
  4. Klicznik MM, Morawski PA, Höllbacher B, Varkhande SR, Motley SJ, Kuri-Cervantes L, Goodwin E, Rosenblum MD, Long SA, Brachtl G, Duhen T, Betts MR, Campbell DJ, Gratz IK. Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals. Sci Immunol. 2019 Jul 05; 4(37).
    View on PubMed
  5. Remedios KA, Meyer L, Zirak B, Pauli ML, Truong HA, Boda D, Rosenblum MD. CD27 Promotes CD4+ Effector T Cell Survival in Response to Tissue Self-Antigen. J Immunol. 2019 Aug 01; 203(3):639-646.
    View on PubMed
  6. Cohen JN, Rosenblum MD. Y'all comeback now. Sci Immunol. 2019 May 03; 4(35).
    View on PubMed
  7. Miao Y, Yang H, Levorse J, Yuan S, Polak L, Sribour M, Singh B, Rosenblum MD, Fuchs E. Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells. Cell. 2019 May 16; 177(5):1172-1186.e14.
    View on PubMed
  8. Mathur AN, Zirak B, Boothby IC, Tan M, Cohen JN, Mauro TM, Mehta P, Lowe MM, Abbas AK, Ali N, Rosenblum MD. Treg-Cell Control of a CXCL5-IL-17 Inflammatory Axis Promotes Hair-Follicle-Stem-Cell Differentiation During Skin-Barrier Repair. Immunity. 2019 03 19; 50(3):655-667.e4.
    View on PubMed
  9. Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, Arce Vargus F, Sheppard D, Hann BC, Mirza A, Quezada SA, Rosenblum MD, Krummel MF, Balmain A, Akhurst RJ. a-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by a-TGFß antibody to promote durable rejection and immunity in squamous cell carcinomas. J Immunother Cancer. 2019 Mar 04; 7(1):62.
    View on PubMed
  10. Dall'Era M, Pauli ML, Remedios K, Taravati K, Sandova PM, Putnam AL, Lares A, Haemel A, Tang Q, Hellerstein M, Fitch M, McNamara J, Welch B, Bluestone JA, Wofsy D, Rosenblum MD. Adoptive Treg Cell Therapy in a Patient With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2019 Mar; 71(3):431-440.
    View on PubMed
  11. Moreau JM, Rosenblum MD. Inflammatory T cells maintain a healing disposition. Sci Immunol. 2019 Jan 04; 4(31).
    View on PubMed
  12. Remedios KA, Zirak B, Sandoval PM, Lowe MM, Boda D, Henley E, Bhattrai S, Scharschmidt TC, Liao W, Naik HB, Rosenblum MD. The TNFRSF members CD27 and OX40 coordinately limit TH17 differentiation in regulatory T cells. Sci Immunol. 2018 12 21; 3(30).
    View on PubMed
  13. Emrick JJ, Mathur A, Wei J, Gracheva EO, Gronert K, Rosenblum MD, Julius D. Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E12091-E12100.
    View on PubMed
  14. Mehta P, Rosenblum MD. Colitis interruptus: LAGing gut inflammation. Sci Immunol. 2018 09 07; 3(27).
    View on PubMed
  15. Chang HW, Yan D, Singh R, Liu J, Lu X, Ucmak D, Lee K, Afifi L, Fadrosh D, Leech J, Vasquez KS, Lowe MM, Rosenblum MD, Scharschmidt TC, Lynch SV, Liao W. Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization. Microbiome. 2018 09 05; 6(1):154.
    View on PubMed
  16. Ahn R, Yan D, Chang HW, Lee K, Bhattarai S, Huang ZM, Nakamura M, Singh R, Afifi L, Taravati K, Munoz-Sandoval P, Pauli M, Rosenblum MD, Liao W. RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways. Sci Rep. 2018 07 27; 8(1):11368.
    View on PubMed
  17. Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nat Med. 2018 08; 24(8):1178-1191.
    View on PubMed
  18. Wang D, Quiros J, Mahuron K, Pai CC, Ranzani V, Young A, Silveria S, Harwin T, Abnousian A, Pagani M, Rosenblum MD, Van Gool F, Fong L, Bluestone JA, DuPage M. Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity. Cell Rep. 2018 06 12; 23(11):3262-3274.
    View on PubMed
  19. Mande P, Zirak B, Ko WC, Taravati K, Bride KL, Brodeur TY, Deng A, Dresser K, Jiang Z, Ettinger R, Fitzgerald KA, Rosenblum MD, Harris JE, Marshak-Rothstein A. Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation. J Clin Invest. 2018 07 02; 128(7):2966-2978.
    View on PubMed
  20. Kalekar LA, Rosenblum MD. Say it isn't pso: IL-25 drives skin inflammation. Sci Immunol. 2018 05 04; 3(23).
    View on PubMed

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