Research Summary

Dr. Jonathan P. Terdiman is a Professor of Clinical Medicine and Surgery and the Chief of the Gastroenterology Division at UCSF Health. He earned his undergraduate degree from Princeton University in 1985 and his medical degree from the Columbia University College of Physicians and Surgeons in 1989. Dr. Terdiman then completed his residency in internal medicine and fellowships in critical care medicine and gastroenterology at UCSF before joining the faculty in 1996.

Dr. Terdiman has a busy clinical practice in gastroenterology, with a focus on the management of patients with inflammatory bowel disease and those at high risk for gastrointestinal cancer. In 2013 Dr Terdiman was elected to the UCSF Department of Medicine’s Master Clinician Council, and he has been named a Bay area Top Doctor by San Francisco Magazine for the past ten years and counting. In 2022 Dr. Terdiman was honored to receive the White Helmet Award from the San Francisco Firefighters Foundation in recognition of his work in cancer prevention among firefighters. Dr. Terdiman also is a leading teacher of clinical medicine at UCSF. He has received numerous campus-wide teaching awards, and he is a past member of the Haile T Debas Academy of Medical Educators. Dr. Terdiman’s primary research activities focus on the assessment and mitigation of cancer risk among patients at high risk because of a genetic predisposition to the disease. He also is actively engaged in projects assessing the safety and efficacy of new therapies for inflammatory bowel disease.

In addition to his work at UCSF, Dr. Terdiman served on the board of trustees of the northern California chapter of the Crohn’s and Colitis Foundation of America (CCFA) for many years, and he was board president from 2010-2012. In 2012 the chapter named Dr. Terdiman as a CCFA Champion of Hope. Dr. Terdiman currently is the chair of the board of trustees of the Brandeis School of San Francisco.

Education

Princeton University, A.B., cum laude, 1985
Columbia University, College of Physicians and Surgeons, M.D., 1989

Honors & Awards

  • 2000
    UCSF Medical School Class of 2002, Excellence in Small Group Instruction, recipient
  • 2002
    UCSF Medical School Class of 2004, Excellence in Small Group Instruction, recipient
  • 2004
    UCSF Medical School Class of 2006, Excellence in Small Group Instruction, recipient
  • 2005
    Excellence in Direct Teaching, recipient, UCSF Academy of Medical Educators

Selected Publications

  1. Mennillo E, Kim YJ, Rusu I, Lee G, Dorman LC, Bernard-Vazquez F, Bain JL, Patel R, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Naser M, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. Single-cell and spatial multi-omics identify innate and stromal modules targeted by anti-integrin therapy in ulcerative colitis. bioRxiv. 2023 Jan 22.  View on PubMed
  2. Chugh R, Braga-Neto MB, Fredrick TW, Ramos GP, Terdiman J, El-Nachef N, Loftus EV, Mahadevan U, Kane SV. Multicenter Real-world Experience of Upadacitinib in the Treatment of Crohn's Disease. J Crohns Colitis. 2022 Oct 22.  View on PubMed
  3. Wang CW, Mclean I R, Cheng YW, Kim S, Terdiman J, Kathpalia P, Beck KR. Racial Disparities in Endoscopy Cancellations During the COVID-19 Pandemic. Dig Dis Sci. 2022 Jun 22.  View on PubMed
  4. Smith BJ, Piceno Y, Zydek M, Zhang B, Syriani LA, Terdiman JP, Kassam Z, Ma A, Lynch SV, Pollard KS, El-Nachef N. Strain-resolved analysis in a randomized trial of antibiotic pretreatment and maintenance dose delivery mode with fecal microbiota transplant for ulcerative colitis. Sci Rep. 2022 04 01; 12(1):5517.  View on PubMed
  5. Feuerstein JD, Ho EY, Shmidt E, Singh H, Falck-Ytter Y, Sultan S, Terdiman JP, American Gastroenterological Association Institute Clinical Guidelines Committee. AGA Clinical Practice Guidelines on the Medical Management of�Moderate to Severe Luminal and Perianal Fistulizing Crohn's�Disease. Gastroenterology. 2021 06; 160(7):2496-2508.  View on PubMed
  6. Ho EY, Singh S, Terdiman JP. Providing the Best Care for Patients With Crohn's Disease: An Examination of the New AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease. Gastroenterology. 2021 06; 160(7):2557-2562.  View on PubMed
  7. Shmidt E, Ho EY, Feuerstein JD, Singh S, Terdiman JP. Spotlight: Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease. Gastroenterology. 2021 06; 160(7):2511.  View on PubMed
  8. Provenzale D, Ness RM, Llor X, Weiss JM, Abbadessa B, Cooper G, Early DS, Friedman M, Giardiello FM, Glaser K, Gurudu S, Halverson AL, Issaka R, Jain R, Kanth P, Kidambi T, Lazenby AJ, Maguire L, Markowitz AJ, May FP, Mayer RJ, Mehta S, Patel S, Peter S, Stanich PP, Terdiman J, Keller J, Dwyer MA, Ogba N. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 2.2020. J Natl Compr Canc Netw. 2020 10 01; 18(10):1312-1320.  View on PubMed
  9. Kotwani P, Terdiman J, Lewin S. Tofacitinib for Rescue Therapy in Acute Severe Ulcerative Colitis: A Real-world Experience. J Crohns Colitis. 2020 Jul 30; 14(7):1026-1028.  View on PubMed
  10. Lee JK, Kidambi TD, Kaltenbach T, Bhat YM, Shergill A, McQuaid KR, Terdiman JP, Soetikno RM. Impact of observational training on endoscopic mucosal resection outcomes and competency for large colorectal polyps: single endoscopist experience. Endosc Int Open. 2020 Mar; 8(3):E346-E353.  View on PubMed
  11. Singh S, Allegretti JR, Siddique SM, Terdiman JP. AGA Technical Review on the Management of Moderate to Severe Ulcerative Colitis. Gastroenterology. 2020 04; 158(5):1465-1496.e17.  View on PubMed
  12. Selvig D, Piceno Y, Terdiman J, Zydek M, Umetsu SE, Balitzer D, Fadrosh D, Lynch K, Lamere B, Leith T, Kassam Z, Beck K, Lewin S, Ma A, Somsouk M, Lynch SV, El-Nachef N. Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study. Dig Dis Sci. 2020 04; 65(4):1099-1106.  View on PubMed
  13. Gutin L, Piceno Y, Fadrosh D, Lynch K, Zydek M, Kassam Z, LaMere B, Terdiman J, Ma A, Somsouk M, Lynch S, El-Nachef N. Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile. United European Gastroenterol J. 2019 07; 7(6):807-814.  View on PubMed
  14. Adler E, Tabaa A, Kassam Z, Zydek M, Terdiman J, El-Nachef N. Capsule-Delivered Fecal Microbiota Transplant Is Safe and Well Tolerated in Patients with Ulcerative Colitis. Dig Dis Sci. 2019 09; 64(9):2452-2454.  View on PubMed
  15. Mao EJ, Lewin S, Terdiman JP, Beck K. Safety of dual biological therapy in Crohn's disease: a case series of vedolizumab in combination with other biologics. BMJ Open Gastroenterol. 2018; 5(1):e000243.  View on PubMed
  16. Kidambi TD, Terdiman JP, Lee JK. Negative withdrawal time: simple and efficient. Gastrointest Endosc. 2018 10; 88(4):781.  View on PubMed
  17. Kidambi TD, Terdiman JP, El-Nachef N, Singh A, Kattah MG, Lee JK. Effect of I-scan Electronic Chromoendoscopy on Detection of Adenomas During Colonoscopy. Clin Gastroenterol Hepatol. 2019 03; 17(4):701-708.e1.  View on PubMed
  18. Kidambi TD, Goldberg D, Nussbaum R, Blanco A, Umetsu SE, Terdiman JP, Lee JK. Novel variant of unknown significance in MUTYH in a patient with MUTYH-associated polyposis: a case to reclassify. Clin J Gastroenterol. 2018 Dec; 11(6):457-460.  View on PubMed
  19. Gray PN, Tsai P, Chen D, Wu S, Hoo J, Mu W, Li B, Vuong H, Lu HM, Batth N, Willett S, Uyeda L, Shah S, Gau CL, Umali M, Espenschied C, Janicek M, Brown S, Margileth D, Dobrea L, Wagman L, Rana H, Hall MJ, Ross T, Terdiman J, Cullinane C, Ries S, Totten E, Elliott AM. TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome. Oncotarget. 2018 Apr 17; 9(29):20304-20322.  View on PubMed
  20. Kidambi TD, Pedley C, Blanco A, Bergsland EK, Terdiman JP. Lower gastrointestinal neuroendocrine neoplasms associated with hereditary cancer syndromes: a case series. Fam Cancer. 2017 10; 16(4):537-543.  View on PubMed

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