University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Maria Wei, MD, PhD

Maria Wei, MD, PhD

Professor of Dermatology; Director, Melanoma Surveillance Clinic; Director, Dermatology Genetics/Familial Cancer Syndrome Clinic, UCSF

Cancer Center Program Memberships

Cancer Genetics

Education

University of Michigan, Ann Arbor, MI B.S., High Honors, 1983, Chemistry, Computer Science
Duke University, Durham, NC Ph.D. 1991 Immunology
Duke University, Durham, NC M.D. 1992 Medicine
Brigham and Women’s Hospital, Boston, MA Intern 1993 Internal Medicine
University of California, San Francisco Resident 1996 Dermatology
University of California, San Francisco Fellow 1997 Biochemistry/Biophysics


Professional Experience

  • 1997-2003
    Clinical Instructor, Department of Dermatology, University of California, San Francisco
  • 1997-present
    Staff Physician, Dermatology Service, San Francisco Veterans Affairs Medical Center
  • 2003-2010
    Assistant Professor, of Dermatology, University of California, San Francisco
  • 2009-present
    Director, Pigmented Lesion Clinic/Melanoma Surveillance Clinic, UCSF
  • 2010-2018
    Associate Professor, Department of Dermatology, University of California, San Francisco
  • 2015-present
    Director, Dermatology Genetics Clinic, UCSF
  • 2018-present
    Professor, Department of Dermatology, University of California, San Francisco

Honors & Awards

  • 1998
    Mentorship Award, Women's Dermatologic Society
  • 1999
    Research Career Development Award, Department of Veterans Affairs
  • 2005
    Young Investigator Award, NCIRE/SFVAMC
  • 2013
    Estella Medrano Award, PanAmerican Society for Pigment Cell Research
  • 2014
    Bay Area's Top Docs, Melanoma and Pigment Disorders, San Francisco Magazine
  • 2015
    Bay Area's Top Docs, Melanoma and Pigment Disorders, San Francisco Magazine
  • 2016
    Bay Area's Top Docs, Melanoma and Pigment Disorders, San Francisco Magazine
  • 2017
    Bay Area's Top Docs, Melanoma and Pigment Disorders, San Francisco Magazine
  • 2017
    Cancer Center Impact Grant
  • 2018
    Bay Area's Top Docs, Melanoma and Pigment Disorders, San Francisco Magazine

Selected Publications

  1. Xiong M, Pfau J, Young AT, Wei ML. Artificial Intelligence in Teledermatology. Curr Derm Rep. 2019.
    View on PubMed
  2. Yu WY, Wei ML. Suction Blisters. JAMA Dermatol. 2018 Dec 12.
    View on PubMed
  3. Jeter JM, Bowles TL, Curiel-Lewandrowski C, Swetter SM, Filipp FV, Abdel-Malek ZA, Geskin LJ, Brewer JD, Arbiser JL, Gershenwald JE, Chu EY, Kirkwood JM, Box NF, Funchain P, Fisher DE, Kendra KL, Marghoob AA, Chen SC, Ming ME, Albertini MR, Vetto JT, Margolin KA, Pagoto SL, Hay JL, Grossman D, Ellis DL, Kashani-Sabet M, Mangold AR, Markovic SN, Nelson KC, Powers JG, Robinson JK, Sahni D, Sekulic A, Sondak VK, Wei ML, Zager JS, Dellavalle RP, Thompson JA, Weinstock MA, Leachman SA, Cassidy PB. Chemoprevention agents for melanoma: A path forward into phase 3 clinical trials. Cancer. 2019 Jan 01; 125(1):18-44.
    View on PubMed
  4. Nosrati A, Yu WY, McGuire J, Griffin A, de Souza JR, Singh R, Linos E, Chren MM, Grimes B, Jewell NP, Wei ML. Outcomes and Risk Factors in Patients with Multiple Primary Melanomas. J Invest Dermatol. 2019 Jan; 139(1):195-201.
    View on PubMed
  5. Bhattacharya A, Young A, Wong A, Stalling S, Wei M, Hadley D . Precision diagnosis of melanoma and other skin lesions from digital images. AMIA Jt Summits Transl Sci Proc. 2017; 220-226.
    View on PubMed
  6. Nosrati A, Berliner JG, Goel S, McGuire J, Morhenn V, de Souza JR, Yeniay Y, Singh R, Lee K, Nakamura M, Wu RR, Griffin A, Grimes B, Linos E, Chren MM, Grekin R, Wei ML. Outcomes of Melanoma In Situ Treated With Mohs Micrographic Surgery Compared With Wide Local Excision. JAMA Dermatol. 2017 05 01; 153(5):436-441.
    View on PubMed
  7. Singh RK, Lee KM, Vujkovic-Cvijin I, Ucmak D, Farahnik B, Abrouk M, Nakamura M, Zhu TH, Bhutani T, Wei M, Liao W. The role of IL-17 in vitiligo: A review. Autoimmun Rev. 2016 Apr; 15(4):397-404.
    View on PubMed
  8. Choudhry A, Hong J, Chong K, Jiang B, Hartman R, Chu E, Nelson K, Wei ML, Nguyen T. Patients' preferences for biopsy result notification in an era of electronic messaging methods. JAMA Dermatol. 2015 May; 151(5):513-21.
    View on PubMed
  9. Yue L, Huang ZM, Fong S, Leong S, Jakowatz JG, Charruyer-Reinwald A, Wei M, Ghadially R. Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma. Melanoma Res. 2015 Apr; 25(2):138-48.
    View on PubMed
  10. Nosrati A, Wei ML. Sex disparities in melanoma outcomes: the role of biology. Arch Biochem Biophys. 2014 Dec 01; 563:42-50.
    View on PubMed
  11. Man MQ, Lin TK, Santiago JL, Celli A, Zhong L, Huang ZM, Roelandt T, Hupe M, Sundberg JP, Silva KA, Crumrine D, Martin-Ezquerra G, Trullas C, Sun R, Wakefield JS, Wei ML, Feingold KR, Mauro TM, Elias PM. Basis for enhanced barrier function of pigmented skin. J Invest Dermatol. 2014 Sep; 134(9):2399-2407.
    View on PubMed
  12. Huang ZM, Chinen M, Chang PJ, Xie T, Zhong L, Demetriou S, Patel MP, Scherzer R, Sviderskaya EV, Bennett DC, Millhauser GL, Oh DH, Cleaver JE, Wei ML. Targeting protein-trafficking pathways alters melanoma treatment sensitivity. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):553-8.
    View on PubMed
  13. Agarwal P, Verzi MP, Nguyen T, Hu J, Ehlers ML, McCulley DJ, Xu SM, Dodou E, Anderson JP, Wei ML, Black BL. The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10. Development. 2011 Jun; 138(12):2555-65.
    View on PubMed
  14. Xie T, Nguyen T, Hupe M, Wei ML. Multidrug resistance decreases with mutations of melanosomal regulatory genes. Cancer Res. 2009 Feb 01; 69(3):992-9.
    View on PubMed
  15. Nguyen T, Wei ML. Hermansky-Pudlak HPS1/pale ear gene regulates epidermal and dermal melanocyte development. J Invest Dermatol. 2007 Feb; 127(2):421-8.
    View on PubMed
  16. Wei ML. Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function. Pigment Cell Res. 2006 Feb; 19(1):19-42.
    View on PubMed
  17. Nguyen T, Wei ML. Characterization of melanosomes in murine Hermansky-Pudlak syndrome: mechanisms of hypopigmentation. J Invest Dermatol. 2004 Feb; 122(2):452-60.
    View on PubMed
  18. Nguyen T, Novak EK, Kermani M, Fluhr J, Peters LL, Swank RT, Wei ML. Melanosome morphologies in murine models of hermansky-pudlak syndrome reflect blocks in organelle development. J Invest Dermatol. 2002 Nov; 119(5):1156-64.
    View on PubMed
  19. Storkus WJ, Wei M, Cresswell P, Dawson JR. Class I-like CD1A-C do not protect target cells from NK-mediated cytolysis. Cell Immunol. 1996 Jan 10; 167(1):154-6.
    View on PubMed
  20. Anderson KS, Alexander J, Wei M, Cresswell P. Intracellular transport of class I MHC molecules in antigen processing mutant cell lines. J Immunol. 1993 Oct 01; 151(7):3407-19.
    View on PubMed

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