Education

07/2022 - Internal Medicine, University of California, San Francisco
MD, 05/2020 - Medicine, Weill Cornell Medical College
PhD, 08/2019 - Genetics, Molecular Biology, DNA Repair, The Rockefeller University
- Hematology and Oncology, University of California, San Francisco

Honors & Awards

  • 2026-2027
    ASCO Conquer Cancer Foundation Young Investigator Award, PI
  • 2025-2028
    Prostate Cancer Foundation Young Investigator Award, PI
  • 2025-2027
    UCSF Prostate Spore DRP – NIH/NCI (P50CA275741): Targeting therapeutic vulnerabilities of DNA repair deficient prostate cancer, Co-PI
  • 2025-2028
    Prostate Cancer Foundation Young Investigator Award, PI
  • 2025-2026
    2025 BRCA Research & Cure Alliance (CureBRCA) Grant, PI                   
  • 2025-2026
    Rosenberg Fellowship in Genitourinary Medical Oncology
  • 2025
    UCSF NIH T32 Training Grant: Molecular and Cellular Mechanisms in Cancer (T32CA108462)
  • 2024-2025
    UCSF Prostate Cancer Program 2023 Pilot Research Award: Defining prostate cancer tumor-immune system interactions in BRCA2
  • 2018-2019
    Pilot Grant #UL1TR000043: Novel bone marrow failure and DNA repair deficiency syndrome, Rockefeller University NIH CTSA program
  • 2017-2018
    Pilot Grant #UL1 TR001866: Novel bone marrow failure and DNA repair deficiency syndrome, Rockefeller University NIH CTSA program

Selected Publications

  1. Schultz-Rogers L, Lach FP, Rickman KA, Ferrer A, Mangaonkar AA, Schwab TL, Schmitz CT, Clark KJ, Dsouza NR, Zimmermann MT, Litzow M, Jacobi N, Klee EW, Smogorzewska A, Patnaik MM. A homozygous missense variant in UBE2T is associated with a mild Fanconi anemia phenotype. Haematologica. 2021 04 01; 106(4):1188-1192. View on PubMed
  2. Lach FP, Singh S, Rickman KA, Ruiz PD, Noonan RJ, Hymes KB, DeLacure MD, Kennedy JA, Chandrasekharappa SC, Smogorzewska A. Esophageal cancer as initial presentation of Fanconi anemia in patients with a hypomorphic FANCA variant. Cold Spring Harb Mol Case Stud. 2020 12; 6(6). View on PubMed
  3. Rickman KA, Noonan RJ, Lach FP, Sridhar S, Wang AT, Abhyankar A, Huang A, Kelly M, Auerbach AD, Smogorzewska A. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links. Genes Dev. 2020 06 01; 34(11-12):832-846. View on PubMed
  4. Rickman K, Smogorzewska A. Advances in understanding DNA processing and protection at stalled replication forks. J Cell Biol. 2019 04 01; 218(4):1096-1107. View on PubMed
  5. Lv Z, Rickman KA, Yuan L, Williams K, Selvam SP, Woosley AN, Howe PH, Ogretmen B, Smogorzewska A, Olsen SK. S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. Mol Cell. 2017 Feb 16; 65(4):699-714.e6. View on PubMed
  6. Rickman KA, Lach FP, Abhyankar A, Donovan FX, Sanborn EM, Kennedy JA, Sougnez C, Gabriel SB, Elemento O, Chandrasekharappa SC, Schindler D, Auerbach AD, Smogorzewska A. Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia. Cell Rep. 2015 Jul 07; 12(1):35-41. View on PubMed
  7. Ouyang J, Garner E, Hallet A, Nguyen HD, Rickman KA, Gill G, Smogorzewska A, Zou L. Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance. Mol Cell. 2015 Jan 08; 57(1):108-22. View on PubMed
  8. Rickman KA, Swancutt KL, Mezyk SP, Kiddle JJ. Isoniazid: Radical-induced oxidation and reduction chemistry. Bioorg Med Chem Lett. 2013 May 15; 23(10):3096-100. View on PubMed
  9. Toth JE, Rickman KA, Venter AR, Kiddle JJ, Mezyk SP. Reaction kinetics and efficiencies for the hydroxyl and sulfate radical based oxidation of artificial sweeteners in water. J Phys Chem A. 2012 Oct 11; 116(40):9819-24. View on PubMed
  10. Rickman KA, Mezyk SP. Kinetics and mechanisms of sulfate radical oxidation of β-lactam antibiotics in water. Chemosphere. 2010 Sep; 81(3):359-65. View on PubMed

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