Education

M.D., 2003 - School of Medicine, Harvard University
Residency, - School of Medicine - Pediatrics, University of California, San Francisco

Selected Publications

  1. Shimano KA, Vanderpoel V, Stone H, Resar L, Kucine N. Clinical features associated with thrombotic events in children with myeloproliferative neoplasms. Am J Hematol. 2022 Sep; 97(9):E353-E355.  View on PubMed
  2. Lloyd-McLennan AM, Shimano KA, Dorsey M, Cordoro KM. Eczema and Petechiae in an Infant. Pediatr Rev. 2022 07 01; 43(7):e19-e23.  View on PubMed
  3. Higham CS, Shimano KA, Melton A, Kharbanda S, Chu J, Dara J, Winestone LE, Hermiston ML, Huang JN, Dvorak CC. A pilot trial of prophylactic defibrotide to prevent serious thrombotic microangiopathy in high-risk pediatric patients. Pediatr Blood Cancer. 2022 05; 69(5):e29641.  View on PubMed
  4. Shimano KA, Eng W, Adams DM. How we approach the use of sirolimus and new agents: Medical therapy to treat vascular anomalies. Pediatr Blood Cancer. 2022 08; 69 Suppl 3:e29603.  View on PubMed
  5. Forlanini F, Zinter MS, Dvorak CC, Bailey-Olson M, Winestone LE, Shimano KA, Higham CS, Melton A, Chu J, Kharbanda S. Hematopoietic Cell Transplantation-Comorbidity Index Score Is Correlated with Treatment-Related Mortality and Overall Survival following Second Allogeneic Hematopoietic Cell Transplantation in Children. Transplant Cell Ther. 2022 03; 28(3):155.e1-155.e8.  View on PubMed
  6. Aarati V Rao, Katharine L Ostedgaard, Youran Zou, Kristin A. Shimano. An Unusual Presentation of Kaposiform Hemangioendothelioma in the Mandibular Bone. Blood. 2021 Nov 5; 138(Supplement 1):4205-4205.  View on PubMed
  7. Daniel L. Cooke, Ilona J. Frieden, Kristin A. Shimano. Angiographic Evidence of Response to Trametinib Therapy for a Spinal Cord Arteriovenous Malformation. . 2021 Sep 1; 2(3):e018.  View on PubMed
  8. Shimano KA, Grace RF, Despotovic JM, Neufeld EJ, Klaassen RJ, Bennett CM, Ma C, London WB, Neunert C. Phase 3 randomised trial of eltrombopag versus standard first-line pharmacological management for newly diagnosed immune thrombocytopaenia (ITP) in children: study protocol. BMJ Open. 2021 08 27; 11(8):e044885.  View on PubMed
  9. Shimano KA, Narla A, Rose MJ, Gloude NJ, Allen SW, Bergstrom K, Broglie L, Carella BA, Castillo P, de Jong JLO, Dror Y, Geddis AE, Huang JN, Lau BW, McGuinn C, Nakano TA, Overholt K, Rothman JA, Sharathkumar A, Shereck E, Vlachos A, Olson TS, Bertuch AA, Wlodarski MW, Shimamura A, Boklan J. Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium. Am J Hematol. 2021 11 01; 96(11):1491-1504.  View on PubMed
  10. Weiss NM, Kuzniewicz MW, Shimano KA, Walsh EM, Newman TB. Use of Complete Blood Cell Count Components to Screen for Hereditary Spherocytosis in Neonates. Pediatrics. 2021 09; 148(3).  View on PubMed
  11. Higham CS, Collins G, Shimano KA, Melton A, Kharbanda S, Winestone LE, Huang JN, Dara J, Long-Boyle JR, Dvorak CC. Transplant-associated thrombotic microangiopathy in pediatric patients: pre-HSCT risk stratification and prophylaxis. Blood Adv. 2021 04 27; 5(8):2106-2114.  View on PubMed
  12. Shimano KA, Neunert C, Bussel JB, Klaassen RJ, Bhat R, Pastore YD, Lambert MP, Bennett CM, Despotovic JM, Forbes P, Grace RF. Quality of life is an important indication for second-line treatment in children with immune thrombocytopenia. Pediatr Blood Cancer. 2021 06; 68(6):e29023.  View on PubMed
  13. Christine S Higham, Alexis Melton, Sandhya Kharbanda, Jasmeen Dara, Lena E. Winestone, James N Huang, Kristin A. Shimano. A Pilot Trial of Pre-Transplant Risk Stratification and Prophylactic Defibrotide to Prevent Serious Thrombotic Microangiopathy in High-Risk Pediatric Hematopoietic Stem Cell Transplant Patients. Blood. 2020 Nov 5; 136(Supplement 1):9-10.  View on PubMed
  14. David T. Teachey, Meenakshi Devidas, Brent L Wood, Zhiguo Chen, Robert James Hayashi, Robert D Annett, Barbara L Asselin, Keith J August, Steve Y Cho, Kimberly P. Dunsmore, Brian T. Fisher, Jason L. Freedman, Paul J. Galardy, Paul Harker-Murray, Michelle L. Hermiston, Terzah M Horton, Alok I Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir I Patel, Eric S. Schafer, Tal Schechter-Finkelstein, Kristin A. Shimano, Neelam Singh, Amii C. Steele, Maria L. Sulis, Sarah L Vargas, Stuart S. Winter, Charlotte Wood, Patrick Zweider McKay, Catherine M. Bollard, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz. Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231. Blood. 2020 Nov 5; 136(Supplement 1):11-12.  View on PubMed
  15. Edwards EA, Phelps AS, Cooke D, Frieden IJ, Zapala MA, Fullerton HJ, Shimano KA. Monitoring Arteriovenous Malformation Response to Genotype-Targeted Therapy. Pediatrics. 2020 09; 146(3).  View on PubMed
  16. Contreras CF, Long-Boyle JR, Shimano KA, Melton A, Kharbanda S, Dara J, Higham C, Huang JN, Cowan MJ, Dvorak CC. Reduced Toxicity Conditioning for Nonmalignant Hematopoietic Cell Transplants. Biol Blood Marrow Transplant. 2020 09; 26(9):1646-1654.  View on PubMed
  17. Grace RF, Klaassen RJ, Shimano KA, Lambert MP, Grimes A, Bussel JB, Breakey VR, Pastore YD, Black V, Overholt K, Bhat R, Forbes PW, Neunert C. Fatigue in children and adolescents with immune thrombocytopenia. Br J Haematol. 2020 10; 191(1):98-106.  View on PubMed
  18. Friend BD, Bailey-Olson M, Melton A, Shimano KA, Kharbanda S, Higham C, Winestone LE, Huang J, Stieglitz E, Dvorak CC. The impact of total body irradiation-based regimens on outcomes in children and young adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2020 02; 67(2):e28079.  View on PubMed
  19. Kristin A. Shimano, Rachael F. Grace, Carolyn M. Bennett, Robert J Klaassen, Cindy Neunert, Ellis J. Neufeld, Clement Ma, Wendy B. London, Jenny M. Despotovic. A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children. Blood. 2019 Nov 13; 134(Supplement_1):2369-2369.  View on PubMed
  20. Cristina F Contreras, Janel R Long-Boyle, Kristin A. Shimano, Jasmeen Dara, James N Huang, Sandhya Kharbanda, Alexis Melton, Christine Higham, Morton J Cowan, Christopher C. Dvorak. Reduced Toxicity Conditioning for Non-Malignant Hematopoietic Cell Transplants. Blood. 2019 Nov 13; 134(Supplement_1):4481-4481.  View on PubMed

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